European Association of Urology Guidelines on Urological Infections: Summary of the 2024 Guidelines.

Antibiotics Antimicrobial stewardship Complicated urinary tract infections Cystitis Male accessory gland infections Periprocedural antibiotic prophylaxis Pyelonephritis Urinary tract infections Urological infections

Journal

European urology
ISSN: 1873-7560
Titre abrégé: Eur Urol
Pays: Switzerland
ID NLM: 7512719

Informations de publication

Date de publication:
06 May 2024
Historique:
received: 12 03 2024
revised: 18 03 2024
accepted: 28 03 2024
medline: 8 5 2024
pubmed: 8 5 2024
entrez: 7 5 2024
Statut: aheadofprint

Résumé

Urological infections significantly impact the wellbeing and quality of life of individuals owing to their widespread occurrence and diverse clinical manifestations. The objective of the guidelines panel was to provide evidence-based guidance on the diagnosis, treatment, and prevention of urinary tract infections (UTIs) and male accessory-gland infections, while addressing crucial public health aspects related to infection control and antimicrobial stewardship. For the 2024 guidelines on urological infections, new and relevant evidence was identified, collated, and appraised via a structured assessment of the literature. Databases searched included Medline, EMBASE, and the Cochrane Libraries. Recommendations within the guidelines were developed by the panel to prioritise clinically important care decisions. The strength of each recommendation was determined according to a balance between desirable and undesirable consequences of alternative management strategies, the quality of the evidence (including the certainty of estimates), and the nature and variability of patient values and preferences. Key recommendations emphasise the importance of a thorough medical history and physical examination for patients with urological infections. The guidelines stress the role of antimicrobial stewardship to combat the rising threat of antimicrobial resistance, providing recommendations for antibiotic selection, dosing, and duration on the basis of the latest evidence. This overview of the 2024 EAU guidelines offers valuable insights into managing urological infections and are designed for effective integration into clinical practice. The European Association of Urology has issued an updated guideline on urological infections. The guidelines provide recommendations for diagnosis, treatment, and prevention, with a particular focus on minimising antibiotic use because of the increasing global threat of antimicrobial resistance.

Sections du résumé

BACKGROUND AND OBJECTIVE OBJECTIVE
Urological infections significantly impact the wellbeing and quality of life of individuals owing to their widespread occurrence and diverse clinical manifestations. The objective of the guidelines panel was to provide evidence-based guidance on the diagnosis, treatment, and prevention of urinary tract infections (UTIs) and male accessory-gland infections, while addressing crucial public health aspects related to infection control and antimicrobial stewardship.
METHODS METHODS
For the 2024 guidelines on urological infections, new and relevant evidence was identified, collated, and appraised via a structured assessment of the literature. Databases searched included Medline, EMBASE, and the Cochrane Libraries. Recommendations within the guidelines were developed by the panel to prioritise clinically important care decisions. The strength of each recommendation was determined according to a balance between desirable and undesirable consequences of alternative management strategies, the quality of the evidence (including the certainty of estimates), and the nature and variability of patient values and preferences.
KEY FINDINGS AND LIMITATIONS UNASSIGNED
Key recommendations emphasise the importance of a thorough medical history and physical examination for patients with urological infections. The guidelines stress the role of antimicrobial stewardship to combat the rising threat of antimicrobial resistance, providing recommendations for antibiotic selection, dosing, and duration on the basis of the latest evidence.
CONCLUSIONS AND CLINICAL IMPLICATIONS CONCLUSIONS
This overview of the 2024 EAU guidelines offers valuable insights into managing urological infections and are designed for effective integration into clinical practice.
PATIENT SUMMARY RESULTS
The European Association of Urology has issued an updated guideline on urological infections. The guidelines provide recommendations for diagnosis, treatment, and prevention, with a particular focus on minimising antibiotic use because of the increasing global threat of antimicrobial resistance.

Identifiants

pubmed: 38714379
pii: S0302-2838(24)02263-2
doi: 10.1016/j.eururo.2024.03.035
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024 The Author(s). Published by Elsevier B.V. All rights reserved.

Auteurs

Jennifer Kranz (J)

Department of Urology and Pediatric Urology, RWTH Aachen University, Aachen, Germany; Department of Urology and Kidney Transplantation, Martin-Luther-University, Halle, Germany. Electronic address: jkranz@ukaachen.de.

Riccardo Bartoletti (R)

Department of Translational Research and New Technologies, University of Pisa, Pisa, Italy.

Franck Bruyère (F)

Department of Urology, CHRU Bretonneau, Tours, France; Université Francois Rabelais, PRES Centre Val de Loire, Tours, France.

Tommaso Cai (T)

Department of Urology, Santa Chiara, Regional Hospital, Trento, Italy.

Suzanne Geerlings (S)

Department of Internal Medicine, Amsterdam Institute for Infection and Immunity, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands; Amsterdam University Medical Center, Amsterdam, The Netherlands.

Bela Köves (B)

Department of Urology, University of Szeged, Szeged, Hungary.

Sören Schubert (S)

Max von Pettenkofer Institute, Faculty of Medicine, LMU Munich, Munich, Germany.

Adrian Pilatz (A)

Department of Urology, Pediatric Urology and Andrology, Justus-Liebig-University Giessen, Giessen, Germany.

Rajan Veeratterapillay (R)

Freeman Hospital, Newcastle Upon Tyne, UK.

Florian M E Wagenlehner (FME)

Department of Urology, Pediatric Urology and Andrology, Justus-Liebig-University Giessen, Giessen, Germany.

Kathrin Bausch (K)

Department of Urology, University Hospital Basel, University of Basel, Basel, Switzerland.

Wout Devlies (W)

Department of Urology, UZ Leuven, Leuven, Belgium.

József Horváth (J)

BKMK SZTE ÁOK Okt. Kh. Urológiai Osztálya, Kecskemét, Hungary.

Lorenz Leitner (L)

Department of Neuro-Urology, Balgrist University Hospital, University of Zürich, Zürich, Switzerland.

Guglielmo Mantica (G)

IRCCS Ospedale Policlinico San Martino, Genova, Italy.

Tunde Mezei (T)

Department of Urology, Telemark Hospital, Skien, Norway.

Emma J Smith (EJ)

European Association of Urology Guidelines Office, Arnhem, The Netherlands.

Gernot Bonkat (G)

alta Uro AG, Merian Iselin Klinik, Center of Biomechanics & Calorimetry, University of Basel, Basel, Switzerland.

Classifications MeSH