Advances in ultra-high-pressure and multi-dimensional liquid chromatography instrumentation and workflows.
2D‐LC
UHPLC
spatial three‐dimensional liquid chromatography
two‐dimensional liquid chromatography
Journal
Analytical science advances
ISSN: 2628-5452
Titre abrégé: Anal Sci Adv
Pays: Germany
ID NLM: 9918334986206676
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
received:
21
01
2021
accepted:
01
03
2021
medline:
16
3
2021
pubmed:
16
3
2021
entrez:
8
5
2024
Statut:
epublish
Résumé
The present contribution discusses recent advances in ultra-high-pressure liquid chromatography (UHPLC) and multi-dimensional liquid chromatography (MDLC) technology. First, new developments in UHPLC column technology and system design are highlighted. The latter includes a description of a novel injector concept enabling method speed-up, emerging detectors, and instrument diagnostics approaches. Next, online MDLC workflows are reviewed and advances in modulation technology are highlighted. Finally, key applications published in 2020 are reviewed.
Identifiants
pubmed: 38716447
doi: 10.1002/ansa.202100007
pii: ANSA202100007
pmc: PMC10989561
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
171-192Informations de copyright
© 2021 The Authors. Analytical Science Advances published by Wiley‐VCH GmbH.