Fusion Harboring Mast Cells Can Explain Molecular Positivity in Flow Cytometric MRD Negative Core Binding Factor AML.


Journal

Blood
ISSN: 1528-0020
Titre abrégé: Blood
Pays: United States
ID NLM: 7603509

Informations de publication

Date de publication:
15 May 2024
Historique:
accepted: 09 05 2024
received: 01 03 2024
revised: 25 04 2024
medline: 15 5 2024
pubmed: 15 5 2024
entrez: 15 5 2024
Statut: aheadofprint

Résumé

Molecular measurable residual disease (MRD) can persist in core binding factor acute myeloid leukemia (AML) in otherwise disease-free patients. Utilizing cell sorting followed by fluorescent in situ hybridization, we show that detection is due to mast cells.

Identifiants

pubmed: 38749014
pii: 516115
doi: 10.1182/blood.2024024264
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024 American Society of Hematology.

Auteurs

Jacqueline A Cook (JA)

Hematologics, Inc., Seattle, Washington, United States.

Loren Lott (L)

Hematologics, Inc., Seattle, Washington, United States.

Jenna Perry (J)

Hematologics, Inc., Seattle, Washington, United States.

Ashley M Eckel (AM)

Hematologics, Inc., Seattle, Washington, United States.

Dongbin Xu (D)

Hematologics, Inc., Seattle, Washington, United States.

Chad A Hudson (CA)

Hematologics, Inc., Seattle, Washington, United States.

Denise A Wells (DA)

Hematologics, Inc., Seattle, Washington, United States.

Michael R Loken (MR)

HematoLogics Inc, Seattle, Washington, United States.

Andrew J Menssen (AJ)

Hematologics, Inc., Seattle, Washington, United States.

Classifications MeSH