Bilateral bartholin's gland abscesses in a 4-year-old girl with vitamin a deficiency: a case report.
Prevotella bivia
Streptococcus constellatus
Bartholin’s gland abscesses
Case report
Infant
Journal
BMC infectious diseases
ISSN: 1471-2334
Titre abrégé: BMC Infect Dis
Pays: England
ID NLM: 100968551
Informations de publication
Date de publication:
11 May 2024
11 May 2024
Historique:
received:
05
01
2024
accepted:
06
05
2024
medline:
12
5
2024
pubmed:
12
5
2024
entrez:
11
5
2024
Statut:
epublish
Résumé
A Bartholin's gland abscess is one of the most common infections in women of reproductive age. Although Bartholin's gland abscesses have been reported in prepubertal children, they are rarer in prepubertal children than in adults. Herein, we report a case of bilateral Bartholin's gland abscesses in a 4-year-old girl with vitamin A deficiency. A 4-year-old girl diagnosed with autism spectrum disorder was admitted to the hospital for close examination and treatment because of persistent fever and malaise. The child was a marked fussy eater and was diagnosed with corneal ulceration and night blindness secondary to vitamin A deficiency. Both of the patient's labia were swollen, and a diagnosis of a bilateral Bartholin's gland abscess was made using computed tomography. Incisional drainage was performed under general anesthesia. The patient's postoperative course was uneventful, and she was discharged from the hospital on day 8 after the surgery. During hospitalization, attempts were made to correct the vitamin deficiency by adding nutritional supplements to the diet. Three months after the surgery, no recurrence of abscesses was noted. Decreased immunocompetence and mucosal barrier function due to vitamin A deficiency is thought to be the underlying cause of Bartholin's gland abscesses. Although prepubertal Bartholin's gland abscesses have been reported, they are rare. To the best of our knowledge, no reports of bilateral Bartholin's gland abscesses potentially caused by vitamin A deficiency have been reported. When prepubertal girls present with Bartholin's gland abscesses, the presence of immunodeficiency due to vitamin or trace element deficiency should also be considered.
Sections du résumé
BACKGROUND
BACKGROUND
A Bartholin's gland abscess is one of the most common infections in women of reproductive age. Although Bartholin's gland abscesses have been reported in prepubertal children, they are rarer in prepubertal children than in adults. Herein, we report a case of bilateral Bartholin's gland abscesses in a 4-year-old girl with vitamin A deficiency.
CASE PRESENTATION
METHODS
A 4-year-old girl diagnosed with autism spectrum disorder was admitted to the hospital for close examination and treatment because of persistent fever and malaise. The child was a marked fussy eater and was diagnosed with corneal ulceration and night blindness secondary to vitamin A deficiency. Both of the patient's labia were swollen, and a diagnosis of a bilateral Bartholin's gland abscess was made using computed tomography. Incisional drainage was performed under general anesthesia. The patient's postoperative course was uneventful, and she was discharged from the hospital on day 8 after the surgery. During hospitalization, attempts were made to correct the vitamin deficiency by adding nutritional supplements to the diet. Three months after the surgery, no recurrence of abscesses was noted.
CONCLUSIONS
CONCLUSIONS
Decreased immunocompetence and mucosal barrier function due to vitamin A deficiency is thought to be the underlying cause of Bartholin's gland abscesses. Although prepubertal Bartholin's gland abscesses have been reported, they are rare. To the best of our knowledge, no reports of bilateral Bartholin's gland abscesses potentially caused by vitamin A deficiency have been reported. When prepubertal girls present with Bartholin's gland abscesses, the presence of immunodeficiency due to vitamin or trace element deficiency should also be considered.
Identifiants
pubmed: 38734601
doi: 10.1186/s12879-024-09382-1
pii: 10.1186/s12879-024-09382-1
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
487Informations de copyright
© 2024. The Author(s).
Références
Singh JK, Viruthagiri A, Sadasivan J. Bartholin’s gland abscess–a rarity in infants and children. Curr Pediatr Res. 2010;14:63–4.
Radhakrishna V, Goel R, Parashar G, Santhanakrishnan R. Bartholin’s gland abscess in a prepubertal female: a case report. Ann Med Surg (Lond). 2017;24:1–2.
doi: 10.1016/j.amsu.2017.09.017
pubmed: 29062477
El Kady S, Al Zahrani A, Jednak R, El Sherbiny M. Bartholin’s gland abscess in a neonate: a case report. Can Urol Assoc J. 2007;1:117–9.
pubmed: 18542776
pmcid: 2422937
Title of subordinate document. In: Title of main document. Publisher. Year of publication. https://www.mhlw.go.jp/file/05-Shingikai-10901000-Kenkoukyoku-Soumuka/0000042635.pdf . (Author name(s), Japanese.). Accessed 13 Mar 2024.
Amimo JO, Michael H, Chepngeno J, Raev SA, Saif LJ, Vlasova AN. Immune impairment associated with vitamin a deficiency: insights from clinical studies and animal model research. Nutrients. 2022;14:5038.
doi: 10.3390/nu14235038
pubmed: 36501067
pmcid: 9738822
Abdelkader A, Wahba AA, El-Tonsy M, Zewail AA, Shams Eldin M. Recurrent respiratory infections and vitamin A levels: a link? It is cross-sectional. Med (Baltim). 2022;101:e30108.
doi: 10.1097/MD.0000000000030108
Cevik M, Savas M, Guldur ME, Boleken ME. Urinary retention as the presentation of Bartholin’s duct cyst in a neonate. J Pediatr Adolesc Gynecol. 2012;25:e65–7.
doi: 10.1016/j.jpag.2011.12.071
pubmed: 22578485
Chavarría JF, Faingezicht I. Bartholin’s gland abscess in a neonate. Pediatr Infect Dis J. 1989;8:334–5.
pubmed: 2657620
Revathi N, Pandey A, Patra V, Seth B. Bilateral vulvar abscess in an infant–an unusual occurrence. New Indian J Pediatr. 2017;6:244–6.
doi: 10.4103/2667-3592.301362
Popovic N, Zvizdic Z, Milisic E, Jonuzi A, Karamustafic A. Large Bartholin’s gland cyst in a premenarchal girl: a rare clinical finding. Iran J Pediatr Surg. 2018;4:105–8.
Mayo-Wilson E, Imdad A, Herzer K, Yakoob MY, Bhutta ZA. Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis. BMJ. 2011;343:d5094.
doi: 10.1136/bmj.d5094
pubmed: 21868478
pmcid: 3162042
Schauffler GC, Kanzler R, Schauffler C. Management of 256 cases of infection of the immature vagina. JAMA. 1939;112:411–7.
doi: 10.1001/jama.1939.02800050025006
Kubitz R, Hoffman K. Bartholin’s gland abscess in an infant. A case report. J Reprod Med. 1986;31:67–9.
pubmed: 3950888
Ernst EA, Weller P, Karch SB. Bartholin’s gland abscess in infancy. Pediatr Infect Dis J. 1988;7:526–7.
doi: 10.1097/00006454-198807000-00023
pubmed: 3043366
Lamontagne F, Masse M-H, Menard J, Sprague S, Pinto R, Heyland DK, et al. Intravenous vitamin C in adults with sepsis in the intensive care unit. N Engl J Med. 2022;386:2387–98.
doi: 10.1056/NEJMoa2200644
pubmed: 35704292