Efficacy of multivitamin support following bariatric surgery in patients with obesity: a prospective observational study.

Humans Middle Aged Female Adult Male Bariatric Surgery Vitamins / therapeutic use Prospective Studies Aged Treatment Outcome Obesity, Morbid / surgery Dietary Supplements Weight Loss Micronutrients / administration & dosage

Bariatric surgery Micronutrients Multivitamin support Obesity

Journal

Eating and weight disorders : EWD

ISSN: 1590-1262

Titre abrégé: Eat Weight Disord

Pays: Germany

ID NLM: 9707113

Informations de publication

Date de publication:
07 May 2024

Historique:

received: 30 11 2023

accepted: 02 04 2024

medline: 8 5 2024

pubmed: 8 5 2024

entrez: 7 5 2024

Statut: epublish

Résumé

Bariatric surgery (BS), an effective treatment for severe obesity and its comorbidities, may result in micronutrient and vitamin deficiencies. This monocentric prospective observational study aimed at evaluating the efficacy of a specifically designed vitamin/mineral formula (Bariatrifast, BIOITALIA S.r.l., Italy) for preventing and treating micronutrient deficiencies in patients submitted to BS. Twenty patients with severe obesity (mean weight and BMI: 123.5 kg (range 88-174) and 43.3 kg/m All patients achieved a significant weight loss (mean - 34.7 ± 11.8 kg). No deficiencies of various vitamins/micronutrients were detected during the entire study period. The serum concentrations of vitamin B12, 25-OH Vitamin D and folic acid increased over the follow-up period compared with V0 (mean increase 243 ng/L, 23 µg /L, 8 µg/L, respectively). Compared to RYGB, patients who underwent sleeve gastrectomy showed higher levels of 25-OH vitamin D at V2, V3 and V4 (all p < 0.05), and higher levels of Vitamin B12 and folic acid at V4 (p < 0.05 and p < 0.005, respectively). No adverse events were reported. Following VSG or RYGB, Bariatrifast administration was associated with normal values of essential micronutrients, and it was well-tolerated without evidence of gastrointestinal side effects. Clinical Trial Registration ClinicalTrials.gov, identifiers NCT06152965.

Identifiants

DOI: 10.1007/s40519-024-01655-7 PMID: 38714632

pubmed: 38714632

doi: 10.1007/s40519-024-01655-7

pii: 10.1007/s40519-024-01655-7

doi:

Substances chimiques

Vitamins 0

Micronutrients 0

Banques de données

ClinicalTrials.gov

['NCT06152965']

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

Pagination

Informations de copyright

Références

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