How selective antagonists and genetic modification have helped characterise the expression and functions of vascular P2Y receptors.
AR-C118925XX
Atherosclerosis
Cangrelor
Hypertension
MRS2179
MRS2578
NF340
P2Y receptor
PPTN
Vasoconstriction
Vasodilation
Journal
Purinergic signalling
ISSN: 1573-9546
Titre abrégé: Purinergic Signal
Pays: Netherlands
ID NLM: 101250499
Informations de publication
Date de publication:
13 May 2024
13 May 2024
Historique:
received:
11
09
2023
accepted:
03
05
2024
medline:
14
5
2024
pubmed:
14
5
2024
entrez:
13
5
2024
Statut:
aheadofprint
Résumé
Vascular P2Y receptors mediate many effects, but the role of individual subtypes is often unclear. Here we discuss how subtype-selective antagonists and receptor knockout/knockdown have helped identify these roles in numerous species and vessels. P2Y
Identifiants
pubmed: 38740733
doi: 10.1007/s11302-024-10016-z
pii: 10.1007/s11302-024-10016-z
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024. The Author(s).
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Ritter JM, Flower RJ, Henderson G, Loke YK, MacEwan D, Robinson E, Fullerton J (2024) Rang & Dale's Pharmacology, 10