Implications for driving based on the risk of seizures after ischaemic stroke.

Activities of Daily Living CLINICAL NEUROLOGY EPILEPSY STROKE

Journal

Journal of neurology, neurosurgery, and psychiatry
ISSN: 1468-330X
Titre abrégé: J Neurol Neurosurg Psychiatry
Pays: England
ID NLM: 2985191R

Informations de publication

Date de publication:
15 May 2024
Historique:
received: 29 01 2024
accepted: 14 04 2024
medline: 16 5 2024
pubmed: 16 5 2024
entrez: 15 5 2024
Statut: aheadofprint

Résumé

In addition to other stroke-related deficits, the risk of seizures may impact driving ability after stroke. We analysed data from a multicentre international cohort, including 4452 adults with acute ischaemic stroke and no prior seizures. We calculated the Chance of Occurrence of Seizure in the next Year (COSY) according to the SeLECT Seizure risks in the next year were mainly influenced by the baseline risk-stratified according to the SeLECT Personalised prognostic models, such as SeLECT

Sections du résumé

BACKGROUND BACKGROUND
In addition to other stroke-related deficits, the risk of seizures may impact driving ability after stroke.
METHODS METHODS
We analysed data from a multicentre international cohort, including 4452 adults with acute ischaemic stroke and no prior seizures. We calculated the Chance of Occurrence of Seizure in the next Year (COSY) according to the SeLECT
RESULTS RESULTS
Seizure risks in the next year were mainly influenced by the baseline risk-stratified according to the SeLECT
CONCLUSIONS CONCLUSIONS
Personalised prognostic models, such as SeLECT

Identifiants

pubmed: 38749674
pii: jnnp-2024-333505
doi: 10.1136/jnnp-2024-333505
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: LA has received personal fees and travel support from UCB Pharma, Eisai, Esteve and Bial and personal fees from Sanofi outside the submitted work. ES has received grants and personal fees from UCB Pharma, Eisai, Esteve and Bial, outside the submitted work. SE received honoraria for consulting and lectures from Allergan/Abbvie, Lilly, Lundbeck, Novartis, Perfood, Teva (past 3 years). FB received fees and travel support from Lusofarmaco, outside the submitted work. CB received a Grant from Sociedade Portuguesa do AVC (sponsored by Tecnifar), honoraria for lectures and support for scientific events from Bial, outside the submitted work. MK received non-financial support from ROCHE and BRAHMS Thermofisher Scientific outside the submitted work. MRK reports grants from UCB and Eisai, outside of the submitted work. BT reports personal fees from Biogen outside the submitted work. JWS reports grants and personal fees from UCB, grants from NIHR and Angelini; and personal fees from UCB and Angelini outside the submitted work. MG received fees and travel support from Arvelle, Advisis, Bial and Nestlé Health Science outside the submitted work. JNW received fees from Boehringer Ingelheim and UCB and travel grants from ROCHE, outside the submitted work. TJvO reports personal fees from Angelini Pharma Österreich; Arvelle Therapeutics, Argenx, Biogen, Eisai GesmbH, GW Pharma, Jazz Pharmaceuticals, LivaNova, und von Zogenix, grants from Boehringer-Ingelheim, outside the submitted work. All other authors declare no competing interests.

Auteurs

Kai Michael Schubert (KM)

Department of Neurology, Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland.

Giulio Bicciato (G)

Department of Neurology, Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland.

Lucia Sinka (L)

Department of Neurology, Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland.
Department of Neurology, Schulthess Klinik, Zurich, Switzerland.

Laura Abraira (L)

Epilepsy Unit, Department of Neurology, Vall d'Hebron University Hospital, Barcelona, Universitat Autonoma de Barcelona, Bellaterra, Spain.

Estevo Santamarina (E)

Epilepsy Unit, Department of Neurology, Vall d'Hebron University Hospital, Barcelona, Universitat Autonoma de Barcelona, Bellaterra, Spain.

José Álvarez-Sabín (J)

Epilepsy Unit, Department of Neurology, Vall d'Hebron University Hospital, Barcelona, Universitat Autonoma de Barcelona, Bellaterra, Spain.

Carolina Ferreira-Atuesta (C)

Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London WC1N 3BG & Chalfont Centre for Epilepsy, Chalfont St Peter SL9 0RJ, UK.
Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.

Mira Katan (M)

Department of Neurology, Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland.
Department of Neurology, University Hospital and University of Basel, Basel, Switzerland.

Natalie Scherrer (N)

Department of Neurology, Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland.

Robert Terziev (R)

Department of Neurology, Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland.

Nico Döhler (N)

Department of Neurology, Kantonsspital St Gallen, Sankt Gallen, Switzerland.
Specialist Clinic for Neurorehabilitation, Beelitz Hospitals, Beelitz, Germany.

Barbara Erdélyi-Canavese (B)

Department of Neurology, Kantonsspital St Gallen, Sankt Gallen, Switzerland.

Ansgar Felbecker (A)

Department of Neurology, Kantonsspital St Gallen, Sankt Gallen, Switzerland.

Philip Siebel (P)

Department of Neurology, Kantonsspital St Gallen, Sankt Gallen, Switzerland.

Michael Winklehner (M)

Department of Neurology, Kepler University Hospital, Johannes Kepler Universitat Linz, Linz, Austria.

Tim J von Oertzen (TJ)

Department of Neurology, Kepler University Hospital, Johannes Kepler Universitat Linz, Linz, Austria.

Judith N Wagner (JN)

Department of Neurology, Kepler University Hospital, Johannes Kepler Universitat Linz, Linz, Austria.
Department of Neurology, Evangelisches Klinikum Gelsenkirchen, Academic Hospital University Essen-Duisburg, Gelsenkirchen, Germany.

Gian Luigi Gigli (GL)

Department of Medicine, University of Udine and Clinical Neurology, University of Udine, Udine, Italy.

Annacarmen Nilo (A)

Department of Medicine, University of Udine and Clinical Neurology, University of Udine, Udine, Italy.

Francesco Janes (F)

Department of Medicine, University of Udine and Clinical Neurology, University of Udine, Udine, Italy.

Giovanni Merlino (G)

Department of Medicine, University of Udine and Clinical Neurology, University of Udine, Udine, Italy.

Mariarosaria Valente (M)

Department of Medicine, University of Udine and Clinical Neurology, University of Udine, Udine, Italy.

María Paula Zafra-Sierra (MP)

Department of Neurology, Fundación Santa Fe de Bogotá, Universidad de Los Andes, Universidad del Bosque, Bogota, Colombia.

Luis Carlos Mayor-Romero (LC)

Department of Neurology, Fundación Santa Fe de Bogotá, Universidad de Los Andes, Universidad del Bosque, Bogota, Colombia.

Julian Conrad (J)

Department of Neurology, University of Münster, Munster, Germany.
Division for Neurodegenerative Diseases, Department of Neurology, Universitaetsmedizin Mannheim, Heidelberg University, Heidelberg, Germany.

S Evers (S)

Department of Neurology, University of Münster, Munster, Germany.
Department of Neurology, Krankenhaus Lindenbrunn, Coppenbrugge, Germany.

Piergiorgio Lochner (P)

Department of Neurology, Saarland University Medical Center, Homburg, Germany.

Frauke Roell (F)

Department of Neurology, Saarland University Medical Center, Homburg, Germany.

Francesco Brigo (F)

Department of Neurology, Hospital Merano (SABES-ASDAA), Merano-Meran, Italy.

Carla Bentes (C)

Department of Neurosciences and Mental Health (Neurology), Hospital de Santa Maria-CHULN. Centro de Estudos Egas Moniz, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.

Rita Peralta (R)

Department of Neurosciences and Mental Health (Neurology), Hospital de Santa Maria-CHULN. Centro de Estudos Egas Moniz, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.

Teresa Pinho E Melo (T)

Department of Neurosciences and Mental Health (Neurology), Hospital de Santa Maria-CHULN. Centro de Estudos Egas Moniz, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.

Mark R Keezer (MR)

Stichting Epilepsie Instellingen Nederland -(SEIN), Heemstede 2103 SW, The Netherlands.
Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.

John Sidney Duncan (JS)

Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London WC1N 3BG & Chalfont Centre for Epilepsy, Chalfont St Peter SL9 0RJ, UK.

Josemir W Sander (JW)

Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London WC1N 3BG & Chalfont Centre for Epilepsy, Chalfont St Peter SL9 0RJ, UK.
Stichting Epilepsie Instellingen Nederland -(SEIN), Heemstede 2103 SW, The Netherlands.
Department of Neurology, West China Hospital, Sichuan University, Chengdu 61004, China.

Barbara Tettenborn (B)

Department of Neurology, Kantonsspital St Gallen, Sankt Gallen, Switzerland.

Matthias Koepp (M)

Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London WC1N 3BG & Chalfont Centre for Epilepsy, Chalfont St Peter SL9 0RJ, UK.

Marian Galovic (M)

Department of Neurology, Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland marian.galovic@usz.ch.
Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London WC1N 3BG & Chalfont Centre for Epilepsy, Chalfont St Peter SL9 0RJ, UK.

Classifications MeSH