A Case of Non-Seminomatous Germ Cell Tumor Complicated by Tumor Thrombus in an Active Duty Soldier.


Journal

Military medicine
ISSN: 1930-613X
Titre abrégé: Mil Med
Pays: England
ID NLM: 2984771R

Informations de publication

Date de publication:
09 May 2024
Historique:
received: 25 10 2023
revised: 05 03 2024
accepted: 02 04 2024
medline: 9 5 2024
pubmed: 9 5 2024
entrez: 9 5 2024
Statut: aheadofprint

Résumé

Testicular malignancies commonly affect adolescent and young adult males. Although they tend to respond well to cisplatin-based chemotherapy with excellent overall survival, complications such as inferior vena cava tumor thrombus are rare and can be associated with high morbidity and mortality. We present a case of tumor thrombus in a 21-year-old active duty male with a newly diagnosed stage IIIB non-seminomatous germ cell tumor presenting with extensive left lower extremity swelling. Ultrasound with Doppler was notable for significant thrombus of the left common femoral, femoral, and popliteal vein. Computed tomography imaging revealed extensive thrombus of the inferior vena cava, left iliac veins, and left gonadal vein with sparing of the left renal vein. Endovascular thrombectomy was performed with pathologic analysis confirming the presence of malignant cells consistent with tumor thrombus. The patient continued subsequent non-seminomatous germ cell tumor treatment without complications.

Identifiants

pubmed: 38720563
pii: 7667474
doi: 10.1093/milmed/usae174
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© The Association of Military Surgeons of the United States 2024. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site–for further information please contact journals.permissions@oup.com.

Auteurs

Matthew Grossmann (M)

Department of Internal Medicine, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA.

Chung-Ting J Kou (CJ)

Department of Hematology/Oncology, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA.

Breanne Vergonet (B)

Department of Pathology, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA.

Matthew Soderstrom (M)

Department of Internal Medicine, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA.

Matthew J Rendo (MJ)

Department of Hematology/Oncology, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA.

Lauren E Lee (LE)

Department of Hematology/Oncology, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA.

Classifications MeSH