Choroidal arterial abnormality in central serous chorioretinopathy.

Arteriovenous shunt Central serous chorioretinopathy Pachychoroid neovasculopathy Pachychoroid spectrum disease Ultrawide-field indocyanine green angiography

Journal

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

ISSN: 1435-702X

Titre abrégé: Graefes Arch Clin Exp Ophthalmol

Pays: Germany

ID NLM: 8205248

Informations de publication

Date de publication:
15 May 2024

Historique:

received: 15 01 2024

accepted: 09 05 2024

revised: 11 04 2024

medline: 15 5 2024

pubmed: 15 5 2024

entrez: 15 5 2024

Statut: aheadofprint

Résumé

To evaluate the choroidal arterial abnormality in central serous chorioretinopathy (CSC). Fifty-two eyes from 52 patients with CSC were retrospectively evaluated. Arterial and venous ultrawide-field indocyanine green angiography were merged after color and transparency adjustments to compare the choroidal arterial and venous vasculature. Specifically, we evaluated whether the choroidal arteries directly fill the pachyvessel without interconnection of choriocapillaris (arterial pachyvessel; aPV). Then, the clinical characteristics of patients with and without arterial pachyvessel were compared. Pachyvessel under subretinal fluid was detected in 47 of 52 eyes (90.4%). An arterial pachyvessel was detected in eight of 52 eyes (15.4%). Of those eight eyes with arterial pachyvessel, seven (87.5%) showed sustained staining through the venous phase, suggesting they are arteriovenous shunt, while one eye (12.5%) showed diminished fluorescence in the venous phase, suggesting this pachyvessel was purely an artery. Patients with arterial pachyvessel experienced more CSC recurrences (non-aPV group: 2.09 ± 1.44 times vs. aPV group: 3.25 ± 1.28 times; p = 0.039) and pachychoroid neovasculopathy (PNV) development (non-aPV group: 2.3% vs. aPV group: 37.5%, p = 0.009). The presence of arterial pachyvessel in eyes with CSC may represent choroidal circulatory imbalance and focal shear stress to Bruch's membrane, leading to a chronic nature and PNV development.

Identifiants

DOI: 10.1007/s00417-024-06522-w PMID: 38748212

pubmed: 38748212

doi: 10.1007/s00417-024-06522-w

pii: 10.1007/s00417-024-06522-w

doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

Informations de copyright

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