Maribavir for treatment of cytomegalovirus infection in a liver-transplanted patient.
Humans
Cytomegalovirus Infections
/ drug therapy
Liver Transplantation
/ adverse effects
Antiviral Agents
/ therapeutic use
Ribonucleosides
/ therapeutic use
Benzimidazoles
/ therapeutic use
Male
Middle Aged
Cytomegalovirus
/ isolation & purification
Dichlororibofuranosylbenzimidazole
/ analogs & derivatives
Journal
Ugeskrift for laeger
ISSN: 1603-6824
Titre abrégé: Ugeskr Laeger
Pays: Denmark
ID NLM: 0141730
Informations de publication
Date de publication:
08 Apr 2024
08 Apr 2024
Historique:
medline:
6
5
2024
pubmed:
6
5
2024
entrez:
6
5
2024
Statut:
epublish
Résumé
Cytomegalovirus infection (CMV) can be fatal for organ transplant recipients as shown in this case report. Maribavir is a recently approved drug, which can be used for therapy-refractory CMV infection or when other treatment options cannot be used. The patient in this case report was a CMV-infected liver transplant recipient, who developed a severe erythema and high CMV DNA during valganciclovir therapy. Toxic epidermal necrolysis was suspected. The patient was treated with maribavir, and both CMV DNA and the skin normalised. This case illustrates that maribavir is a useful alternative to other antiviral drugs for CMV infection.
Identifiants
pubmed: 38708697
pii: V11230726
doi: 10.61409/V11230726
pii:
doi:
Substances chimiques
Antiviral Agents
0
maribavir
PTB4X93HE1
Ribonucleosides
0
Benzimidazoles
0
Dichlororibofuranosylbenzimidazole
53-85-0
Types de publication
Case Reports
English Abstract
Journal Article
Langues
dan
Sous-ensembles de citation
IM
Informations de copyright
Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.