The Impact of Infant Bacille Calmette-Guérin Vaccination on the Immunogenicity of Other Vaccines: A Randomized Exploratory Study.


Journal

The Pediatric infectious disease journal
ISSN: 1532-0987
Titre abrégé: Pediatr Infect Dis J
Pays: United States
ID NLM: 8701858

Informations de publication

Date de publication:
08 May 2024
Historique:
medline: 8 5 2024
pubmed: 8 5 2024
entrez: 8 5 2024
Statut: aheadofprint

Résumé

The effect of the Bacille Calmette-Guérin (BCG) vaccine on the immunogenicity of separately administered serogroup C meningococcal vaccine and other vaccinations was examined in 28 infants randomized to receive BCG at age ≤7 days, at 3 months or after study completion. Immunogenicity of the serogroup C meningococcal vaccine and other routine vaccines might be improved when BCG is administered in early infancy.

Identifiants

pubmed: 38717982
doi: 10.1097/INF.0000000000004373
pii: 00006454-990000000-00860
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

The authors have no conflicts of interest to disclose.

Références

Higgins JP, Soares-Weiser K, Lopez-Lopez JA, et al. Association of BCG, DTP, and measles containing vaccines with childhood mortality: systematic review. BMJ. 2016;355:i5170.
Arts RJW, Moorlag S, Novakovic B, et al. BCG vaccination protects against experimental viral infection in humans through the induction of cytokines associated with trained immunity. Cell Host Microbe. 2018;23:89–100 e5.
Giamarellos-Bourboulis EJ, Tsilika M, Moorlag S, et al. Activate: randomized clinical trial of BCG vaccination against infection in the elderly. Cell. 2020;183:315–323.e9.
Fu W, Ho P-C, Liu C-L, et al. Reconcile the debate over protective effects of BCG vaccine against COVID-19. Sci Rep. 2021;11:8356.
Pittet LF, Messina NL, Orsini F, et al.; BRACE Trial Consortium Group. Randomized trial of BCG vaccine to protect against Covid-19 in health care workers. N Engl J Med. 2023;388:1582–1596.
Noble CCA, Messina NL, Pittet LF, et al. Interpreting the results of trials of BCG vaccination for protection against COVID-19. J Infect Dis. 2023;228:1467–1478.
Pichichero ME. Protein carriers of conjugate vaccines: characteristics, development, and clinical trials. Hum Vaccin Immunother. 2013;9:2505–2523.
Frasch CE, Borrow R, Donnelly J. Bactericidal antibody is the immunologic surrogate of protection against meningococcal disease. Vaccine. 2009;27:B112–B116.
Gheesling LL, Carlone GM, Pais LB, et al. Multicenter comparison of Neisseria meningitidis serogroup C anti-capsular polysaccharide antibody levels measured by a standardized enzyme-linked immunosorbent assay. J Clin Microbiol. 1994;32:1475–1482.
Maslanka SE, Gheesling LL, Libutti DE, et al. Standardization and a multilaboratory comparison of Neisseria meningitidis serogroup A and C serum bactericidal assays. the multilaboratory study group. Clin Diagn Lab Immunol. 1997;4:156–167.

Auteurs

Alexander Maytum (A)

From the Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom.

David Porter (D)

From the Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom.

Philip de Whalley (P)

From the Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom.

Amber Thompson (A)

From the Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom.

Emma Plested (E)

From the Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom.

Simon Kerridge (S)

From the Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom.

Xinxue Liu (X)

From the Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom.

Gaby Smits (G)

National Institute of Public Health and the Environment, Centre for Infectious Disease Control, Bilthoven, The Netherlands.

Fiona van der Klis (F)

National Institute of Public Health and the Environment, Centre for Infectious Disease Control, Bilthoven, The Netherlands.

Matthew D Snape (MD)

From the Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom.

Elizabeth Clutterbuck (E)

From the Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom.

Andrew J Pollard (AJ)

From the Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom.

Classifications MeSH