Generation of a zebrafish neurofibromatosis model via inducible knockout of
Journal
bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187
Informations de publication
Date de publication:
27 Apr 2024
27 Apr 2024
Historique:
medline:
7
5
2024
pubmed:
7
5
2024
entrez:
7
5
2024
Statut:
epublish
Résumé
Neurofibromatosis Type 2 (NF-2) is a dominantly inherited genetic disorder that results from mutations in the tumor suppressor gene, neurofibromin 2 (NF2) gene. Here, we report the generation of a conditional zebrafish model of neurofibromatosis established by an inducible genetic knockout of
Identifiants
pubmed: 38712289
doi: 10.1101/2024.04.23.590787
pmc: PMC11071375
pii:
doi:
Types de publication
Preprint
Langues
eng