p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol.

Valosin Containing Protein / metabolism Humans Cytosol / metabolism Cell Nucleus / metabolism Mutation Active Transport, Cell Nucleus DNA Damage Adenosine Triphosphatases / metabolism Cell Cycle Proteins / metabolism Protein Transport Nuclear Proteins / metabolism DNA Repair Autophagy Protein Binding HEK293 Cells Adaptor Proteins, Signal Transducing

Journal

Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440

Informations de publication

Date de publication:
03 May 2024
Historique:
medline: 3 5 2024
pubmed: 3 5 2024
entrez: 3 5 2024
Statut: ppublish

Résumé

The AAA

Identifiants

DOI: 10.1126/sciadv.adl6082 PMID: 38701207
pubmed: 38701207
doi: 10.1126/sciadv.adl6082
doi:

Substances chimiques

Valosin Containing Protein EC 3.6.4.6
VCP protein, human EC 3.6.4.6
p37 protein, human 0
Adenosine Triphosphatases EC 3.6.1.-
Cell Cycle Proteins 0
Nuclear Proteins 0
Adaptor Proteins, Signal Transducing 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

eadl6082

Auteurs

Lidia Wrobel (L)

Department of Medical Genetics, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK.
UK Dementia Research Institute, University of Cambridge, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK.
ORCID: 0000-0002-5127-5616

Johanna L Hoffmann (JL)

Department of Medical Genetics, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK.
UK Dementia Research Institute, University of Cambridge, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK.
ORCID: 0009-0006-2552-3176

Xinyi Li (X)

Department of Medical Genetics, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK.
UK Dementia Research Institute, University of Cambridge, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK.

David C Rubinsztein (DC)

Department of Medical Genetics, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK.
UK Dementia Research Institute, University of Cambridge, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK.
ORCID: 0000-0001-5002-5263

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines du cycle cellulaire › Protéine contenant la valosine › p37 regulates VCP/p97 shuttling and functions...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › p37 regulates VCP/p97 shuttling and functions...
questionsmedicales.fr › Cellules › Structures cellulaires › Fractions subcellulaires › Cytosol › p37 regulates VCP/p97 shuttling and functions...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Noyau de la cellule › p37 regulates VCP/p97 shuttling and functions...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Mutation › p37 regulates VCP/p97 shuttling and functions...
questionsmedicales.fr › Métabolisme › Transport biologique › Transport des protéines › Transport nucléaire actif › p37 regulates VCP/p97 shuttling and functions...
questionsmedicales.fr › Phénomènes génétiques › Altération de l'ADN › p37 regulates VCP/p97 shuttling and functions...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Acid anhydride hydrolases › Adenosine triphosphatases › p37 regulates VCP/p97 shuttling and functions...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines du cycle cellulaire › p37 regulates VCP/p97 shuttling and functions...
questionsmedicales.fr › Métabolisme › Transport biologique › Transport des protéines › p37 regulates VCP/p97 shuttling and functions...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines nucléaires › p37 regulates VCP/p97 shuttling and functions...
questionsmedicales.fr › Phénomènes génétiques › Réparation de l'ADN › p37 regulates VCP/p97 shuttling and functions...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Autophagie › p37 regulates VCP/p97 shuttling and functions...
questionsmedicales.fr › Métabolisme › Liaison aux protéines › p37 regulates VCP/p97 shuttling and functions...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules HEK293 › p37 regulates VCP/p97 shuttling and functions...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protéines adaptatrices de la transduction du signal › p37 regulates VCP/p97 shuttling and functions...