Proteomic analysis and Lethality of the venom of Aegaeobuthus nigrocinctus, a scorpion of medical significance in the Middle East.

Aegaeobuthus Middle East Scorpion Venom Venomics

Journal

Acta tropica

ISSN: 1873-6254

Titre abrégé: Acta Trop

Pays: Netherlands

ID NLM: 0370374

Informations de publication

Date de publication:
05 May 2024

Historique:

received: 07 03 2024

revised: 24 04 2024

accepted: 25 04 2024

medline: 8 5 2024

pubmed: 8 5 2024

entrez: 7 5 2024

Statut: aheadofprint

Résumé

The scorpion Aegaeobuthus nigrocinctus inhabits areas in Turkey and the Levant region of the Middle East where severe/lethal envenomings have been reported. Previous research indicated its extreme venom lethality to vertebrates and distinct envenomation syndrome. We report on the composition of A. nigrocinctus venom from Lebanese specimens using nESI-MS/MS, MALDI-TOF MS, SDS-PAGE and RP-HPLC. Venom lethality in mice was also assessed (LD

Identifiants

DOI: 10.1016/j.actatropica.2024.107230 PMID: 38714240

pubmed: 38714240

pii: S0001-706X(24)00112-8

doi: 10.1016/j.actatropica.2024.107230

pii:

doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

Pagination

107230

Informations de copyright

Déclaration de conflit d'intérêts

Declaration of competing interests The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.