Intestinal Transplantation: Include the Spleen with Intestinal Graft?

Humans Intestines / transplantation Spleen / transplantation Graft vs Host Disease / prevention & control Graft Rejection / prevention & control Organ Transplantation / methods Pancreas Transplantation / methods
Acute cellular rejection Antibody-mediated rejection GVHD Multivisceral transplant Spleen transplantation Transplant immunology

Journal

Gastroenterology clinics of North America
ISSN: 1558-1942
Titre abrégé: Gastroenterol Clin North Am
Pays: United States
ID NLM: 8706257

Informations de publication

Date de publication:
Jun 2024
Historique:
medline: 9 5 2024
pubmed: 9 5 2024
entrez: 8 5 2024
Statut: ppublish

Résumé

The traditional procedure for multivisceral transplant (MVT) is to transplant the stomach, pancreas, intestine, and liver en bloc. During surgery, the native spleen is routinely removed from the recipient, and it usually creates more space in the abdomen to insert the allogeneic graft. Thus, recipients often become asplenic after MVT. Considering all of the risks and benefits, we advocate that temporary transplant of the donor spleen could be the best option for MVT recipients; it could potentially reduce the rate of intestinal allograft rejection without increasing the risk for graft-versus-host disease.

Identifiants

DOI: 10.1016/j.gtc.2023.12.002 PMID: 38719378
pubmed: 38719378
pii: S0889-8553(23)00125-5
doi: 10.1016/j.gtc.2023.12.002
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

281-288

Informations de copyright

Copyright © 2024 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure The authors declare no conflicts of interest.

Auteurs

Rei Matsumoto (R)

Center for Liver Disease and Transplantation, Columbia University Irving Medical Center.

Tomoaki Kato (T)

Center for Liver Disease and Transplantation, Columbia University Irving Medical Center. Electronic address: tk2388@columbia.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Intestinal Transplantation: Include the Spleen...
questionsmedicales.fr › Système digestif › Tube digestif › Intestins › Intestinal Transplantation: Include the Spleen...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Système lymphatique › Tissu lymphoïde › Rate › Intestinal Transplantation: Include the Spleen...
questionsmedicales.fr › Maladies du système immunitaire › Maladie du greffon contre l'hôte › Intestinal Transplantation: Include the Spleen...
questionsmedicales.fr › Phénomènes du système immunitaire › Immunologie en transplantation › Réaction de l'hôte contre le greffon › Rejet du greffon › Intestinal Transplantation: Include the Spleen...
questionsmedicales.fr › Procédures de chirurgie opératoire › Transplantation › Transplantation d'organe › Intestinal Transplantation: Include the Spleen...
questionsmedicales.fr › Procédures de chirurgie opératoire › Transplantation › Transplantation d'organe › Transplantation pancréatique › Intestinal Transplantation: Include the Spleen...