Axillary Management: How Much Is Too Much?

Axilla Breast Cancer Neoadjuvant Systemic Therapy Nodal Irradiation Surgery

Journal

Current oncology reports
ISSN: 1534-6269
Titre abrégé: Curr Oncol Rep
Pays: United States
ID NLM: 100888967

Informations de publication

Date de publication:
15 May 2024
Historique:
accepted: 29 04 2024
medline: 15 5 2024
pubmed: 15 5 2024
entrez: 15 5 2024
Statut: aheadofprint

Résumé

To review the current management of the axilla in breast cancer. Axillary dissection is no longer indicated in patients with clinically node-negative axilla with 1-2 positive sentinel lymph nodes following upfront surgery or in patients with clinically node-negative axilla following neoadjuvant chemotherapy. Breast cancer has evolved away from routine axillary clearance to the less invasive sentinel lymph node biopsy to now complete omission of axillary sampling in select patients. We will review the most salient evidence that has shaped these practice changes over the last three decades. Current practice controversies are especially relevant for elderly populations and those receiving neoadjuvant therapy. Ongoing clinical trials will provide data to further guide breast cancer surgical management.

Identifiants

pubmed: 38748364
doi: 10.1007/s11912-024-01539-0
pii: 10.1007/s11912-024-01539-0
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s).

Auteurs

Nicci Owusu-Brackett (N)

Division of Surgical Oncology, Department of Surgery, The Ohio State University Wexner Medical Center and James Cancer Hospital, Columbus, OH, USA.

Benjin Facer (B)

Department of Radiation Oncology, The Ohio State University Wexner Medical Center and James Cancer Hospital, Columbus, OH, USA.

Dionisia Quiroga (D)

Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Wexner Medical Center and James Cancer Hospital, Columbus, OH, USA.

Ashley Pariser (A)

Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Wexner Medical Center and James Cancer Hospital, Columbus, OH, USA.

Michael Grimm (M)

West Virginia University School of Medicine, Morgantown, WV, USA.

Sasha Beyer (S)

Department of Radiation Oncology, The Ohio State University Wexner Medical Center and James Cancer Hospital, Columbus, OH, USA.

Sachin Jhawar (S)

Department of Radiation Oncology, The Ohio State University Wexner Medical Center and James Cancer Hospital, Columbus, OH, USA.

Bridget A Oppong (BA)

Division of Surgical Oncology, Department of Surgery, The Ohio State University Wexner Medical Center and James Cancer Hospital, Columbus, OH, USA. bridget.oppong@osumc.edu.

Classifications MeSH