Assessing sleep-related breathing disorders among newly diagnosed rheumatoid and psoriatic arthritis patients: a cross-sectional study.

Obstructive sleep apnea Psoriatic arthritis Rheumatoid arthritis Sleep Hypopnea Sleep apnea syndromes Sleep monitoring Sleep-disordered breathing

Journal

Rheumatology international
ISSN: 1437-160X
Titre abrégé: Rheumatol Int
Pays: Germany
ID NLM: 8206885

Informations de publication

Date de publication:
07 May 2024
Historique:
received: 05 03 2024
accepted: 29 04 2024
medline: 7 5 2024
pubmed: 7 5 2024
entrez: 7 5 2024
Statut: aheadofprint

Résumé

This cross-sectional study aimed to determine the prevalence and risk factors for sleep-related breathing disorders (SRBD) in newly diagnosed, untreated rheumatoid arthritis (RA) and psoriatic arthritis (PsA) patients, and to develop a screening algorithm for early detection. We evaluated newly diagnosed RA or PsA patients using the Epworth Sleepiness Scale (ESS) questionnaire, cardiorespiratory polygraphy (RPG), and clinical and laboratory assessments. Sleep apnea syndrome (SAS) was diagnosed based on pathological RPG findings excessive daytime sleepiness, defined as ESS score above 10. The study included 39 patients (22 RA, 17 PsA) and 23 controls. In RPG, SRBD was identified in 38.5% of arthritis patients compared to 39.1% of controls (p = 1.00), with male gender (p = .004) and age (p < .001) identified as risk factors. Excessive daytime sleepiness was noted in 36.4% of RA patients, 17.6% of PsA patients, and 21.7% of controls. Of the 24 patients diagnosed with SRBD, 41.6% met the criteria for SAS. SAS prevalence was 31.8% among RA patients, 0% in PsA patients, and 13% in controls. A significant association was observed between excessive daytime sleepiness and SRBD (p = .036). Our findings reveal a high prevalence of SRBD in newly diagnosed, untreated RA and PsA patients in ESS and RPG, with excessive daytime sleepiness being a reliable predictor of SRBD. Patients with RA exhibited a higher predisposition to SAS. We therefore suggest incorporating ESS and RPG as screening tools in RA or PsA for early detection and management of SRBD.

Identifiants

pubmed: 38713410
doi: 10.1007/s00296-024-05610-8
pii: 10.1007/s00296-024-05610-8
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s).

Références

Michelsen B, Uhlig T, Sexton J et al (2018) Health-related quality of life in patients with psoriatic and rheumatoid arthritis: data from the prospective multicentre NOR-DMARD study compared with Norwegian general population controls. Ann Rheum Dis 77:1290–1294. https://doi.org/10.1136/annrheumdis-2018-213286
doi: 10.1136/annrheumdis-2018-213286 pubmed: 29875096
Holmqvist M, Ljung L, Askling J (2018) Mortality following new-onset rheumatoid arthritis: has modern Rheumatology had an impact? Ann Rheum Dis 77:85–91. https://doi.org/10.1136/annrheumdis-2017-212131
doi: 10.1136/annrheumdis-2017-212131 pubmed: 28970218
Gerhold K, Richter A, Schneider M et al (2015) Health-related quality of life in patients with long-standing rheumatoid arthritis in the era of biologics: data from the German biologics register RABBIT. Rheumatology (Oxford) 54:1858–1866. https://doi.org/10.1093/rheumatology/kev194
doi: 10.1093/rheumatology/kev194 pubmed: 26001633
Haugeberg G, Lund Nilsen TI, Kavanaugh A et al (2021) Physical and psychosocial burden of psoriatic arthritis: Longitudinal Data from a Population-based study in Norway. Arthritis Care Res (Hoboken) 73:138–145. https://doi.org/10.1002/acr.24412
doi: 10.1002/acr.24412 pubmed: 33242358
Michelsen B, Fiane R, Diamantopoulos AP et al (2015) A comparison of disease burden in rheumatoid arthritis, psoriatic arthritis and axial spondyloarthritis. PLoS ONE 10:e0123582. https://doi.org/10.1371/journal.pone.0123582
doi: 10.1371/journal.pone.0123582 pubmed: 25853482 pmcid: 4390320
Finan PH, Goodin BR, Smith MT (2013) The association of sleep and pain: an update and a path forward. J Pain 14:1539–1552. https://doi.org/10.1016/j.jpain.2013.08.007
doi: 10.1016/j.jpain.2013.08.007 pubmed: 24290442 pmcid: 4046588
Wong ITY, Chandran V, Li S et al (2017) Sleep disturbance in Psoriatic Disease: Prevalence and Associated factors. J Rheumatol 44:1369–1374. https://doi.org/10.3899/jrheum.161330
doi: 10.3899/jrheum.161330 pubmed: 28620064
Westhovens R, van der Elst K, Matthys A et al (2014) Sleep problems in patients with rheumatoid arthritis. J Rheumatol 41:31–40. https://doi.org/10.3899/jrheum.130430
doi: 10.3899/jrheum.130430 pubmed: 24293569
Wolfe F, Michaud K, Li T (2006) Sleep disturbance in patients with rheumatoid arthritis: evaluation by medical outcomes study and visual analog sleep scales. J Rheumatol 33:1942–1951
pubmed: 16960928
Bourguignon C, Labyak SE, Taibi D (2003) Investigating sleep disturbances in adults with rheumatoid arthritis. Holist Nurs Pract 17:241–249. https://doi.org/10.1097/00004650-200309000-00005
doi: 10.1097/00004650-200309000-00005 pubmed: 14596374
Lyne L, Åkerstedt T, Alfredsson L et al (2022) Sleep problems in rheumatoid arthritis over 12 years from diagnosis: results from the Swedish EIRA study. RMD Open 8. https://doi.org/10.1136/rmdopen-2021-001800
An J, Nyarko E, Hamad MA (2019) Prevalence of comorbidities and their associations with health-related quality of life and healthcare expenditures in patients with rheumatoid arthritis. Clin Rheumatol 38:2717–2726. https://doi.org/10.1007/s10067-019-04613-2
doi: 10.1007/s10067-019-04613-2 pubmed: 31134504
Taylor PC, Moore A, Vasilescu R et al (2016) A structured literature review of the burden of illness and unmet needs in patients with rheumatoid arthritis: a current perspective. Rheumatol Int 36:685–695. https://doi.org/10.1007/s00296-015-3415-x
doi: 10.1007/s00296-015-3415-x pubmed: 26746843 pmcid: 4839053
Husni ME, Merola JF, Davin S (2017) The psychosocial burden of psoriatic arthritis. Semin Arthritis Rheum 47:351–360. https://doi.org/10.1016/j.semarthrit.2017.05.010
doi: 10.1016/j.semarthrit.2017.05.010 pubmed: 28802776
Gossec L, de Wit M, Kiltz U et al (2014) A patient-derived and patient-reported outcome measure for assessing psoriatic arthritis: elaboration and preliminary validation of the psoriatic arthritis impact of Disease (PsAID) questionnaire, a 13-country EULAR initiative. Ann Rheum Dis 73:1012–1019. https://doi.org/10.1136/annrheumdis-2014-205207
doi: 10.1136/annrheumdis-2014-205207 pubmed: 24790067
Krajewska-Włodarczyk M, Owczarczyk-Saczonek A, Placek W (2018) Sleep disorders in patients with psoriatic arthritis and psoriasis. Reumatologia 56:301–306. https://doi.org/10.5114/reum.2018.79501
doi: 10.5114/reum.2018.79501 pubmed: 30505012 pmcid: 6263298
Gezer O, Batmaz İ, Sariyildiz MA et al (2017) Sleep quality in patients with psoriatic arthritis. Int J Rheum Dis 20:1212–1218. https://doi.org/10.1111/1756-185X.12505
doi: 10.1111/1756-185X.12505 pubmed: 25363664
Callis Duffin K, Wong B, Horn EJ et al (2009) Psoriatic arthritis is a strong predictor of sleep interference in patients with psoriasis. J Am Acad Dermatol 60:604–608. https://doi.org/10.1016/j.jaad.2008.10.059
doi: 10.1016/j.jaad.2008.10.059 pubmed: 19167780
Haugeberg G, Hoff M, Kavanaugh A et al (2020) Psoriatic arthritis: exploring the occurrence of sleep disturbances, fatigue, and depression and their correlates. Arthritis Res Ther 22:198. https://doi.org/10.1186/s13075-020-02294-w
doi: 10.1186/s13075-020-02294-w pubmed: 32847612 pmcid: 7448431
Duvetorp A, Østergaard M, Skov L et al (2019) Quality of life and contact with healthcare systems among patients with psoriasis and psoriatic arthritis: results from the NORdic PAtient survey of psoriasis and psoriatic arthritis (NORPAPP). Arch Dermatol Res 311:351–360. https://doi.org/10.1007/s00403-019-01906-z
doi: 10.1007/s00403-019-01906-z pubmed: 30868221 pmcid: 6546664
Young T, Palta M, Dempsey J et al (1993) The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328:1230–1235. https://doi.org/10.1056/NEJM199304293281704
doi: 10.1056/NEJM199304293281704 pubmed: 8464434
Veasey SC, Rosen IM (2019) Obstructive sleep apnea in adults. N Engl J Med 380:1442–1449. https://doi.org/10.1056/NEJMcp1816152
doi: 10.1056/NEJMcp1816152 pubmed: 30970189
Milleron O, Pillière R, Foucher A et al (2004) Benefits of obstructive sleep apnoea treatment in coronary artery disease: a long-term follow-up study. Eur Heart J 25:728–734. https://doi.org/10.1016/j.ehj.2004.02.008
doi: 10.1016/j.ehj.2004.02.008 pubmed: 15120882
Parish JM, Somers VK (2004) Obstructive sleep apnea and cardiovascular disease. Mayo Clin Proc 79:1036–1046. https://doi.org/10.4065/79.8.1036
doi: 10.4065/79.8.1036 pubmed: 15301332
Taylor-Gjevre RM, Nair BV, Gjevre JA (2013) Obstructive sleep apnoea in relation to rheumatic disease. Rheumatology (Oxford) 52:15–21. https://doi.org/10.1093/rheumatology/kes210
doi: 10.1093/rheumatology/kes210 pubmed: 22923759
Hirsch M, Carlander B, Vergé M et al (1994) Objective and subjective sleep disturbances in patients with rheumatoid arthritis. A reappraisal. Arthritis Rheum 37:41–49. https://doi.org/10.1002/art.1780370107
doi: 10.1002/art.1780370107 pubmed: 8129763
Mahowald MW, Mahowald ML, Bundlie SR et al (1989) Sleep fragmentation in rheumatoid arthritis. Arthritis Rheum 32:974–983. https://doi.org/10.1002/anr.1780320806
doi: 10.1002/anr.1780320806 pubmed: 2765010
Lavie P, Epstein R, Tzischinsky O et al (1992) Actigraphic measurements of sleep in rheumatoid arthritis: comparison of patients with low back pain and healthy controls. J Rheumatol 19:362–365
pubmed: 1533678
Thakur B, Pathak M, Singh P et al (2021) Prevalence of obstructive sleep apnea among patients with rheumatoid arthritis and its association with age and body mass index: a systematic review and meta-analysis. Int J Rheum Dis 24:1354–1361. https://doi.org/10.1111/1756-185X.14178
doi: 10.1111/1756-185X.14178 pubmed: 34724599
Yang Y-W, Kang J-H, Lin H-C (2012) Increased risk of psoriasis following obstructive sleep apnea: a longitudinal population-based study. Sleep Med 13:285–289. https://doi.org/10.1016/j.sleep.2011.07.018
doi: 10.1016/j.sleep.2011.07.018 pubmed: 22285106
Gupta MA, Simpson FC, Gupta AK (2016) Psoriasis and sleep disorders: a systematic review. Sleep Med Rev 29:63–75. https://doi.org/10.1016/j.smrv.2015.09.003
doi: 10.1016/j.smrv.2015.09.003 pubmed: 26624228
Cohen JM, Jackson CL, Li TY et al (2015) Sleep disordered breathing and the risk of psoriasis among US women. Arch Dermatol Res 307:433–438. https://doi.org/10.1007/s00403-015-1536-4
doi: 10.1007/s00403-015-1536-4 pubmed: 25676527
Aletaha D, Neogi T, Silman AJ et al (2010) 2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League against Rheumatism collaborative initiative. Arthritis Rheum 62:2569–2581. https://doi.org/10.1002/art.27584
doi: 10.1002/art.27584 pubmed: 20872595
Coates LC, Kavanaugh A, Mease PJ et al (2016) Group for Research and Assessment of Psoriasis and Psoriatic Arthritis 2015 treatment recommendations for psoriatic arthritis. Arthritis Rheumatol 68:1060–1071. https://doi.org/10.1002/art.39573
doi: 10.1002/art.39573 pubmed: 26749174
(1999) Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The report of an American Academy of Sleep Medicine Task Force. Sleep 22:667–689
Johns MW (1991) A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep 14:540–545. https://doi.org/10.1093/sleep/14.6.540
doi: 10.1093/sleep/14.6.540 pubmed: 1798888
Chung W-S, Lin C-L (2018) Sleep disorders associated with risk of rheumatoid arthritis. Sleep Breath 22:1083–1091. https://doi.org/10.1007/s11325-018-1639-1
doi: 10.1007/s11325-018-1639-1 pubmed: 29428977
Rundo JV (2019) Obstructive sleep apnea basics. Cleve Clin J Med 86:2–9. https://doi.org/10.3949/ccjm.86.s1.02
doi: 10.3949/ccjm.86.s1.02 pubmed: 31509498
Fouda N, Dayem AA (2014) Obstructive sleep apnea in patients with rheumatoid arthritis: correlation with disease activity and pulmonary function tests. Egypt Rheumatologist 36:165–171. https://doi.org/10.1016/j.ejr.2014.04.002
doi: 10.1016/j.ejr.2014.04.002
Myasoedova E, Gabriel SE (2010) Cardiovascular disease in rheumatoid arthritis: a step forward. Curr Opin Rheumatol 22:342–347. https://doi.org/10.1097/BOR.0b013e3283379b91
doi: 10.1097/BOR.0b013e3283379b91 pubmed: 20164773
Daïen CI, Tubery A, Beurai-Weber M et al (2019) Relevance and feasibility of a systematic screening of multimorbidities in patients with chronic inflammatory rheumatic diseases. Joint Bone Spine 86:49–54. https://doi.org/10.1016/j.jbspin.2018.03.016
doi: 10.1016/j.jbspin.2018.03.016 pubmed: 29654949
Nurmohamed MT, Heslinga M, Kitas GD (2015) Cardiovascular comorbidity in rheumatic diseases. Nat Rev Rheumatol 11:693–704. https://doi.org/10.1038/nrrheum.2015.112
doi: 10.1038/nrrheum.2015.112 pubmed: 26282082
Zahnert T (2011) Schlafbezogene Atmungsstörungen (Sleep related breathing disorders). Laryngorhinootologie 90:691–707. https://doi.org/10.1055/s-0031-1293532
doi: 10.1055/s-0031-1293532 pubmed: 22109707
Chen W-S, Chang Y-S, Chang C-C et al (2016) Management and risk reduction of rheumatoid arthritis in individuals with obstructive sleep apnea: a Nationwide Population-based study in Taiwan. Sleep 39:1883–1890. https://doi.org/10.5665/sleep.6174
doi: 10.5665/sleep.6174 pubmed: 27397567 pmcid: 5020370
Nadeem R, Molnar J, Madbouly EM et al (2013) Serum inflammatory markers in obstructive sleep apnea: a meta-analysis. J Clin Sleep Med 9:1003–1012. https://doi.org/10.5664/jcsm.3070
doi: 10.5664/jcsm.3070 pubmed: 24127144 pmcid: 3778171
Alberti A, Sarchielli P, Gallinella E et al (2003) Plasma cytokine levels in patients with obstructive sleep apnea syndrome: a preliminary study. J Sleep Res 12:305–311. https://doi.org/10.1111/j.1365-2869.2003.00361.x
doi: 10.1111/j.1365-2869.2003.00361.x pubmed: 14633242
Ye J, Liu H, Zhang G et al (2012) The treg/th17 imbalance in patients with obstructive sleep apnoea syndrome. Mediators Inflamm 2012:815308. https://doi.org/10.1155/2012/815308
doi: 10.1155/2012/815308 pubmed: 23345934 pmcid: 3549368
Shen T-C, Hang L-W, Liang S-J et al (2016) Risk of obstructive sleep apnoea in patients with rheumatoid arthritis: a nationwide population-based retrospective cohort study. BMJ Open 6:e013151. https://doi.org/10.1136/bmjopen-2016-013151
doi: 10.1136/bmjopen-2016-013151 pubmed: 27895064 pmcid: 5168499
Winter L, Skowasch D, Weber M, AB0380 PREVALENCE OF SLEEP-RELATED BREATHING DISORDERS IN PATIENTS WITH RHEUMATOID ARTHRITIS, PSORIATIC ARTHRITIS, AND PERIPHERAL SPONDYLOARTHRITIS (062023). In: Scientific Abstracts. BMJ Publishing Group Ltd and European League Against Rheumatism, 1374.1–1374

Auteurs

Simon M Petzinna (SM)

Department of Rheumatology and Clinical Immunology, Clinic of Internal Medicine III, University Hospital Bonn, Bonn, Germany. Simon_Michael.Petzinna@ukbonn.de.
Department of Rheumatology and Clinical Immunology, Clinic of Internal Medicine III, University Hospital of Bonn, Venusberg-Campus 1, 53127, Bonn, Germany. Simon_Michael.Petzinna@ukbonn.de.

Lone Winter (L)

Department of Rheumatology and Clinical Immunology, Clinic of Internal Medicine III, University Hospital Bonn, Bonn, Germany.

Dirk Skowasch (D)

Clinic of Internal Medicine II, University Hospital Bonn, Bonn, Germany.

Carmen Pizarro (C)

Clinic of Internal Medicine II, University Hospital Bonn, Bonn, Germany.

Marcel Weber (M)

Clinic of Internal Medicine II, University Hospital Bonn, Bonn, Germany.

Daniel Kütting (D)

Department of Radiology, University Hospital Bonn, Bonn, Germany.

Charlotte Behning (C)

Institute of Medical Biometry, Informatics and Epidemiology, University Hospital Bonn, Bonn, Germany.

Claus-Jürgen Bauer (CJ)

Department of Rheumatology and Clinical Immunology, Clinic of Internal Medicine III, University Hospital Bonn, Bonn, Germany.

Valentin S Schäfer (VS)

Department of Rheumatology and Clinical Immunology, Clinic of Internal Medicine III, University Hospital Bonn, Bonn, Germany.

Classifications MeSH