Redefining cerebellar assessment: A comprehensive review of the cerebellum's cognitive and affective roles and the efficacy of CCAS scales.

Cerebellar cognitive affective syndrome (CCAS) Cerebellar cognitive affective syndrome scale Cerebellum Mini-mental state examination (MMSE) Schmahmann’s syndrome

Journal

Surgical neurology international
ISSN: 2229-5097
Titre abrégé: Surg Neurol Int
Pays: United States
ID NLM: 101535836

Informations de publication

Date de publication:
2024
Historique:
received: 26 03 2024
accepted: 03 04 2024
medline: 14 5 2024
pubmed: 14 5 2024
entrez: 14 5 2024
Statut: epublish

Résumé

Emerging research expands our understanding of the cerebellum beyond motor control to include cognitive, emotional, and autonomic functions. This review examines the cerebellum's complex role, spotlighting Schmahmann's syndrome, or cerebellar cognitive affective syndrome (CCAS), which impairs executive functions, language, and spatial processing. It emphasizes advancements in diagnosing CCAS and the imperative of developing superior diagnostic tools for managing cerebellar pathologies effectively. A comprehensive literature search was performed using databases such as PubMed, OVID Embase, and OVID Medline. Using the keywords "cerebellar cognitive, affective syndrome" and "Schmahmann syndrome," the search was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines for systemic review, in which the selection process narrowed down an initial set of 54 articles to 12, focusing on the impact of the CCAS scale on diagnosing and understanding Schmahmann's syndrome. The review's analysis confirms the cerebellum's roles in motor and cognitive functions and underscores the CCAS scale as a significant advancement in detecting cerebellar deficits, surpassing traditional assessments such as the mini-mental state examination and Montreal cognitive assessment. This review emphasizes the importance of understanding the cerebellum's involvement in cognition and emotion and the crucial role of the CCAS scale for identifying cerebellar impairments. It calls for better diagnostic tools to assess CCAS accurately and suggests enhancing the CCAS Scale to reflect cultural and educational diversity. This will improve the diagnosis and treatment of cerebellar disorders, promoting a comprehensive neurological perspective on the cerebellum's functions.

Sections du résumé

Background UNASSIGNED
Emerging research expands our understanding of the cerebellum beyond motor control to include cognitive, emotional, and autonomic functions. This review examines the cerebellum's complex role, spotlighting Schmahmann's syndrome, or cerebellar cognitive affective syndrome (CCAS), which impairs executive functions, language, and spatial processing. It emphasizes advancements in diagnosing CCAS and the imperative of developing superior diagnostic tools for managing cerebellar pathologies effectively.
Methods UNASSIGNED
A comprehensive literature search was performed using databases such as PubMed, OVID Embase, and OVID Medline. Using the keywords "cerebellar cognitive, affective syndrome" and "Schmahmann syndrome," the search was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines for systemic review, in which the selection process narrowed down an initial set of 54 articles to 12, focusing on the impact of the CCAS scale on diagnosing and understanding Schmahmann's syndrome.
Results UNASSIGNED
The review's analysis confirms the cerebellum's roles in motor and cognitive functions and underscores the CCAS scale as a significant advancement in detecting cerebellar deficits, surpassing traditional assessments such as the mini-mental state examination and Montreal cognitive assessment.
Conclusion UNASSIGNED
This review emphasizes the importance of understanding the cerebellum's involvement in cognition and emotion and the crucial role of the CCAS scale for identifying cerebellar impairments. It calls for better diagnostic tools to assess CCAS accurately and suggests enhancing the CCAS Scale to reflect cultural and educational diversity. This will improve the diagnosis and treatment of cerebellar disorders, promoting a comprehensive neurological perspective on the cerebellum's functions.

Identifiants

DOI: 10.25259/SNI_226_2024 PMID: 38742008 PMC: PMC11090570
pubmed: 38742008
doi: 10.25259/SNI_226_2024
pii: 10.25259/SNI_226_2024
pmc: PMC11090570
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

141

Informations de copyright

Copyright: © 2024 Surgical Neurology International.

Déclaration de conflit d'intérêts

There are no conflicts of interest

Auteurs

Albert Alan (A)

Global Neurosurgical Alliance, Tucson, Arizona, United States.
College of Medicine, The University of Arizona College of Medicine - Tucson, Arizona, United States.
Department of Neurosurgery, University of Arizona, Tucson, Arizona, United States.

Michelle Ennabe (M)

Global Neurosurgical Alliance, Tucson, Arizona, United States.
College of Medicine, The University of Arizona College of Medicine - Phoenix, Arizona, United States.

Muath Alsarafandi (M)

Global Neurosurgical Alliance, Tucson, Arizona, United States.
Faculty of Medicine, Islamic University of Gaza, Gaza, Palestine, Palestinian Territory, Occupied.
College of Medicine, Islamic University of Gaza, Rafah Refugee Camp, Rafah, Palestinian Territory, Occupied.

Noor Malik (N)

Global Neurosurgical Alliance, Tucson, Arizona, United States.
Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota, United States.

Edward R Laws (ER)

Professor of Neurosurgery, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts, United States.

Martin Weinand (M)

College of Medicine, The University of Arizona College of Medicine - Tucson, Arizona, United States.
Department of Neurosurgery, University of Arizona, Tucson, Arizona, United States.

Classifications MeSH