Neurotransmitter accumulation and Parkinson's disease-like phenotype caused by anion channelrhodopsin opto-controlled astrocytic mitochondrial depolarization in substantia nigra pars compacta.

GABA Parkinson's Disease anion channelrhodopsin astrocyte glutamate mitochondria optogenetics

Journal

MedComm
ISSN: 2688-2663
Titre abrégé: MedComm (2020)
Pays: China
ID NLM: 101769925

Informations de publication

Date de publication:
Jun 2024
Historique:
received: 21 11 2023
revised: 28 03 2024
accepted: 01 04 2024
medline: 17 5 2024
pubmed: 17 5 2024
entrez: 17 5 2024
Statut: epublish

Résumé

Parkinson's disease (PD) is a mitochondria-related neurodegenerative disease characterized by locomotor deficits and loss of dopaminergic (DA) neurons in the

Identifiants

pubmed: 38756440
doi: 10.1002/mco2.568
pii: MCO2568
pmc: PMC11094672
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e568

Informations de copyright

© 2024 The Authors. MedComm published by Sichuan International Medical Exchange & Promotion Association (SCIMEA) and John Wiley & Sons Australia, Ltd.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Auteurs

Sen-Miao Li (SM)

Clinical Systems Biology Laboratories The First Affiliated Hospital of Zhengzhou University Zhengzhou China.
Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.
The Academy of Medical Sciences Zhengzhou University Zhengzhou China.

Dian-Dian Wang (DD)

Clinical Systems Biology Laboratories The First Affiliated Hospital of Zhengzhou University Zhengzhou China.
Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.
The Academy of Medical Sciences Zhengzhou University Zhengzhou China.

Dan-Hua Liu (DH)

Clinical Systems Biology Laboratories The First Affiliated Hospital of Zhengzhou University Zhengzhou China.
Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.
The Academy of Medical Sciences Zhengzhou University Zhengzhou China.

Xiao-Yan Meng (XY)

Clinical Systems Biology Laboratories The First Affiliated Hospital of Zhengzhou University Zhengzhou China.
Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.
The Academy of Medical Sciences Zhengzhou University Zhengzhou China.

Zhizhong Wang (Z)

College of Electrical and Information Engineering Zhengzhou University Zhengzhou China.

Xitong Guo (X)

Zhengzhou University of Technology Zhengzhou China.

Qian Liu (Q)

North China University of Water Resources and Electric Power Zhengzhou China.

Pei-Pei Liu (PP)

Clinical Systems Biology Laboratories The First Affiliated Hospital of Zhengzhou University Zhengzhou China.

Shu-Ang Li (SA)

Clinical Systems Biology Laboratories The First Affiliated Hospital of Zhengzhou University Zhengzhou China.

Songwei Wang (S)

College of Electrical and Information Engineering Zhengzhou University Zhengzhou China.

Run-Zhou Yang (RZ)

Clinical Systems Biology Laboratories The First Affiliated Hospital of Zhengzhou University Zhengzhou China.

Yuming Xu (Y)

Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.
NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou University Zhengzhou China.
Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China.

Longde Wang (L)

Department of Neurology The First Affiliated Hospital of Zhengzhou University Zhengzhou China.
NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Disease Zhengzhou University Zhengzhou China.
Henan Key Laboratory of Cerebrovascular Diseases Zhengzhou University Zhengzhou China.

Jian-Sheng Kang (JS)

Clinical Systems Biology Laboratories The First Affiliated Hospital of Zhengzhou University Zhengzhou China.

Classifications MeSH