A fatal snakebite envenomation due to King cobra (Ophiophagus hannah) in the Eastern Visayas, Philippines.

Antivenom King cobra Neglected tropical diseases Neurotoxicity Ophiophagus hannah Respiratory resuscitation

Journal

Toxicon : official journal of the International Society on Toxinology
ISSN: 1879-3150
Titre abrégé: Toxicon
Pays: England
ID NLM: 1307333

Informations de publication

Date de publication:
07 May 2024
Historique:
received: 11 03 2024
revised: 30 04 2024
accepted: 07 05 2024
medline: 10 5 2024
pubmed: 10 5 2024
entrez: 9 5 2024
Statut: aheadofprint

Résumé

This report details a documented case of fatal King cobra (Ophiophagus hannah) envenomation in the Philippines. A 46-year-old woman from a mountainous town Leyte was bitten on her left thigh by a snake. Despite receiving prompt medical attention, including administration of fluids and oxygen, she went into arrest and succumbed within 2.5 hours of the bite. Inadequate pre-hospital care, including endotracheal intubation and assisted ventilation, highlights a notable gap in emergency medical services. Photographic evidence, verified by a herpetologist, confirmed the involvement of a King cobra, with venom presenting with a swift and lethal systemic effect that led to the patient's demise, despite minimal local manifestations. This incident accentuates the urgent need for accessible, effective antivenom and improved snakebite management protocols in the Philippines. It also calls for heightened awareness and preparedness among pre-hospital healthcare providers and the public, alongside advocating for more research into snakebite envenomation.

Identifiants

pubmed: 38723869
pii: S0041-0101(24)00323-4
doi: 10.1016/j.toxicon.2024.107751
pii:
doi:

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

107751

Informations de copyright

Copyright © 2024. Published by Elsevier Ltd.

Déclaration de conflit d'intérêts

Declaration of Competing Interest ☒ The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. ☐The authors declare the following financial interests/personal relationships which may be considered as potential competing interests:

Auteurs

Rustan Arrieta (R)

Department of Emergency Medicine, Eastern Visayas Medical Center, Tacloban, Philippines.

Yoshihiro Aoki (Y)

Coordination Office for Emergency Medicine and International Response, Acute and Critical Care Center, Nagasaki University Hospital, Nagasaki, Japan; School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan. Electronic address: yaoki-hki@umin.ac.jp.

Mariedel A Tan (MA)

Poison Control Center, Eastern Visayas Medical Center, Tacloban, Philippines.

Mardie S Sarsalijo (MS)

Poison Control Center, Eastern Visayas Medical Center, Tacloban, Philippines.

Marvin Jay Sarmiento (MJ)

Philippine Toxinology Society, Inc; Crocodylus Porosus Philippines Inc., Microbiological Laboratory Inc. Evangelista, Makati City, Philippines; University of the Philippines Los Banos, Los Banos, Philippines.

Jonathan Paghubasan (J)

Department of Emergency Medicine, Eastern Visayas Medical Center, Tacloban, Philippines.

Patrick Joseph Tiglao (PJ)

Philippine Toxinology Society, Inc; Department of Emergency Medicine, University of the Philippines-Philippine General Hospital, Manila, Philippines.

Ken Yoshimura (K)

Japan Snake Institute, Gunma, Japan.

Atsushi Sakai (A)

Japan Snake Institute, Gunma, Japan.

Lourdes C Agosto (LC)

Poison Control Center, Eastern Visayas Medical Center, Tacloban, Philippines.

Classifications MeSH