Improvement of Quality of Life after Surgical Treatment of Patients with MRONJ: A Prospective Analysis Using the SF-12 and OHIP-14 Questionnaires.
Journal
International journal of dentistry
ISSN: 1687-8728
Titre abrégé: Int J Dent
Pays: Egypt
ID NLM: 101524183
Informations de publication
Date de publication:
2024
2024
Historique:
received:
22
07
2023
revised:
16
02
2024
accepted:
16
04
2024
medline:
8
5
2024
pubmed:
8
5
2024
entrez:
8
5
2024
Statut:
epublish
Résumé
Medication-related osteonecrosis of the jaw (MRONJ) is a rare, serious, and debilitating disease of unknown cause that can be associated with significant health-related quality of life (HRQOL) impairment. Hematological disease is characterized by a nonhealing exposed jawbone in patients with a history of antiresorptive or antiangiogenic agent use without radiation exposure to the head or neck. A total of 27 patients considered in the study had a total of 42 MRONJ lesions, corresponding to a mean of 1.56 necroses per patient. MRONJ lesions were downstaged in 85% of the patients. HRQOL was evaluated with the SF-12 questionnaire. Significant improvements were found in six of the eight categories (General Health ( With completed surgical therapy, improvements in HRQOL and OHRQOL are measurable.
Sections du résumé
Background
UNASSIGNED
Medication-related osteonecrosis of the jaw (MRONJ) is a rare, serious, and debilitating disease of unknown cause that can be associated with significant health-related quality of life (HRQOL) impairment. Hematological disease is characterized by a nonhealing exposed jawbone in patients with a history of antiresorptive or antiangiogenic agent use without radiation exposure to the head or neck.
Results
UNASSIGNED
A total of 27 patients considered in the study had a total of 42 MRONJ lesions, corresponding to a mean of 1.56 necroses per patient. MRONJ lesions were downstaged in 85% of the patients. HRQOL was evaluated with the SF-12 questionnaire. Significant improvements were found in six of the eight categories (General Health (
Conclusion
UNASSIGNED
With completed surgical therapy, improvements in HRQOL and OHRQOL are measurable.
Identifiants
pubmed: 38715871
doi: 10.1155/2024/4435791
pmc: PMC11074825
doi:
Types de publication
Journal Article
Langues
eng
Pagination
4435791Informations de copyright
Copyright © 2024 Georg Hoene et al.
Déclaration de conflit d'intérêts
The authors have declared that no conflicts of interest exist.