Assessing the stability and sporicidal efficacy of oxidising disinfectants.
Clostridioides difficile
Detergent
Environmental contamination
Healthcare-associated infection
Oxidising disinfectant
Journal
The Journal of hospital infection
ISSN: 1532-2939
Titre abrégé: J Hosp Infect
Pays: England
ID NLM: 8007166
Informations de publication
Date de publication:
03 May 2024
03 May 2024
Historique:
received:
19
01
2024
revised:
10
04
2024
accepted:
14
04
2024
medline:
6
5
2024
pubmed:
6
5
2024
entrez:
5
5
2024
Statut:
aheadofprint
Résumé
The role of the healthcare environment in the transmission of clinical pathogens is well established. We investigated the chemical stability and sporicidal efficacy of oxidising disinfectant products in the presence of simulated clean and medical dirty conditions. Performance of chlorine-releasing agents (sodium dichloroisocyanurate, chlorine dioxide and hypochlorous acid) was concentration-dependent, with 1000 ppm chlorine showing reduced stability and efficacy in dirty conditions. In contrast peracetic acid product demonstrated stability and consistently achieved efficacy in dirty conditions. These results have implications for clinical practice, as ineffective environmental decontamination may increase the risk of transmission of pathogens that can cause healthcare-associated infections.
Identifiants
pubmed: 38705474
pii: S0195-6701(24)00151-8
doi: 10.1016/j.jhin.2024.04.010
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024. Published by Elsevier Ltd.
Déclaration de conflit d'intérêts
Declaration of Competing Interest L. Brown, A. Marshall, L. Conway, P. Norville, and J. Clarke are employees of GAMA Healthcare Ltd. J. Otter is a consultant to Biointeractions Ltd, Gama Healthcare Ltd, Ondine Inc, and Spectrum X Ltd; he has given paid talks for 3M, ASP, Bode, Ecolab, and Knowlex.