Validation of the Individualized Metabolic Surgery score in predicting long-term remission of diabetes after duodenal switch-type procedures.

IMS SADI‐S SADS duodenal switch type 2 diabetes

Journal

Diabetes, obesity & metabolism
ISSN: 1463-1326
Titre abrégé: Diabetes Obes Metab
Pays: England
ID NLM: 100883645

Informations de publication

Date de publication:
09 May 2024
Historique:
revised: 13 04 2024
received: 20 03 2024
accepted: 23 04 2024
medline: 10 5 2024
pubmed: 10 5 2024
entrez: 9 5 2024
Statut: aheadofprint

Résumé

To validate the Individualized Metabolic Surgery (IMS) score and assess long-term remission of type 2 diabetes (T2D) after duodenal switch (DS)-type procedures in patients with obesity. In addition, to help guide metabolic procedure selection for those patients categorized as having severe T2D. This is a retrospective single cohort study of all patients with T2D and severe obesity, who underwent DS-type procedures at a single institution from December 2010 to December 2018. Study endpoints included validating the IMS score in our cohort and evaluating the impact of DS-type procedures on long-term (≥ 5 years) remission of T2D, especially in patients with severe disease. A receiver operator characteristic curve was used to assess the accuracy of the IMS score using the area under the curve (AUC). The study cohort included 30 patients with complete baseline and long-term glycaemic data after their index DS-type surgery. Twelve patients (40%) were classified with severe T2D, and the distribution of IMS-based severity groups was similar between our cohort and the original IMS study (P = .42). IMS scores predicted long-term T2D remission with AUC = 0.77. Patients with IMS-based severe diabetes achieved significantly higher long-term remission after DS-type procedures compared with gastric bypass and/or sleeve gastrectomy from the original IMS study (42% vs. 12%; P < .05). The IMS score properly classifies the severity of T2D in our study cohort and adequately predicts its long-term remission after DS-type procedures. While T2D remission decreases with more severe IMS scores, long-term remission remains high after DS-type procedures among patients with severe disease.

Identifiants

pubmed: 38725101
doi: 10.1111/dom.15647
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024 The Authors. Diabetes, Obesity and Metabolism published by John Wiley & Sons Ltd.

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Auteurs

Sultan Almuallem (S)

Center for Bariatric Surgery, Department of Surgery, McGill University, Montreal, Canada.

Abdulaziz Karam Ali (AK)

Center for Bariatric Surgery, Department of Surgery, McGill University, Montreal, Canada.

Phil Vourtzoumis (P)

Center for Bariatric Surgery, Department of Surgery, McGill University, Montreal, Canada.

Sebastian Demyttenaere (S)

Center for Bariatric Surgery, Department of Surgery, McGill University, Montreal, Canada.

Olivier Court (O)

Center for Bariatric Surgery, Department of Surgery, McGill University, Montreal, Canada.

Amin Andalib (A)

Center for Bariatric Surgery, Department of Surgery, McGill University, Montreal, Canada.

Classifications MeSH