SPRING is a Dedicated Licensing Factor for SREBP-Specific Activation by S1P.

C12ORF49 Cholesterol metabolism S1P SPRING SREBP cholesterol regulation lipid metabolism post-transcriptional regulation proteolysis proteolytic enzyme

Journal

Molecular and cellular biology
ISSN: 1098-5549
Titre abrégé: Mol Cell Biol
Pays: United States
ID NLM: 8109087

Informations de publication

Date de publication:
15 May 2024
Historique:
medline: 15 5 2024
pubmed: 15 5 2024
entrez: 15 5 2024
Statut: aheadofprint

Résumé

SREBP transcription factors are central regulators of lipid metabolism. Their proteolytic activation requires ER to the Golgi translocation and subsequent cleavage by site-1-protease (S1P). Produced as a proprotein, S1P undergoes autocatalytic cleavage from its precursor S1P

Identifiants

DOI: 10.1080/10985549.2024.2348711 PMID: 38747374
pubmed: 38747374
doi: 10.1080/10985549.2024.2348711
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-15

Auteurs

Sebastian Hendrix (S)

Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Amsterdam, The Netherlands.
ORCID: 0000-0003-2055-9883

Josephine M E Tan (JME)

Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Amsterdam, The Netherlands.
ORCID: 0000-0003-2534-3029

Klevis Ndoj (K)

Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Amsterdam, The Netherlands.
ORCID: 0009-0002-5902-7673

Jenina Kingma (J)

Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Amsterdam, The Netherlands.
ORCID: 0000-0003-2822-5415

Masoud Valiloo (M)

Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Amsterdam, The Netherlands.

Lobke F Zijlstra (LF)

Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Amsterdam, The Netherlands.
ORCID: 0009-0008-9698-4046

Roelof Ottenhoff (R)

Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Amsterdam, The Netherlands.
ORCID: 0000-0003-3023-1128

Nabil G Seidah (NG)

Laboratory of Biochemical Neuroendocrinology, Montreal Clinical Research Institute (IRCM), University of Montreal, Montréal, Québec, Canada.
ORCID: 0000-0001-6503-9342

Anke Loregger (A)

Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Amsterdam, The Netherlands.

Daniel L Kober (DL)

Department of Biochemistry, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.
ORCID: 0000-0001-8657-9348

Noam Zelcer (N)

Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Amsterdam, The Netherlands.
ORCID: 0000-0001-6935-7532

Classifications MeSH