Predicting short- to medium-term care home admission risk in older adults: a systematic review of externally validated models.


Journal

Age and ageing
ISSN: 1468-2834
Titre abrégé: Age Ageing
Pays: England
ID NLM: 0375655

Informations de publication

Date de publication:
01 May 2024
Historique:
received: 19 09 2023
revised: 15 03 2024
medline: 10 5 2024
pubmed: 10 5 2024
entrez: 10 5 2024
Statut: ppublish

Résumé

Predicting risk of care home admission could identify older adults for early intervention to support independent living but require external validation in a different dataset before clinical use. We systematically reviewed external validations of care home admission risk prediction models in older adults. We searched Medline, Embase and Cochrane Library until 14 August 2023 for external validations of prediction models for care home admission risk in adults aged ≥65 years with up to 3 years of follow-up. We extracted and narratively synthesised data on study design, model characteristics, and model discrimination and calibration (accuracy of predictions). We assessed risk of bias and applicability using Prediction model Risk Of Bias Assessment Tool. Five studies reporting validations of nine unique models were included. Model applicability was fair but risk of bias was mostly high due to not reporting model calibration. Morbidities were used as predictors in four models, most commonly neurological or psychiatric diseases. Physical function was also included in four models. For 1-year prediction, three of the six models had acceptable discrimination (area under the receiver operating characteristic curve (AUC)/c statistic 0.70-0.79) and the remaining three had poor discrimination (AUC < 0.70). No model accounted for competing mortality risk. The only study examining model calibration (but ignoring competing mortality) concluded that it was excellent. The reporting of models was incomplete. Model discrimination was at best acceptable, and calibration was rarely examined (and ignored competing mortality risk when examined). There is a need to derive better models that account for competing mortality risk and report calibration as well as discrimination.

Identifiants

pubmed: 38727580
pii: 7668006
doi: 10.1093/ageing/afae088
pii:
doi:

Types de publication

Journal Article Systematic Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Legal and General PLC
Organisme : Advanced Care Research Centre at the University of Edinburgh
Organisme : National Institute for Health Research (NIHR) Artificial Intelligence and Multimorbidity: Clustering in Individuals, Space and Clinical Context
ID : NIHR202639

Informations de copyright

© The Author(s) 2024. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Auteurs

Leonard Ho (L)

Advanced Care Research Centre, Usher Institute, University of Edinburgh, Edinburgh, UK.

Carys Pugh (C)

Advanced Care Research Centre, Usher Institute, University of Edinburgh, Edinburgh, UK.

Sohan Seth (S)

Advanced Care Research Centre, Usher Institute, University of Edinburgh, Edinburgh, UK.

Stella Arakelyan (S)

Advanced Care Research Centre, Usher Institute, University of Edinburgh, Edinburgh, UK.

Nazir I Lone (NI)

Royal Infirmary of Edinburgh, NHS Lothian, Edinburgh, UK.
Centre for Population Health Sciences, Usher Institute, University of Edinburgh, Edinburgh, UK.

Marcus J Lyall (MJ)

Royal Infirmary of Edinburgh, NHS Lothian, Edinburgh, UK.

Atul Anand (A)

Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.

Jacques D Fleuriot (JD)

Advanced Care Research Centre, Usher Institute, University of Edinburgh, Edinburgh, UK.
School of Informatics, University of Edinburgh, Edinburgh, UK.

Paola Galdi (P)

School of Informatics, University of Edinburgh, Edinburgh, UK.

Bruce Guthrie (B)

Advanced Care Research Centre, Usher Institute, University of Edinburgh, Edinburgh, UK.

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Classifications MeSH