The Contribution of Vessel Wall Magnetic Resonance Imaging to the Diagnosis of Primary and Secondary Central Nervous System Vasculitis.

MRI VWI cerebral vasculitis magnetic resonance vessel wall

Journal

Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402

Informations de publication

Date de publication:
29 Apr 2024
Historique:
received: 21 12 2023
revised: 11 04 2024
accepted: 24 04 2024
medline: 11 5 2024
pubmed: 11 5 2024
entrez: 11 5 2024
Statut: epublish

Résumé

To describe high-resolution brain vessel wall MRI (VW-MRI) patterns and morphological brain findings in central nervous system (CNS) vasculitis patients. Fourteen patients with confirmed CNS Vasculitis from two tertiary centers underwent VW-MRI using a 3T scanner. The images were reviewed by two neuroradiologists to assess vessel wall enhancement characteristics and locations. Fourteen patients were included (six females; average age 48 ± 19 years). Diagnoses included primary CNS vasculitis (PCNSV) in six patients and secondary CNS vasculitis (SCNSV) in eight, half of which were infection-related. Thirteen patients showed vessel wall enhancement, which was intense in eleven patients (84.6%) and concentric in twelve (92.3%), affecting the anterior circulation in nine patients (69.2%), posterior in two patients (15.4%), and both circulations in two patients (15.4%). The enhancement patterns were similar across different CNS vasculitis types. DWI changes corresponded with areas of vessel wall enhancement in 77% of patients. Conclusions

Sections du résumé

BACKGROUND BACKGROUND
To describe high-resolution brain vessel wall MRI (VW-MRI) patterns and morphological brain findings in central nervous system (CNS) vasculitis patients.
METHODS METHODS
Fourteen patients with confirmed CNS Vasculitis from two tertiary centers underwent VW-MRI using a 3T scanner. The images were reviewed by two neuroradiologists to assess vessel wall enhancement characteristics and locations.
RESULTS RESULTS
Fourteen patients were included (six females; average age 48 ± 19 years). Diagnoses included primary CNS vasculitis (PCNSV) in six patients and secondary CNS vasculitis (SCNSV) in eight, half of which were infection-related. Thirteen patients showed vessel wall enhancement, which was intense in eleven patients (84.6%) and concentric in twelve (92.3%), affecting the anterior circulation in nine patients (69.2%), posterior in two patients (15.4%), and both circulations in two patients (15.4%). The enhancement patterns were similar across different CNS vasculitis types. DWI changes corresponded with areas of vessel wall enhancement in 77% of patients. Conclusions

Identifiants

pubmed: 38732340
pii: diagnostics14090927
doi: 10.3390/diagnostics14090927
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Associazione Italiana Neuroradiologia (AINR)
ID : Prize Young Topic 2023 Neuroradiologia Diagnostica

Auteurs

Serena D'Aniello (S)

Department of Advanced Biomedical Science, University of Napoli "Federico II", 80125 Naples, Italy.

Arianna Rustici (A)

Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, 40138 Bologna, Italy.
Neuroradiology Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, Ospedale Maggiore, 40133 Bologna, Italy.

Laura Ludovica Gramegna (LL)

Vall d'Hebron Research Institute, Vall d'Hebron Barcelona Hospital Campus, 08035 Barcelona, Spain.
Servicio de Radiología, Unidad de Neuroradiología, Hospital del Mar, 08003 Barcelona, Spain.

Claudia Godi (C)

Neuroradiology Unit and CERMAC, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Neuroradiology Unit, Sant'Antonio Abate Hospital, ASST Valle Olona, 21013 Gallarate, Italy.

Laura Piccolo (L)

Neurology and Stroke Center, IRCCS Istituto delle Scienze Neurologiche di Bologna, Ospedale Maggiore, 40133 Bologna, Italy.

Mauro Gentile (M)

Neurology and Stroke Center, IRCCS Istituto delle Scienze Neurologiche di Bologna, Ospedale Maggiore, 40133 Bologna, Italy.

Andrea Zini (A)

Neurology and Stroke Center, IRCCS Istituto delle Scienze Neurologiche di Bologna, Ospedale Maggiore, 40133 Bologna, Italy.

Alessandro Carrozzi (A)

Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40138 Bologna, Italy.

Raffaele Lodi (R)

Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, 40138 Bologna, Italy.
Functional and Molecular Neuroimaging Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, 40123 Bologna, Italy.

Caterina Tonon (C)

Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, 40138 Bologna, Italy.
Functional and Molecular Neuroimaging Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, 40123 Bologna, Italy.

Massimo Dall'Olio (M)

Neuroradiology Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, Ospedale Bellaria, 40139 Bologna, Italy.

Luigi Simonetti (L)

Neuroradiology Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, Ospedale Maggiore, 40133 Bologna, Italy.

Raffaella Chieffo (R)

Experimental Neurophysiology Unit, IRCCS San Raffaele, Institute of Experimental Neurology (INSPE), 20132 Milan, Italy.

Nicoletta Anzalone (N)

Neuroradiology Unit and CERMAC, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.

Luigi Cirillo (L)

Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, 40138 Bologna, Italy.
Functional and Molecular Neuroimaging Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, 40123 Bologna, Italy.
Neuroradiology Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, Ospedale Bellaria, 40139 Bologna, Italy.

Classifications MeSH