Impact of artificial accelerated ageing of PVC surfaces and surface degradation on disinfectant efficacy.
Biocidal formulation
PVC
accelerated surface ageing
surface disinfection
Journal
The Journal of hospital infection
ISSN: 1532-2939
Titre abrégé: J Hosp Infect
Pays: England
ID NLM: 8007166
Informations de publication
Date de publication:
09 May 2024
09 May 2024
Historique:
received:
03
10
2023
revised:
06
12
2023
accepted:
17
12
2023
medline:
12
5
2024
pubmed:
12
5
2024
entrez:
11
5
2024
Statut:
aheadofprint
Résumé
Standardised efficacy surface tests for disinfectants are performed on pristine surfaces. There is a growing interest in understanding the impact of surface ageing on disinfectant activity, owing for example to the increased usage of UV radiation and oxidative chemistries for surface decontamination. This acknowledges that general surface "wear and tear" following UV radiation and oxidative biocide exposure may impact biocidal product efficacy. PVC surfaces were aged through thermal and UV-A radiation (340nm wavelength) following the use of standard ageing surface protocols to simulate natural surface degradation. Surface roughness, contact angle and scanning electron microscopy were performed to evaluate physical changes in PVC surfaces before and after artificial ageing. The efficacy of five pre-impregnated disinfectant wipes were evaluated using the ASTM E2967-15 on stainless steel (control) and PVC surfaces (aged and non-aged). The type of formulation and the organism tested remained the most significant factors impacting disinfectant efficacy, compared to surface type. Both thermal ageing and UV-A exposure of PVC surfaces, clearly showed signs of surface degradation, notably an increase in surface roughness. Physical changes were observed in the roughness of PVC after artificial ageing. A difference in disinfectant efficacy dependent on aged PVC surfaces was observed for some, but not all formulations. We showed that surface type and surface ageing can affect biocidal product efficacy, although in a non-predictable manner. More research is needed in this field to ascertain whether surface types and aged surfaces should be used in standardized efficacy testing.
Sections du résumé
BACKGROUND
BACKGROUND
Standardised efficacy surface tests for disinfectants are performed on pristine surfaces. There is a growing interest in understanding the impact of surface ageing on disinfectant activity, owing for example to the increased usage of UV radiation and oxidative chemistries for surface decontamination. This acknowledges that general surface "wear and tear" following UV radiation and oxidative biocide exposure may impact biocidal product efficacy.
METHODS
METHODS
PVC surfaces were aged through thermal and UV-A radiation (340nm wavelength) following the use of standard ageing surface protocols to simulate natural surface degradation. Surface roughness, contact angle and scanning electron microscopy were performed to evaluate physical changes in PVC surfaces before and after artificial ageing. The efficacy of five pre-impregnated disinfectant wipes were evaluated using the ASTM E2967-15 on stainless steel (control) and PVC surfaces (aged and non-aged).
RESULTS
RESULTS
The type of formulation and the organism tested remained the most significant factors impacting disinfectant efficacy, compared to surface type. Both thermal ageing and UV-A exposure of PVC surfaces, clearly showed signs of surface degradation, notably an increase in surface roughness. Physical changes were observed in the roughness of PVC after artificial ageing. A difference in disinfectant efficacy dependent on aged PVC surfaces was observed for some, but not all formulations.
CONCLUSION
CONCLUSIONS
We showed that surface type and surface ageing can affect biocidal product efficacy, although in a non-predictable manner. More research is needed in this field to ascertain whether surface types and aged surfaces should be used in standardized efficacy testing.
Identifiants
pubmed: 38734184
pii: S0195-6701(24)00158-0
doi: 10.1016/j.jhin.2023.12.021
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest Claire Khosravi, Peter Teska, Gary Bradburne are Diverey employees.