Post-COVID-19 patients in geriatric rehabilitation substantially recover in daily functioning and quality of life.
COVID-19
geriatric rehabilitation
older people
recovery
Journal
Age and ageing
ISSN: 1468-2834
Titre abrégé: Age Ageing
Pays: England
ID NLM: 0375655
Informations de publication
Date de publication:
01 May 2024
01 May 2024
Historique:
received:
08
11
2023
medline:
10
5
2024
pubmed:
10
5
2024
entrez:
10
5
2024
Statut:
ppublish
Résumé
After an acute infection, older persons may benefit from geriatric rehabilitation (GR). This study describes the recovery trajectories of post-COVID-19 patients undergoing GR and explores whether frailty is associated with recovery. Multicentre prospective cohort study. 59 GR facilities in 10 European countries. Post-COVID-19 patients admitted to GR between October 2020 and October 2021. Patients' characteristics, daily functioning (Barthel index; BI), quality of life (QoL; EQ-5D-5L) and frailty (Clinical Frailty Scale; CFS) were collected at admission, discharge, 6 weeks and 6 months after discharge. We used linear mixed models to examine the trajectories of daily functioning and QoL. 723 participants were included with a mean age of 75 (SD: 9.91) years. Most participants were pre-frail to frail (median [interquartile range] CFS 6.0 [5.0-7.0]) at admission. After admission, the BI first steeply increased from 11.31 with 2.51 (SE 0.15, P < 0.001) points per month and stabilised around 17.0 (quadratic slope: -0.26, SE 0.02, P < 0.001). Similarly, EQ-5D-5L first steeply increased from 0.569 with 0.126 points per month (SE 0.008, P < 0.001) and stabilised around 0.8 (quadratic slope: -0.014, SE 0.001, P < 0.001). Functional recovery rates were independent of frailty level at admission. QoL was lower at admission for frailer participants, but increased faster, stabilising at almost equal QoL values for frail, pre-frail and fit patients. Post-COVID-19 patients admitted to GR showed substantial recovery in daily functioning and QoL. Frailty at GR admission was not associated with recovery and should not be a reason to exclude patients from GR.
Sections du résumé
BACKGROUND
BACKGROUND
After an acute infection, older persons may benefit from geriatric rehabilitation (GR).
OBJECTIVES
OBJECTIVE
This study describes the recovery trajectories of post-COVID-19 patients undergoing GR and explores whether frailty is associated with recovery.
DESIGN
METHODS
Multicentre prospective cohort study.
SETTING
METHODS
59 GR facilities in 10 European countries.
PARTICIPANTS
METHODS
Post-COVID-19 patients admitted to GR between October 2020 and October 2021.
METHODS
METHODS
Patients' characteristics, daily functioning (Barthel index; BI), quality of life (QoL; EQ-5D-5L) and frailty (Clinical Frailty Scale; CFS) were collected at admission, discharge, 6 weeks and 6 months after discharge. We used linear mixed models to examine the trajectories of daily functioning and QoL.
RESULTS
RESULTS
723 participants were included with a mean age of 75 (SD: 9.91) years. Most participants were pre-frail to frail (median [interquartile range] CFS 6.0 [5.0-7.0]) at admission. After admission, the BI first steeply increased from 11.31 with 2.51 (SE 0.15, P < 0.001) points per month and stabilised around 17.0 (quadratic slope: -0.26, SE 0.02, P < 0.001). Similarly, EQ-5D-5L first steeply increased from 0.569 with 0.126 points per month (SE 0.008, P < 0.001) and stabilised around 0.8 (quadratic slope: -0.014, SE 0.001, P < 0.001). Functional recovery rates were independent of frailty level at admission. QoL was lower at admission for frailer participants, but increased faster, stabilising at almost equal QoL values for frail, pre-frail and fit patients.
CONCLUSIONS
CONCLUSIONS
Post-COVID-19 patients admitted to GR showed substantial recovery in daily functioning and QoL. Frailty at GR admission was not associated with recovery and should not be a reason to exclude patients from GR.
Identifiants
pubmed: 38725361
pii: 7667811
doi: 10.1093/ageing/afae084
pii:
doi:
Types de publication
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Leiden University Fund
ID : LEF2106-2-47
Organisme : Zorg Onderzoek Nederland en Medische Wetenschappen
ID : 10430102110005
Organisme : University Network of the Care sector South-Holland
ID : 640001003
Organisme : UK National Institute of Health Research Academic Research Collaboration-East Midlands
Investigateurs
Eva Topinková
(E)
Lucie Bautzká
(L)
Helena Michaálková
(H)
Stefan Grund
(S)
Thomas Mross
(T)
Lotte Feesche
(L)
Rebekka Leonhardt
(R)
Clemens Becker
(C)
Jan Gerhardus
(J)
Brigitte R Metz
(BR)
Diana Franke-Chowdhury
(D)
Rose Galvin
(R)
Aoife McCarthy
(A)
Frances Dockery
(F)
Kara McLoughlin
(K)
Bahaa Francis
(B)
Matteo Cesari
(M)
Annalisa Valentini
(A)
Mark Vassallo
(M)
Maria Bonnici
(M)
Olga Nikolaevna Tkacheva
(ON)
Ksenia Eruslanova
(K)
Luba Matchekhina
(L)
Laura Monica Perez Bazan
(LM)
Esther Roquer Fanlo
(ER)
Anna Renom Guiteras
(AR)
Lizzeth Angela Canchucaja
(LA)
Beatriz Pallardo
(B)
Sergio Martínez Zujeros
(SM)
Margarita Viñuela
(M)
Oriol Miralles Resina
(O)
Gema Isabel Dominguez
(GI)
Sarah Caro Bragado
(SC)
Nadia Stasi
(N)
Jennifer Garrillo Cepeda
(JG)
Marta Arroyo-Huidobro
(M)
Ana Gonzalez
(A)
Wilco Achterberg
(W)
Monique Caljouw
(M)
Miriam Haaksma
(M)
Lisa van Tol
(L)
Saskia Drijver
(S)
Paula Vonk
(P)
Liesbeth Sikken
(L)
Irma Baars
(I)
Nathalie Deden
(N)
Gerda Nijgh
(G)
Sylvia van der Drift
(S)
Heike de Wever
(H)
Els Calle
(E)
Kaoutar Karramass
(K)
Josette Hendriks
(J)
Lauren Ebbes
(L)
Anne Hartman
(A)
Hatice Koc
(H)
Laura de Vries
(L)
Hylco Bouwstra
(H)
Laura Langendoen-Wigman
(L)
Berber Oldenbeuving
(B)
Sabine Noordam-Hemeltjen
(S)
Liesbeth Lanting
(L)
Lulu Andela
(L)
Mathilde Meerkerk
(M)
Lianne Willemstein
(L)
Krisztina Krasznai
(K)
Janneke Wolting
(J)
Janette Tazmi
(J)
Eveline Keustermans
(E)
Janetta de Vries
(J)
Sanne van Weers
(S)
Lenni Boogaard
(L)
Simone Been
(S)
Danielle Termeer
(D)
Patricia Te Pas
(P)
Eva Lodewijks
(E)
Jeroen van den Berg
(J)
Sandra Prent
(S)
Marloes Boontje
(M)
Joël Harms
(J)
Jeffrey Bakker
(J)
Carolien de Croon
(C)
Christa van Schieveen
(C)
Ewout Smit
(E)
Patricia van Berlo
(P)
Dionne Ruchtie
(D)
Jane Manson
(J)
Maria Espasandin
(M)
Lucy Abbott
(L)
Sarah Chadwick
(S)
Rebecca Watts
(R)
Melani Dani
(M)
Jackie McNicholas
(J)
Adam Gordon
(A)
Vincent Chau
(V)
Informations de copyright
© The Author(s) 2024. Published by Oxford University Press on behalf of the British Geriatrics Society.