Acute Aseptic Meningitis Temporally Associated with Intravenous Polyclonal Immunoglobulin Therapy: A Systematic Review.
Aseptic meningitis
Autoimmune disorder
Drug-induced meningitis
Intravenous polyclonal human immunoglobulin
Meta-analysis
Systematic review
Journal
Clinical reviews in allergy & immunology
ISSN: 1559-0267
Titre abrégé: Clin Rev Allergy Immunol
Pays: United States
ID NLM: 9504368
Informations de publication
Date de publication:
13 May 2024
13 May 2024
Historique:
accepted:
16
03
2024
medline:
13
5
2024
pubmed:
13
5
2024
entrez:
13
5
2024
Statut:
aheadofprint
Résumé
An acute aseptic meningitis has been occasionally observed on intravenous polyclonal human immunoglobulin therapy. Since case reports cannot be employed to draw inferences about the relationships between immunoglobulin therapy and meningitis, we conducted a systematic review and meta-analysis of the literature. Eligible were cases, case series, and pharmacovigilance studies. We found 71 individually documented cases (36 individuals ≤ 18 years of age) of meningitis. Ninety percent of cases presented ≤ 3 days after initiating immunoglobulin therapy and recovered within ≤ 7 days (with a shorter disease duration in children: ≤ 3 days in 29 (94%) cases). In 22 (31%) instances, the authors noted a link between the onset of meningitis and a rapid intravenous infusion of immunoglobulins. Cerebrospinal fluid analysis revealed a predominantly neutrophilic (N = 46, 66%) pleocytosis. Recurrences after re-exposure were observed in eight (N = 11%) patients. Eight case series addressed the prevalence of meningitis in 4089 patients treated with immunoglobulins. A pooled prevalence of 0.6% was noted. Finally, pharmacovigilance data revealed that meningitis temporally associated with intravenous immunoglobulin therapy occurred with at least five different products. In conclusion, intravenous immunoglobulin may cause an acute aseptic meningitis. The clinical features remit rapidly after discontinuing the medication.
Identifiants
pubmed: 38739354
doi: 10.1007/s12016-024-08989-1
pii: 10.1007/s12016-024-08989-1
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024. The Author(s).
Références
Hasbun R (2000) The acute aseptic meningitis syndrome. Curr Infect Dis Rep 2:345–351. https://doi.org/10.1007/s11908-000-0014-z
doi: 10.1007/s11908-000-0014-z
pubmed: 11095876
Lee BE, Davies HD (2007) Aseptic meningitis. Curr Opin Infect Dis 20:272–277. https://doi.org/10.1097/QCO.0b013e3280ad4672
doi: 10.1097/QCO.0b013e3280ad4672
pubmed: 17471037
Wallgren A (1924) Une nouvelle maladie infectieuse du système nerveux central? méningite aseptique aiguë. Acta Paediatr 4:158–182. https://doi.org/10.1111/j.1651-2227.1924.tb17242.x
doi: 10.1111/j.1651-2227.1924.tb17242.x
Perez EE, Orange JS, Bonilla F, Chinen J, Chinn IK, Dorsey M, El-Gamal Y, Harville TO, Hossny E, Mazer B, Nelson R, Secord E, Jordan SC, Stiehm ER, Vo AA, Ballow M (2017) Update on the use of immunoglobulin in human disease: a review of evidence. J Allergy Clin Immunol 139:S1–S46. https://doi.org/10.1016/j.jaci.2016.09.023
doi: 10.1016/j.jaci.2016.09.023
pubmed: 28041678
Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, Li T, Loder EW, Mayo-Wilson E, McDonald S, McGuinness LA, Stewart LA, Thomas J, Tricco AC, Welch VA, Whiting P, Moher D (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. J Clin Epidemiol 134:178–189. https://doi.org/10.1016/j.jclinepi.2021.03.001
doi: 10.1016/j.jclinepi.2021.03.001
pubmed: 33789819
Hanly JG, Urowitz MB, Gordon C, Bae SC, Romero-Diaz J, Sanchez-Guerrero J, Bernatsky S, Clarke AE, Wallace DJ, Isenberg DA, Rahman A, Merrill JT, Fortin PR, Gladman DD, Bruce IN, Petri M, Ginzler EM, Dooley MA, Ramsey-Goldman R, Manzi S, Jönsen A, Alarcón GS, van Vollenhoven RF, Aranow C, Mackay M, Ruiz-Irastorza G, Lim S, Inanc M, Kalunian KC, Jacobsen S, Peschken CA, Kamen DL, Askanase A, Farewell V (2020) Neuropsychiatric events in systemic lupus erythematosus: a longitudinal analysis of outcomes in an international inception cohort using a multistate model approach. Ann Rheum Dis 79:356–362. https://doi.org/10.1136/annrheumdis-2019-216150
doi: 10.1136/annrheumdis-2019-216150
pubmed: 31915121
Jolles S, Sewell WA, Leighton C (2000) Drug-induced aseptic meningitis: diagnosis and management. Drug Saf 22:215–226. https://doi.org/10.2165/00002018-200022030-00005
doi: 10.2165/00002018-200022030-00005
pubmed: 10738845
Vismara SA, Lava SAG, Kottanattu L, Simonetti GD, Zgraggen L, Clericetti CM, Bianchetti MG, Milani GP (2020) Lipschütz’s acute vulvar ulcer: a systematic review. Eur J Pediatr 179:1559–1567. https://doi.org/10.1007/s00431-020-03647-y
doi: 10.1007/s00431-020-03647-y
pubmed: 32296983
Papageorgiou G, Grant SW, Takkenberg JJM, Mokhles MM (2018) Statistical primer: how to deal with missing data in scientific research? Interact Cardiovasc Thorac Surg 27:153–158. https://doi.org/10.1093/icvts/ivy102
doi: 10.1093/icvts/ivy102
pubmed: 29757374
Brown GW, Hayden GF (1985) Nonparametric methods Clinical applications Clin Pediatr (Phila) 24:490–498. https://doi.org/10.1177/000992288502400905
doi: 10.1177/000992288502400905
pubmed: 4017399
Moses LE, Emerson JD, Hosseini H (1984) Analyzing data from ordered categories. N Engl J Med 311:442–448. https://doi.org/10.1056/NEJM198408163110705
doi: 10.1056/NEJM198408163110705
pubmed: 6749191
Kato E, Shindo S, Eto Y, Hashimoto N, Yamamoto M, Sakata Y, Hiyoshi Y (1988) Administration of immune globulin associated with aseptic meningitis. JAMA 259:3269–3271. https://doi.org/10.1001/jama.1988.03720220017010
doi: 10.1001/jama.1988.03720220017010
pubmed: 2453686
Casteels-Van Daele M, Wijndaele L, Hanninck K, Gillis P (1990) Intravenous immune globulin and acute aseptic meningitis. N Engl J Med 323:614–615. https://doi.org/10.1056/NEJM199008303230917
doi: 10.1056/NEJM199008303230917
pubmed: 2381452
Watson JD, Gibson J, Joshua DE, Kronenberg H (1991) Aseptic meningitis associated with high dose intravenous immunoglobulin therapy. J Neurol Neurosurg Psychiatry 54:275–276. https://doi.org/10.1136/jnnp.54.3.275
doi: 10.1136/jnnp.54.3.275
pubmed: 2030359
pmcid: 1014401
Kressebuch H, Schaad UB, Hirt A, Bianchetti MG (1992) Cerebrospinal fluid inflammation induced by intravenous immunoglobulins. Pediatr Infect Dis J 11:894–895. https://doi.org/10.1097/00006454-199210000-00020
doi: 10.1097/00006454-199210000-00020
pubmed: 1408496
Molina JM, Coffineau A, Rain JD, Letonturier D, Modaï J (1992) Aseptic meningitis following administration of intravenous immune globulin. Clin Infect Dis 15:564–565. https://doi.org/10.1093/clind/15.3.564
doi: 10.1093/clind/15.3.564
pubmed: 1520817
Mselati JC, Carlier JC, Routon MC, Noui Mehidi F, de Gennes C (1992) Immunoglobulines intraveineuses et méningite aseptique [Intravenous immunoglobulins and aseptic meningitis]. Arch Fr Pédiatr Mar 49:216
Pallares DE, Marshall GS (1992) Acute aseptic meningitis associated with administration of intravenous immune globulin. Am J Pediatr Hematol Oncol 14:279. https://doi.org/10.1097/00043426-199208000-00019
doi: 10.1097/00043426-199208000-00019
pubmed: 1510200
Rao SP, Teitlebaum J, Miller ST (1992) Intravenous immune globulin and aseptic meningitis. Am J Dis Child 146:539–540. https://doi.org/10.1001/archpedi.1992.02160170019004
doi: 10.1001/archpedi.1992.02160170019004
pubmed: 1306046
Vera-Ramirez M, Charlet M, Parry GJ (1992) Recurrent aseptic meningitis complicating intravenous immunoglobulin therapy for chronic inflammatory demyelinating polyradiculoneuropathy. Neurology 42:1636–1637. https://doi.org/10.1212/wnl.42.8.1636-a
doi: 10.1212/wnl.42.8.1636-a
pubmed: 1641167
Meiner Z, Ben-Hur T, River Y, Reches A (1993) Aseptic meningitis as complication of intravenous immunoglobulin therapy for myasthenia gravis. J Neurol Neurosurg Psychiatry 56:830–831. https://doi.org/10.1136/jnnp.56.7.830-a
doi: 10.1136/jnnp.56.7.830-a
pubmed: 8380010
pmcid: 1015071
Mitterer M, Pescosta N, Vogetseder W, Mair M, Coser P (1993) Two episodes of aseptic meningitis during intravenous immunoglobulin therapy of idiopathic thrombocytopenic purpura. Ann Hematol 67:151–152. https://doi.org/10.1007/BF01701743
doi: 10.1007/BF01701743
pubmed: 8373906
De Vlieghere FC, Peetermans WE, Vermylen J (1994) Aseptic granulocytic meningitis following treatment with intravenous immunoglobulin. Clin Infect Dis 18:1008–1010. https://doi.org/10.1093/clinids/18.6.1008
doi: 10.1093/clinids/18.6.1008
pubmed: 8086530
Ellis RJ, Swendson MR, Bajorek J (1994) Aseptic meningitis as a complication of intravenous immunoglobulin therapy for myasthenia gravis. Muscle Nerve 17:683–684. https://doi.org/10.1002/mus.880170620
doi: 10.1002/mus.880170620
pubmed: 8196714
Sekul EA, Cupler EJ, Dalakas MC (1994) Aseptic meningitis associated with high-dose intravenous immunoglobulin therapy: frequency and risk factors. Ann Intern Med 121:259–262. https://doi.org/10.7326/0003-4819-121-4-199408150-00004
doi: 10.7326/0003-4819-121-4-199408150-00004
pubmed: 8037406
FernándezCarril JM, Trejo JM, Sedano MJ, Goñi M (1995) Aseptic meningitis caused by intravenous immunoglobulin. Neurologia 10:351–352
Gabor EP (1995) Intravenous immune globulin. West J Med 162:277–278
pubmed: 7725726
pmcid: 1022730
Oddou S, Molinier S, Coso D, Boulet JM, Gastaut JA, Bouabdallah R (1995) Méningite aseptique consécutive à un traitement par immunoglobulines: intérêt physiopathologique et prognostique de son dépistage [Aseptic meningitis following treatment with immunoglobulins: physiopathological and prognostic value of screening]. Presse Med 24:916
pubmed: 7638138
Preminger-Shapiro R, Nussinovitch M, Soen G, Varsano I (1995) Aseptic meningitis: a frequent side-effect of intravenous immunoglobulin? Eur J Pediatr 154:866–767. https://doi.org/10.1007/BF01959803
doi: 10.1007/BF01959803
pubmed: 8529693
Shorr AF, Kester KE (1996) Meningitis and hepatitis complicating intravenous immunoglobulin therapy. Ann Pharmacother 30:1115–1116. https://doi.org/10.1177/106002809603001010
doi: 10.1177/106002809603001010
pubmed: 8893119
Sirvent N, Monpoux F, Benet L, Mariani R (1996) Méningite aseptique au cours d’un traitement par immunoglobulines [Aseptic meningitis during treatment with immunoglobulins]. Arch Pédiatr 3:830–831. https://doi.org/10.1016/0929-693x(96)82172-5
doi: 10.1016/0929-693x(96)82172-5
pubmed: 8998543
Lafferty TE, DeHoratius RJ, Smith JB (1997) Aseptic meningitis as a side effect of intravenous immune gammaglobulin. J Rheumatol 24:2491–2492
pubmed: 9415672
Picton P, Chisholm M (1997) Aseptic meningitis associated with high dose immunoglobulin: case report. BMJ 315:1203–1204. https://doi.org/10.1136/bmj.315.7117.1203
doi: 10.1136/bmj.315.7117.1203
pubmed: 9393224
pmcid: 2127757
Boyce TG, Spearman P (1998) Acute aseptic meningitis secondary to intravenous immunoglobulin in a patient with Kawasaki syndrome. Pediatr Infect Dis J 17:1054–1056. https://doi.org/10.1097/00006454-199811000-00023
doi: 10.1097/00006454-199811000-00023
pubmed: 9849996
Al-Ghamdi H, Mustafa MM, Al-Fawaz I, Al-Dowaish A (1999) Acute aseptic meningitis associated with administration of immunoglobulin in children: a case report and review of the literature. Ann Saudi Med 19:362–364. https://doi.org/10.5144/0256-4947.1999.362
doi: 10.5144/0256-4947.1999.362
pubmed: 17277543
Piguet C, Fontmarty S, Gilbert B, Vodoff MV, de Lumley L (1999) Purpura thrombopénique idiopathique, immunoglobulines intraveineuses et méningite aseptique [Idiopathic thrombopenic purpura, intravenous immunoglobulins and aseptic meningitis]. Arch Pediatr 6:1350–1351. https://doi.org/10.1016/s0929-693x(00)88905-8
doi: 10.1016/s0929-693x(00)88905-8
pubmed: 10627912
Nelson MA, Carregal VA, DeGuzman RD, Engler RJM (2000) Aseptic meningitis due to intravenous immunoglobulin therapy that resolved with subcutaneous administration. Pediatr Allergy Immunol Pulmonol 14:323–327. https://doi.org/10.1089/088318700750070420
doi: 10.1089/088318700750070420
Obando I, Duran I, Martin-Rosa L, Cano JM, Garcia-Martin FJ (2002) Aseptic meningitis due to administration of intravenous immunoglobulin with an unusually high number of leukocytes in cerebrospinal fluid. Pediatr Emerg Care 18:429–432. https://doi.org/10.1097/00006565-200212000-00006
doi: 10.1097/00006565-200212000-00006
pubmed: 12488836
Wright SE, Shaikh ZH, Castillo-Lugo JA, Tanriover B (2008) Aseptic meningitis and abducens nerve palsy as a serious side effect of high dose intravenous immunoglobulin used in a patient with renal transplantation. Transpl Infect Dis 10:294–297. https://doi.org/10.1111/j.1399-3062.2007.00294.x
doi: 10.1111/j.1399-3062.2007.00294.x
pubmed: 18086279
Asano T, Koizumi S, Mishina-Ikegami K, Hatori T, Miyasho T, Fujino O (2010) Increased levels of monocyte chemoattractant protein-1 in cerebrospinal fluid with gamma globulin induced meningitis. Acta Paediatr 99:164–165. https://doi.org/10.1111/j.1651-2227.2009.01550.x
doi: 10.1111/j.1651-2227.2009.01550.x
pubmed: 19832741
García Norniella B, Morán Poladura M, Fernández Díaz M, Fernández Fernández E, Suárez Castañón C (2011) Meningitis aséptica secundaria a tratamiento con inmunoglobulina intravenosa en la enfermedad de Kawasaki [Aseptic meningitis secondary to intravenous immunoglobulin treatment in Kawasaki disease]. An Pediatr (Barc) 75:79–80. https://doi.org/10.1016/j.anpedi.2010.11.019
doi: 10.1016/j.anpedi.2010.11.019
pubmed: 21420919
Kaarthigeyan K, Burli VV (2011) Aseptic meningitis following intravenous immunoglobulin therapy of common variable immunodeficiency. J Pediatr Neurosci 6:160–161. https://doi.org/10.4103/1817-1745.92858
doi: 10.4103/1817-1745.92858
pubmed: 22408675
pmcid: 3296420
Kemmotsu Y, Nakayama T, Matsuura H, Saji T (2011) Clinical characteristics of aseptic meningitis induced by intravenous immunoglobulin in patients with Kawasaki disease. Pediatr Rheumatol Online J 9:28. https://doi.org/10.1186/1546-0096-9-28
doi: 10.1186/1546-0096-9-28
pubmed: 21917158
pmcid: 3189389
Chaabane A, Hamzaoui A, Aouam K, Klai R, Fredj NB, Boughattas NA, Mahjoub S (2012) Human intravenous immunoglobulin-induced aseptic meningitis: a case report. J Clin Pharmacol 52:279–281. https://doi.org/10.1177/0091270010394183
doi: 10.1177/0091270010394183
pubmed: 21257801
Mullane D, Williams L, Merwick A, Tobin WO, McGuigan C (2012) Drug induced aseptic meningitis caused by intravenous immunoglobulin therapy. Ir Med J 105:182–183
pubmed: 22973657
Ventura F, Rocha J, Fernandes JC, Machado A, Brito C (2013) Recalcitrant pemphigus vulgaris: aseptic meningitis associated with intravenous immunoglobulin therapy and successful treatment with rituximab. Int J Dermatol 52:501–502. https://doi.org/10.1111/j.1365-4632.2010.04870.x
doi: 10.1111/j.1365-4632.2010.04870.x
pubmed: 23451774
Jain RS, Kumar S, Aggarwal R, Kookna JC (2014) Acute aseptic meningitis due to intravenous immunoglobulin therapy in Guillain-Barré syndrome. Oxf Med Case Reports 2014:132–134. https://doi.org/10.1093/omcr/omu051
doi: 10.1093/omcr/omu051
pubmed: 25988056
pmcid: 4370025
Bharath V, Eckert K, Kang M, Chin-Yee IH, Hsia CC (2015) Incidence and natural history of intravenous immunoglobulin-induced aseptic meningitis: a retrospective review at a single tertiary care center. Transfusion 55:2597–2605. https://doi.org/10.1111/trf.13200
doi: 10.1111/trf.13200
pubmed: 26095012
Puy-Nunez A, Dacosta-Balboa M, Cabo-Lopez I, Canneti B, Lopez-Ferreiro A, Rodriguez-Alvarez JR, Rodriguez-Regal A, Mourino-Sestelo MA (2016) Meningitis aseptica como complicaciòn del tratamiento con inmunoglobulinas en la miastenia grave [Aseptic meningitis as a complication of immunoglobulin treatment in myasthenia gravis]. Rev Neurol 62:478–479
pubmed: 27149191
Kumar PA, SubhalaxamiMargekar S (2017) Aseptic meningitis complicating immunoglobulin therapy in AIDP. Pol Ann Med 24:52–54. https://doi.org/10.1016/j.poamed.2016.03.004
doi: 10.1016/j.poamed.2016.03.004
Patel A, Potu KC, Sturm T (2017) A case of IVIG-induced aseptic chemical meningitis. S D Med 70:119–121
pubmed: 28813773
Wanigasekera T, Grainger RJ, Sexton DJ, Magee C (2017) IVIG associated aseptic meningitis in a renal transplant patient. Case Rep Transplant 2017:6962150. https://doi.org/10.1155/2017/6962150
doi: 10.1155/2017/6962150
pubmed: 28620559
pmcid: 5460409
Graça L, Alves J, Nuak J, Sarmento A (2018) Immunoglobulin-induced aseptic meningitis: a case report. BMC Neurol 18:97. https://doi.org/10.1186/s12883-018-1102-8
doi: 10.1186/s12883-018-1102-8
pubmed: 30016937
pmcid: 6048768
Vassalini P, Ajassa C, Di Ruscio V, Morace A, Vergari J, Tosato C, Savelloni G, Mastroianni CM (2019) Aseptic meningitis induced by intravenous immunoglobulins in a child with acute Epstein-Barr virus infection and thrombocytopenia. Infez Med 27:194–197
pubmed: 31205046
Maldonado Slootjes S, Guilmot A, Dubuisson N, van Pesch V, Elsankari S (2020) Intravenous immunoglobulin-induced aseptic meningitis in a patient with Miller Fisher syndrome. Acta Neurol Belg 120:1015–1016. https://doi.org/10.1007/s13760-020-01389-0
doi: 10.1007/s13760-020-01389-0
pubmed: 32449133
Vargas PD, Moreno MA (2021) Meningitis aséptica secundaria a la administración de inmunoglobulina. Rpert Med Cir 30:170–172. https://doi.org/10.31260/RepertMedCir.01217372.899
doi: 10.31260/RepertMedCir.01217372.899
Chan OM, Kuok CI, Chan KYW, Yeung HMR (2022) Immunoglobulin-induced aseptic meningitis in juvenile dermatomyositis: a case report. Cureus 14:e31808. https://doi.org/10.7759/cureus.31808
doi: 10.7759/cureus.31808
pubmed: 36579229
pmcid: 9780508
Russo CC, Dalton LK, Grant L, Enos N, Evans DLA (2022) Patient with severe headache after IV immunoglobulin. Fed Pract 39:487–489. https://doi.org/10.12788/fp.0342
doi: 10.12788/fp.0342
pubmed: 37025981
pmcid: 10071448
Young CC, LaRovere KL, Newhams MM, Kucukak S, Gertz SJ, Maddux AB, Halasa NB, Crandall H, Kong M, Fitzgerald JC, Irby K, Randolph AG, Campbell AP, Son MBF (2023) Overcoming COVID-19 Investigators. Clinical course associated with aseptic meningitis induced by intravenous immunoglobulin for the treatment of multisystem inflammatory syndrome in children. J Pediatr 257:113372. https://doi.org/10.1016/j.jpeds.2023.01.025
doi: 10.1016/j.jpeds.2023.01.025
pubmed: 36870559
Brannagan TH 3rd, Nagle KJ, Lange DJ, Rowland LP (1996) Complications of intravenous immune globulin treatment in neurologic disease. Neurology 47:674–677. https://doi.org/10.1212/wnl.47.3.674
doi: 10.1212/wnl.47.3.674
pubmed: 8797463
Kattamis AC, Shankar S, Cohen AR (1997) Neurologic complications of treatment of childhood acute immune thrombocytopenic purpura with intravenously administered immunoglobulin G. J Pediatr 130:281–283. https://doi.org/10.1016/s0022-3476(97)70355-x
doi: 10.1016/s0022-3476(97)70355-x
pubmed: 9042132
Sherer Y, Levy Y, Langevitz P, Rauova L, Fabrizzi F, Shoenfeld Y (2001) Adverse effects of intravenous immunoglobulin therapy in 56 patients with autoimmune diseases. Pharmacology 62:133–137. https://doi.org/10.1159/000056085
doi: 10.1159/000056085
pubmed: 11287813
Stangel M, Kiefer R, Pette M, Smolka MN, Marx P, Gold R (2003) Side effects of intravenous immunoglobulins in neurological autoimmune disorders - a prospective study. J Neurol 250:818–821. https://doi.org/10.1007/s00415-003-1085-1
doi: 10.1007/s00415-003-1085-1
pubmed: 12883923
Berg R, Fuellenhals E (2016) Aseptic meningitis following therapy with immune globulins: a combination of product features and patient characteristics? Transfusion 56:3021–3028. https://doi.org/10.1111/trf.13886
doi: 10.1111/trf.13886
pubmed: 27807853
Bihan K, Weiss N, Théophile H, Funck-Brentano C, Lebrun-Vignes B (2019) Drug-induced aseptic meningitis: 329 cases from the French pharmacovigilance database analysis. Br J Clin Pharmacol 85:2540–2546. https://doi.org/10.1111/bcp.14073
doi: 10.1111/bcp.14073
pubmed: 31318079
pmcid: 6848896
Re VL 3rd, Gluckman SJ (2003) Eosinophilic meningitis. Am J Med 114:217–223. https://doi.org/10.1016/s0002-9343(02)01495-x
doi: 10.1016/s0002-9343(02)01495-x
pubmed: 12637136
Morell A (1986) Various immunoglobulin preparations for intravenous use. Vox Sang 51(Suppl 2):44–49. https://doi.org/10.1111/j.1423-0410.1986.tb02007.x
doi: 10.1111/j.1423-0410.1986.tb02007.x
pubmed: 2945321
Dantal J (2013) Intravenous immunoglobulins: in-depth review of excipients and acute kidney injury risk. Am J Nephrol 38(4):275–284. https://doi.org/10.1159/000354893
doi: 10.1159/000354893
pubmed: 24051350
Bagos-Estevez AG, Ledford DK (2022) Anaphylaxis: definition, epidemiology, diagnostic challenges, grading system. Immunol Allergy Clin North Am 42:1–11. https://doi.org/10.1016/j.iac.2021.09.001
doi: 10.1016/j.iac.2021.09.001
pubmed: 34823740
Lawley TJ, Bielory L, Gascon P, Yancey KB, Young NS, Frank MM (1984) A prospective clinical and immunologic analysis of patients with serum sickness. N Engl J Med 311:1407–1413. https://doi.org/10.1056/NEJM198411293112204
doi: 10.1056/NEJM198411293112204
pubmed: 6387492
Veranneman N, Van Raemdonck D, Dupont L, Verleden G (2010) Repeated, severe headache in a lung transplant patient: a case report. Acta Clin Belg 65:269–270. https://doi.org/10.1179/acb.2010.057
doi: 10.1179/acb.2010.057
pubmed: 20954467
Cherin P, Marie I, Michallet M, Pelus E, Dantal J, Crave JC, Delain JC, Viallard JF (2016) Management of adverse events in the treatment of patients with immunoglobulin therapy: a review of evidence. Autoimmun Rev 15:71–81. https://doi.org/10.1016/j.autrev.2015.09.002
doi: 10.1016/j.autrev.2015.09.002
pubmed: 26384525
Kretowska-Grunwald A, Krawczuk-Rybak M, Sawicka-Zukowska M (2022) Intravenous immunoglobulin-induced aseptic meningitis-a narrative review of the diagnostic process, pathogenesis, preventative measures and treatment. J Clin Med 11:3571. https://doi.org/10.3390/jcm11133571
doi: 10.3390/jcm11133571
pubmed: 35806861
pmcid: 9267278