Perception of the impact of intravenous biological treatment on the work and professional environment in patients with inflammatory bowel disease.

Percepción del impacto del tratamiento biológico endovenoso sobre el ámbito laboral y personal en pacientes con enfermedad inflamatoria intestinal.
Administration route Biologics Biológicos Enfermedad inflamatoria intestinal Inflammatory bowel disease Infliximab Vía de administración

Journal

Gastroenterologia y hepatologia
ISSN: 0210-5705
Titre abrégé: Gastroenterol Hepatol
Pays: Spain
ID NLM: 8406671

Informations de publication

Date de publication:
07 May 2024
Historique:
received: 29 01 2024
revised: 08 04 2024
accepted: 12 04 2024
pubmed: 10 5 2024
medline: 10 5 2024
entrez: 9 5 2024
Statut: aheadofprint

Résumé

In the treatment of inflammatory bowel disease (IBD), we have biologic therapies administered intravenously and subcutaneously. Recently, some drugs can be administered by either of these routes. The real impact that intravenous administration has on the perception of the disease and the personal and work life of the patient is unknown. All IBD patients receiving intravenous infliximab treatment for at least 6 months were anonymously invited to participate. They were provided with a specific structured questionnaire with visual analogue scales (0-10) at two reference centers in the Barcelona area. A total of 90 patients with a median age of 45 years (36-56) and a median infliximab treatment duration of 48 months (24-84) were included. The visit and therapy with infliximab in the day hospital were globally well evaluated (9, IQR 7-10). 78% of patients combined day hospital stays with other activities (26% employment). The personal impact was generally low (4, IQR 0-5.8), but the patient's job was threatened in 43% of patients on intensified treatment. The intravenous administration of biologic drugs on an outpatient basis is highly satisfactory among IBD patients. The impact on the work sphere appears to be more pronounced than on the personal sphere, an aspect that should be considered in shared decision-making with the patient.

Identifiants

pubmed: 38723767
pii: S0210-5705(24)00151-1
doi: 10.1016/j.gastrohep.2024.502193
pii:
doi:

Types de publication

Journal Article

Langues

eng spa

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024 Elsevier España, S.L.U. All rights reserved.

Auteurs

Carlos González-Muñoza (C)

Servicio de Patología Digestiva, Hospital Santa Creu i Sant Pau, Barcelona, España.

Cristina Gely (C)

Servicio de Patología Digestiva, Hospital Santa Creu i Sant Pau, Barcelona, España.

Jordi Gordillo (J)

Servicio de Patología Digestiva, Hospital Santa Creu i Sant Pau, Barcelona, España.

Margalida Calafat (M)

Servicio de Aparato Digestivo, Hospital Universitari Germans Trias i Pujol, Barcelona, España; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), España.

Federico Bertoletti (F)

Servicio de Patología Digestiva, Hospital Santa Creu i Sant Pau, Barcelona, España.

Fiorella Cañete (F)

Servicio de Aparato Digestivo, Hospital Universitari Germans Trias i Pujol, Barcelona, España; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), España.

Míriam Mañosa (M)

Servicio de Aparato Digestivo, Hospital Universitari Germans Trias i Pujol, Barcelona, España; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), España.

Alberto López-Faba (A)

Servicio de Patología Digestiva, Hospital Santa Creu i Sant Pau, Barcelona, España.

Paola Torres (P)

Servicio de Aparato Digestivo, Hospital Universitari Germans Trias i Pujol, Barcelona, España.

Eugeni Domènech (E)

Servicio de Aparato Digestivo, Hospital Universitari Germans Trias i Pujol, Barcelona, España; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), España; Departamento de Medicina, Universitat Autònoma de Barcelona, Barcelona, España.

Esther Garcia-Planella (E)

Servicio de Patología Digestiva, Hospital Santa Creu i Sant Pau, Barcelona, España. Electronic address: egarciapl@santpau.cat.

Classifications MeSH