Structure, chemical modification, and functional applications of mucilage from Mimosa pudica seeds - A review.

Acetylation Crosslinking Drug release formulations Mimosa pudica, mucilage Nanoparticles Succinylation Wound healing

Journal

International journal of biological macromolecules
ISSN: 1879-0003
Titre abrégé: Int J Biol Macromol
Pays: Netherlands
ID NLM: 7909578

Informations de publication

Date de publication:
14 May 2024
Historique:
received: 29 09 2023
revised: 28 04 2024
accepted: 13 05 2024
medline: 17 5 2024
pubmed: 17 5 2024
entrez: 16 5 2024
Statut: aheadofprint

Résumé

Mimosa pudica (MP) is an ornamental plant due to seismonastic movements that close leaves and fall petioles in response to touch, wind, light, heat, cold, and vibration. The seeds of MP secrete smart, biocompatible, and non-toxic mucilage that has captivated researchers due to its widespread use in various fields such as pharmaceuticals and biotechnology. The mucilage is responsive to pH, salt solutions, and solvents and acts as a binder in tablet formulations for targeted drug delivery. The mucilage is chemically modifiable via acetylation, succinylation, and graft polymerization. Chemically modified MP mucilage appeared supersorbent for heavy metal ion uptake. Nanoparticles synthesized using mucilage as a reducing and capping agent displayed significant antimicrobial and wound-healing potential. Crosslinking of mucilage using citric acid as a crosslinking agent offers a sustained release of drugs. The present review is aimed to discuss extraction optimization, structure, modification, and the stimuli-responsive nature of mucilage. The review article will cover the potential of mucilage as emulsifying, suspending, bio-adhesive, gelling, and thickening agent. The role of mucilage as a capping and reducing agent for nanoparticles will also be discussed.

Identifiants

pubmed: 38754657
pii: S0141-8130(24)03195-7
doi: 10.1016/j.ijbiomac.2024.132390
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

132390

Informations de copyright

Copyright © 2024. Published by Elsevier B.V.

Déclaration de conflit d'intérêts

Declaration of competing interest There are no conflicts of interest to declare.

Auteurs

Manahil Noor (M)

Department of Chemistry, Government College University, Lahore 54000, Pakistan.

Gulzar Muhammad (G)

Department of Chemistry, Government College University, Lahore 54000, Pakistan. Electronic address: mgulzar@gcu.edu.pk.

Hina Hanif (H)

Department of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan.

Muhammad Ajaz Hussain (MA)

Centre for Organic Chemistry, School of Chemistry, University of the Punjab, Lahore 54590, Pakistan.

Muhammad Mudassir Iqbal (MM)

Department of Chemistry, Superior University Lahore, Lahore, Pakistan.

Uqba Mehmood (U)

Department of Biological Sciences, Superior University, Lahore, Pakistan.

Parham Taslimi (P)

Department of Biotechnology, Faculty of Science, Bartin University, 74100 Bartin, Turkey.

Zahid Shafiq (Z)

Department of Pharmaceutical & Medicinal Chemistry, An der Immenburg 4, D-53121 Bonn, Germany; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan. Electronic address: zahidshafiq@bzu.edu.pk.

Classifications MeSH