Unveiling the Dark Side of Datura in Pediatric Poisoning With Insights From Jordanian Experience: A Retrospective Clinical Study.
Journal
Pediatric emergency care
ISSN: 1535-1815
Titre abrégé: Pediatr Emerg Care
Pays: United States
ID NLM: 8507560
Informations de publication
Date de publication:
09 May 2024
09 May 2024
Historique:
medline:
9
5
2024
pubmed:
9
5
2024
entrez:
8
5
2024
Statut:
aheadofprint
Résumé
Datura stramonium, jimsonweed, is a toxic plant with hallucinogenic properties. Although there are many studies on Datura poisoning, none reported cases in Jordan. This study offers a comprehensive review on D. stramonium ingestion, covering its epidemiology, clinical presentation, and treatment. We aimed to provide better understanding of the factors for Datura ingestion, identify prevention and management strategies, and address research challenges. This study adopted a retrospective review design to evaluate the cases of Datura poisoning in Al Karak, province of Jordan during the spring of 2022. Data collected from medical records, toxicology databases, and consultation records were analyzed using descriptive statistics. The common symptoms of Datura poisoning included agitation, mydriasis, and tachycardia. The management approaches comprised supportive care, administration of Diazepam for agitation, and, in some cases, neostigmine to counteract anticholinergic effects. Understanding the risks associated with D. stramonium poisoning and implementing effective prevention and management strategies are crucial. This study highlights the importance of recognizing Datura poisoning as a potential diagnosis in children presenting with unexplained anticholinergic symptoms or agitation to the emergency room.
Identifiants
pubmed: 38718809
doi: 10.1097/PEC.0000000000003189
pii: 00006565-990000000-00460
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.
Références
Avery A, Satina S, Rietsema J. The genus Datura. Foreword and biographical sketch by Edmund W. Sinnott. New York, NY: Ronald Press Co.; 1959.
"Datura metel". plants.ces.ncsu.edu. Retrieved 17 January 2016.
Trancă SD, Szabo R, Cociş M. Acute poisoning due to ingestion of Datura stramonium—a case report. Rom J Anaesth Intensive Care. 2017;24:65–68.
Fatur K. “Hexing herbs” in ethnobotanical perspective: a historical review of the uses of anticholinergic Solanaceae plants in Europe. Econ Bot. 2020;74:140–158.
Kennedy DO. The Deliriants—The Nightshade (Solanaceae) Family. Plants and the Human Brain. New York, NY: Oxford University Press; 2014:131–137.
Hansen HA. The Witch's Garden. Unity Press; 1978. ISBN: 9780913300473.
Rätsch C. The Encyclopedia of Psychoactive Plants: Ethnopharmacology and Its Applications. Rochester, Vermont, USA: Park Street Press; 2005.
Fatur K, Kreft S. Common anticholinergic solanaceaous plants of temperate Europe—a review of intoxications from the literature (1966–2018). Toxicon. 2020;177:52–88.
Goetz R, Siegel E, Scaglione J, et al. Suspected moonflower intoxication—Ohio, 2002. Morb Mortal Wkly Rep CDC. 52:788–791.
Leinwand D. (2006). Jimson weed users chase high all the way to hospital. USA Today. Available at: https://www.usatoday.com/news/nation/2006-11-01-jimson_x.htm. Accessed February 15, 2009.
Pennachio M, Jefferson L, Havens K. Uses and Abuses of Plant-Derived Smoke: Its Ethnobotany As Hallucinogen, Perfume, Incense, and Medicine. Oxford, United Kingdom: Oxford University Press; 2010.
Mutebi RR, Ario AR, Nabatanzi M, et al. Large outbreak of jimsonweed (Datura stramonium) poisoning due to consumption of contaminated humanitarian relief food: Uganda, March–April 2019. BMC Public Health. 2022;22:623.
Gaire BP, Subedi L. A review on the pharmacological and toxicological aspects of Datura stramonium L. J Integr Med. 2013;11:73–79.
Doan UV, Wu ML, Phua DH, et al. Datura and Brugmansia plants related antimuscarinic toxicity: an analysis of poisoning cases reported to the Taiwan poison control center. Clin Toxicol (Phila). 2019;57:246–253.
Krenzelok EP. Aspects of Datura poisoning and treatment. Clin Toxicol (Phila). 2010;48:104–110.
Wilden J, Rapeport D. Presumed central anticholinergic syndrome from inadvertent intravenous hyoscine hydrobromide (scopolamine) injection. Anaesth Intensive Care. 2004;32:419–422.
Kanchan T, Atreya A. Datura: the roadside poison. Wilderness Environ Med. 2016;27:442–443.
Chan K. Jimson weed poisoning—a case report. Perm J. 2002;6:28–30.
Gerson R, Malas N, Feuer V, et al. Best practices for evaluation and treatment of agitated children and adolescents (BETA) in the emergency department: consensus statement of the American Association for Emergency Psychiatry. West J Emerg Med. 2019;20:409–418.
Bronstein AC, Spyker DA, Cantilena LR Jr., et al. 2011 Annual report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 29th annual report. Clin Toxicol. 2012;50:911–1164.
Spina SP, Taddei C, De Ferrari L, et al. Plant poisonings: a case series. Int J Emerg Med. 2013;6:1–3.
Sharma V, Singla R, Jindal AK. Acute Datura stramonium poisoning: a case report and review of literature. Indian J Crit Care Med. 2013;17:253–255.
Patel TK, Patel PB, Shah PG, et al. A study on clinical profile of Datura poisoning in tertiary care hospital. Int J Med Sci Public Health. 2016;5:239–242.
Das KK, Sharma A, Kumar N, et al. Datura poisoning: an unusual presentation. Toxicol Int. 2012;19:288–289.
Sharma B, Singh H, Sharma V, et al. An epidemiological study of poisoning cases in Western Rajasthan. Toxicol Int. 2011;18:65–66.
Subedi B, Manandhar M, Pathak OK, et al. Datura poisoning: a case report. J Chitwan Med Coll. 2016;6:52–54.
Ahmad I, Shabbir A, Malik RN. A review on phytochemistry, ethnobotany and pharmacological aspects of genus Datura L. J Integr Med. 2017;15:83–99.
Bilgin TE, Caglar S, Turgut S. An unusual case of Datura stramonium intoxication: a report of three cases. Turk J Emerg Med. 2016;16:80–82.
Khaja M, Shafiullah M, Khalid M, et al. Cardiac dysrhythmias following Datura stramonium ingestion. J Coll Physicians Surg Pak. 2016;26:626–627.
Verma SK, Kumar V, Gautam V, et al. A prospective study of clinical profile of patients of Datura stramonium poisoning and their outcome. Int J Med Toxicol Forensic Med. 2014;4:51–55.
Gümüştaş Ş, Balkan Ş, Yapalı S, et al. Anticholinergic syndrome following Datura stramonium ingestion: a case report. Turk J Emerg Med. 2016;16:120–122.
Çakır M, Aktas G, Yılmaz F. A case of Datura stramonium poisoning associated with recreational use. J Forensic Sci. 2021;66:1504–1507.
Kumar P, Chaudhary A, Aggarwal A, et al. Datura intoxication: a case series and review of literature. Indian J Crit Care Med. 2020;24:820–823.
Patel M, Patel K, Patel PB, et al. Datura stramonium poisoning: a case series and review of literature. J Family Med Prim Care. 2019;8:798–802.