Asciminib monotherapy in patients with chronic-phase chronic myeloid leukemia with the T315I mutation after ≥1 prior tyrosine kinase inhibitor: 2-year follow-up results.


Journal

Leukemia
ISSN: 1476-5551
Titre abrégé: Leukemia
Pays: England
ID NLM: 8704895

Informations de publication

Date de publication:
16 May 2024
Historique:
received: 08 03 2024
accepted: 02 05 2024
revised: 01 05 2024
medline: 17 5 2024
pubmed: 17 5 2024
entrez: 16 5 2024
Statut: aheadofprint

Résumé

Asciminib targets the BCR::ABL1 myristoyl pocket, maintaining activity against BCR::ABL1

Identifiants

pubmed: 38755421
doi: 10.1038/s41375-024-02278-8
pii: 10.1038/s41375-024-02278-8
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s).

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Auteurs

Jorge E Cortes (JE)

Georgia Cancer Center at Augusta University, Augusta, GA, USA. Jorge.Cortes@Augusta.edu.

Koji Sasaki (K)

Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Dong-Wook Kim (DW)

Uijeongbu Eulji Medical Center, Geumo-dong, Uijeongbu-si, South Korea.

Timothy P Hughes (TP)

South Australian Health and Medical Research Institute and University of Adelaide, Adelaide, SA, Australia.

Gabriel Etienne (G)

Department of Hematology, Institut Bergonié, Bordeaux, France.

Michael J Mauro (MJ)

Myeloproliferative Neoplasms Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Andreas Hochhaus (A)

Hematology/Oncology, Universitätsklinikum Jena, Jena, Germany.

Fabian Lang (F)

Department of Medicine, Hematology and Oncology, Goethe University Hospital, Frankfurt, Germany.

Michael C Heinrich (MC)

Portland VA Health Care System and OHSU Department of Medicine, Division of Hematology and Oncology, Knight Cancer Institute, Portland, OR, USA.

Massimo Breccia (M)

Department of Translational and Precision Medicine-Az., Policlinico Umberto I-Sapienza University, Rome, Italy.

Michael Deininger (M)

Versiti Blood Research Institute, Milwaukee, WI, USA.

Yeow Tee Goh (YT)

Department of Haematology, Singapore General Hospital, Bukit Merah, Singapore.

Jeroen J W M Janssen (JJWM)

Radboud University Medical Center, Nijmegen, The Netherlands.

Moshe Talpaz (M)

Division of Hematology-Oncology, University of Michigan Rogel Cancer Center, Ann Arbor, MI, USA.

Valle Gomez Garcia de Soria (VGG)

Hospital Universitario La Princesa, Madrid, Spain.

Philipp le Coutre (P)

Department of Oncology and Hematology, Charité - Universitätsmedizin Berlin, Berlin, Germany.

Daniel J DeAngelo (DJ)

Dana-Farber Cancer Institute, Boston, MA, USA.

Andrea Damon (A)

Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA.

Silvia Cacciatore (S)

Novartis Pharma AG, Basel, Switzerland.

Fotis Polydoros (F)

Novartis Pharma AG, Basel, Switzerland.

Nithya Agrawal (N)

Novartis Pharma AG, Basel, Switzerland.

Delphine Rea (D)

Department of Hématologie, Hôpital Saint-Louis, Paris, France.

Classifications MeSH