The Effect of Phenolic-Rich Extracts of

Humans Caco-2 Cells Plant Extracts / pharmacology Rubus / chemistry Morus / chemistry Phenols / pharmacology Oxidative Stress / drug effects Antioxidants / pharmacology Cell Proliferation / drug effects Fruit / chemistry Antineoplastic Agents, Phytogenic / pharmacology Chromatography, High Pressure Liquid
antioxidant potential antiproliferative activities blackberries mulberries phenolics

Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
30 Apr 2024
Historique:
received: 14 04 2024
revised: 25 04 2024
accepted: 28 04 2024
medline: 11 5 2024
pubmed: 11 5 2024
entrez: 11 5 2024
Statut: epublish

Résumé

Currently, a clear interest has been given to berries due to their richness in active metabolites, including anthocyanins and non-coloured phenolics. Therefore, the main aim of the present work is to investigate the phenolic profile, antioxidant abilities, and antiproliferative effects on normal human dermal fibroblasts (NHDF) and human colon carcinoma cell line (Caco-2) cells of phenolic-rich extracts from three red fruits highly appreciated by consumers: two species of blackberries (

Identifiants

DOI: 10.3390/nu16091361 PMID: 38732606
pubmed: 38732606
pii: nu16091361
doi: 10.3390/nu16091361
pii:
doi:

Substances chimiques

Plant Extracts 0
Phenols 0
Antioxidants 0
Antineoplastic Agents, Phytogenic 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Fundação para a Ciência e Tecnologia
ID : 2020.04947.BD

Auteurs

Mariana S Martins (MS)

CICS-UBI-Health Sciences Research Centre, University of Beira Interior, 6201-001 Covilhã, Portugal.

Márcio Rodrigues (M)

CICS-UBI-Health Sciences Research Centre, University of Beira Interior, 6201-001 Covilhã, Portugal.
Research Unit for Inland Development, Polytechnic Institute of Guarda (UDI-IPG), 6300-654 Guarda, Portugal.
ORCID: 0000-0002-7010-0619

José David Flores-Félix (JD)

CICS-UBI-Health Sciences Research Centre, University of Beira Interior, 6201-001 Covilhã, Portugal.
Microbiology and Genetics Department, University of Salamanca, 37007 Salamanca, Spain.
ORCID: 0000-0003-2200-4400

Cristina Garcia-Viguera (C)

Laboratorio de Fitoquímica y Alimentos Saludables (LabFAS), Department Food Science and Technology, CSIC, CEBAS, Campus Universitario 25, Espinardo, 30100 Murcia, Spain.
ORCID: 0000-0002-4751-3917

Diego A Moreno (DA)

Laboratorio de Fitoquímica y Alimentos Saludables (LabFAS), Department Food Science and Technology, CSIC, CEBAS, Campus Universitario 25, Espinardo, 30100 Murcia, Spain.
ORCID: 0000-0002-6547-8764

Gilberto Alves (G)

CICS-UBI-Health Sciences Research Centre, University of Beira Interior, 6201-001 Covilhã, Portugal.
ORCID: 0000-0002-4213-0714

Luís R Silva (LR)

CICS-UBI-Health Sciences Research Centre, University of Beira Interior, 6201-001 Covilhã, Portugal.
SPRINT-Sport Physical Activity and Health Research & Innovation Center, Instituto Politécnico da Guarda, 6300-559 Guarda, Portugal.
CERES, Department of Chemical Engineering, University of Coimbra, 3030-790 Coimbra, Portugal.
ORCID: 0000-0001-5264-3516

Ana C Gonçalves (AC)

CICS-UBI-Health Sciences Research Centre, University of Beira Interior, 6201-001 Covilhã, Portugal.
CIBIT-Coimbra Institute for Biomedical Imaging and Translational Research, University of Coimbra, 3000-548 Coimbra, Portugal.
ORCID: 0000-0001-7795-795X

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › The Effect of Phenolic-Rich Extracts of
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules Caco-2 › The Effect of Phenolic-Rich Extracts of
questionsmedicales.fr › Préparations pharmaceutiques › Extraits de plantes › The Effect of Phenolic-Rich Extracts of
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Rosanae › Rosales › Rosaceae › Rubus › The Effect of Phenolic-Rich Extracts of
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Rosanae › Rosales › Moraceae › Morus › The Effect of Phenolic-Rich Extracts of
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures aromatiques › Dérivés du benzène › Phénols › The Effect of Phenolic-Rich Extracts of
questionsmedicales.fr › Phénomènes physiologiques › Stress physiologique › Stress oxydatif › The Effect of Phenolic-Rich Extracts of
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Agents protecteurs › Antioxydants › The Effect of Phenolic-Rich Extracts of
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Croissance › Processus de croissance cellulaire › Prolifération cellulaire › The Effect of Phenolic-Rich Extracts of
questionsmedicales.fr › Aliments et boissons › Aliments › Fruit › The Effect of Phenolic-Rich Extracts of
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antinéoplasiques › Antinéoplasiques d'origine végétale › The Effect of Phenolic-Rich Extracts of
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Chromatographie › Chromatographie en phase liquide › Chromatographie en phase liquide à haute performance › The Effect of Phenolic-Rich Extracts of