Two- and three-dimensional healing assessment after endodontic microsurgery in through-and-through periapical lesions: 5-year follow-up from a randomized controlled trial.
5‐year outcome
CBCT (cone beam computed tomography)
healing
periapical surgery
platelet‐rich plasma (PRP)
through‐and‐through lesions
Journal
International endodontic journal
ISSN: 1365-2591
Titre abrégé: Int Endod J
Pays: England
ID NLM: 8004996
Informations de publication
Date de publication:
17 May 2024
17 May 2024
Historique:
revised:
19
03
2024
received:
13
02
2024
accepted:
03
05
2024
medline:
17
5
2024
pubmed:
17
5
2024
entrez:
17
5
2024
Statut:
aheadofprint
Résumé
To evaluate clinical and radiographic outcome of endodontic microsurgery in through-and-through periapical lesions at 1-year and 5-year follow-up with adjunct use of platelet-rich plasma (PRP). Thirty-two patients with large through-and-through periapical lesions were randomized in platelet-rich plasma (PRP) group and control group. Two-dimensional (2D) healing was evaluated with Molven's criteria and three-dimensional (3D) healing with modified PENN 3D criteria. Healing at resection plane (R), apical area (A), buccal cortex (BC), palatal cortex (PC) and overall bone healing (B) was assessed using CBCT scans. The volume of lesion was measured using ITK-Snap software. The analysis included comparison of 1- to 5-year intragroup (Friedman test/McNemar test) and intergroup scoring (Chi-square/ Mann-Whitney test). Logistic regression analysis was performed to determine the effect of various factors on healing at 5 years. Out of 32 patients/59 teeth evaluated after 1-year of endodontic microsurgery, 24 patients/44 teeth reported at 5 - year follow-up. Healing assessment with modified PENN 3D criteria revealed improvement in overall success rate of 66.7% at 1 year to 83.3% at 5 years, with no deterioration in any healing category. PRP group exhibited significantly better 3D healing than control group; both at 1 year (84.6% vs. 45.5%) and 5 years (100% vs. 63.6%). A significantly higher number of completely healed teeth were observed in PRP group than the control group at 5 years with respect to R, BC and B parameters. A volume reduction of 88% (91.4% PRP, 84% control) was depicted at 1 year and 94% (97.1% PRP, 91.1% control) at 5 years. None of the recorded factors including age, gender, size of lesion, preoperative swelling and sinus, histology of lesion, use of PRP, tooth location, preoperative buccal bone had significant effect on 3D healing at 5 years. This 5-year study suggested improvement in 3D radiographic healing of large through-and-through periapical lesions from 1 to 5 years with no deterioration in any healing parameter in both control and PRP groups. The additional use of PRP led to significantly better healing in such lesions. RACB index using CBCT allows better estimation of healing at resected, apical and cortical plane over modified PENN 3D or Molven's criteria.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024 British Endodontic Society. Published by John Wiley & Sons Ltd.
Références
Arpitha, M., Tewari, S., Sangwan, P. & Gupta, A. (2023) Efficacy of mixture of injectable‐platelet‐rich fibrin and type‐1 collagen particles on the closure of through‐and‐through periapical bone defects: a randomized controlled trial. International Endodontic Journal, 56, 1197–1211.
Azim, A.A., Albanyan, H., Azim, K.A. & Piasecki, L. (2021) The Buffalo study: outcome and associated predictors in endodontic microsurgery‐ a cohort study. International Endodontic Journal, 54, 301–318.
Bajaj, P., Pradeep, A.R., Agarwal, E., Rao, N.S., Naik, S.B., Priyanka, N. et al. (2013) Comparative evaluation of autologous platelet‐rich fibrin and platelet‐rich plasma in the treatment of mandibular degree II furcation defects: a randomized controlled clinical trial. Journal of Periodontal Research, 48, 573–581.
Chen, I., Karabucak, B., Wang, C., Wang, H.G., Koyama, E., Kohli, M.R. et al. (2015) Healing after root‐end microsurgery by using mineral trioxide aggregate and a new calcium silicate‐based bioceramic material as root‐end filling materials in dogs. Journal of Endodontics, 41, 389–399.
Chen, Y. & Shen, J. (2016) Clinical observation of GTR combined with bone grafting in endodontic microsurgery. Journal of Oral Science Research, 32, 1269.
Chong, B.S., Pitt Ford, T.R. & Hudson, M.B. (2003) A prospective clinical study of mineral trioxide aggregate and IRM when used as root‐end filling materials in endodontic surgery. International Endodontic Journal, 36, 520–526.
Christiansen, R., Kirkevang, L.L., Gotfredsen, E. & Wenzel, A. (2009) Periapical radiography and cone beam computed tomography for assessment of the periapical bone defect 1 week and 12 months after root‐end resection. Dento Maxillo Facial Radiology, 38, 531–536.
Curtis, D.M., VanderWeele, R.A., Ray, J.J. & Wealleans, J.A. (2018) Clinician‐centered outcomes assessment of retreatment and endodontic microsurgery using cone‐beam computed tomographic volumetric analysis. Journal of Endodontics, 44(8), 1251–1256.
Deng, Y., Zhu, X., Yang, J., Jiang, H. & Yan, P. (2016) The effect of regeneration techniques on periapical surgery with different protocols for different lesion types: a meta‐analysis. Journal of Oral and Maxillofacial Surgery, 74, 239–246.
Dhamija, R., Tewari, S., Sangwan, P., Duhan, J. & Mittal, S. (2020) Impact of platelet‐rich plasma in the healing of through‐and‐through periapical lesions using 2‐dimensional and 3‐dimensional evaluation: a randomized controlled trial. Journal of Endodontics, 46, 1167–1184.
Dhiman, M., Kumar, S., Duhan, J., Sangwan, P. & Tewari, S. (2015) Effect of platelet‐rich fibrin on healing of apicomarginal defects: a randomized controlled trial. Journal of Endodontics, 41, 985–991.
European Society of Endodontology. (1994) Consensus report of the European Society of Endodontology on quality guidelines for endodontic treatment. International Endodontic Journal, 27, 115–124.
Goyal, B., Tewari, S., Duhan, J. & Sehgal, P.K. (2011) Comparative evaluation of platelet‐rich plasma and guided tissue regeneration membrane in the healing of apicomarginal defects: a clinical study. Journal of Endodontics, 37, 773–780.
Grung, B., Molven, O. & Halse, A. (1990) Periapical surgery in a Norwegian county hospital: follow‐up findings of 477 teeth. Journal of Endodontics, 16, 411–417.
Hirsch, J.M., Ahlström, U., Henrikson, P.A., Heyden, G. & Peterson, L.E. (1979) Periapical surgery. International Journal of Oral Surgery, 8, 173–185.
Huang, S., Chen, N.N., Yu, V.S.H., Lim, H.A. & Lui, J.N. (2020) Long‐term success and survival of endodontic microsurgery. Journal of Endodontics, 46, 149–157.
Jesslén, P., Zetterqvist, L. & Heimdahl, A. (1995) Long‐term results of amalgam versus glass ionomer cement as apical sealant after apicectomy. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics, 79, 101–103.
Kim, D., Ku, H., Nam, T., Yoon, T.C., Lee, C.Y. & Kim, E. (2016) Influence of size and volume of periapical lesions on the outcome of endodontic microsurgery: 3‐dimensional analysis using cone‐beam computed tomography. Journal of Endodontics, 42, 1196–1201.
Kim, S., Song, M., Shin, S.J. & Kim, E. (2016) A randomized controlled study of mineral trioxide aggregate and super ethoxybenzoic acid as root‐end filling materials in endodontic microsurgery: long‐term outcomes. Journal of Endodontics, 42, 997–1002.
Kreisler, M., Gockel, R., Aubell‐Falkenberg, S., Kreisler, T., Weihe, C., Filippi, A. et al. (2013) Clinical outcome in periradicular surgery: effect of patient‐ and tooth‐related factors—a multicenter study. Quintessence International, 44, 53–60.
Kruse, C., Spin‐Neto, R., Christiansen, R., Wenzel, A. & Kirkevang, L.L. (2016) Periapical bone healing after apicectomy with and without retrograde root filling with mineral trioxide aggregate: a 6‐year follow‐up of a randomized controlled trial. Journal of Endodontics, 42, 533–537.
Kruse, C., Spin‐Neto, R., Reibel, J., Wenzel, A. & Kirkevang, L.L. (2017) Diagnostic validity of periapical radiography and CBCT for assessing periapical lesions that persist after endodontic surgery. Dento Maxillo Facial Radiology, 46, 20170210.
Kvist, T. & Reit, C. (1999) Results of endodontic retreatment: a randomized clinical study comparing surgical and nonsurgical procedures. Journal of Endodontics, 25, 814–817.
Liu, T.J., Zhou, J.N. & Guo, L.H. (2021) Impact of different regenerative techniques and materials on the healing outcome of endodontic surgery: a systematic review and meta‐analysis. International Endodontic Journal, 54, 536–555.
Molven, O., Halse, A. & Grung, B. (1987) Observer strategy and the radiographic classification of healing after endodontic surgery. International Journal of Oral and Maxillofacial Surgery, 16, 432–439.
Molven, O., Halse, A. & Grung, B. (1996) Incomplete healing (scar tissue) after periapical surgery—radiographic findings 8 to 12 years after treatment. Journal of Endodontics, 22, 264–268.
Nagendrababu, V., Duncan, H.F., Bjørndal, L., Kvist, T., Priya, E., Jayaraman, J. et al. (2020) PRIRATE 2020 guidelines for reporting randomized trials in endodontics: a consensus‐based development. International Endodontic Journal, 53, 764–773.
Ng, Y.L. & Gulabivala, K. (2023) Factors that influence the outcomes of surgical endodontic treatment. International Endodontic Journal, 56, 116–139.
Pallarés‐Serrano, A., Glera‐Suarez, P., Tarazona‐Alvarez, B., Peñarrocha‐Diago, M., Peñarrocha‐Diago, M. & Peñarrocha‐Oltra, D. (2021) Prognostic factors after endodontic microsurgery: a retrospective study of 111 cases with 5 to 9 years of follow‐up. Journal of Endodontics, 47, 397–403.
Pallarés‐Serrano, A., Glera‐Suarez, P., Tarazona‐Alvarez, B., Peñarrocha‐Oltra, D., Peñarrocha‐Diago, M. & Peñarrocha‐Diago, M. (2022) Healing of 295 endodontic microsurgery cases after long‐term (5‐9 years) versus middle‐term (1‐4 years) follow‐up. Journal of Endodontics, 48, 714–721.
Parmar, P.D., Dhamija, R., Tewari, S., Sangwan, P., Gupta, A., Duhan, J. et al. (2019) 2D and 3D radiographic outcome assessment of the effect of guided tissue regeneration using resorbable collagen membrane in the healing of through‐and‐through periapical lesions ‐ a randomized controlled trial. International Endodontic Journal, 52, 935–948.
Pecora, G., De Leonardis, D., Ibrahim, N., Bovi, M. & Cornelini, R. (2001) The use of calcium sulphate in the surgical treatment of a ‘through and through’ periradicular lesion. International Endodontic Journal, 34, 189–197.
Pecora, G., Kim, S., Celletti, R. & Davarpanah, M. (1995) The guided tissue regeneration principle in endodontic surgery: one‐year postoperative results of large periapical lesions. International Endodontic Journal, 28, 41–46.
Rosen, E., Salem, R., Kavalerchik, E., Kahn, A. & Tsesis, I. (2022) The effect of imaging modality on the evaluation of the outcome of endodontic surgery. Dento Maxillo Facial Radiology, 51, 20220164.
Rubinstein, R.A. & Kim, S. (2002) Long‐term follow‐up of cases considered healed one year after apical microsurgery. Journal of Endodontics, 28, 378–383.
Rud, J. & Andreasen, J.O. (1972) A study of failures after endodontic surgery by radiographic, histologic and stereomicroscopic methods. International Journal of Oral Surgery, 1, 311–328.
Safi, C., Kohli, M.R., Kratchman, S.I., Setzer, F.C. & Karabucak, B. (2019) Outcome of endodontic microsurgery using mineral trioxide aggregate or root repair material as root‐end filling material: a randomized controlled trial with cone‐beam computed tomographic evaluation. Journal of Endodontics, 45, 831–839.
Schloss, T., Sonntag, D., Kohli, M.R. & Setzer, F.C. (2017) A comparison of 2‐ and 3‐dimensional healing assessment after endodontic surgery using cone‐beam computed tomographic volumes or periapical radiographs. Journal of Endodontics, 43, 1072–1079.
Serrano‐Giménez, M., Sánchez‐Torres, A. & Gay‐Escoda, C. (2015) Prognostic factors on periapical surgery: a systematic review. Medicina Oral, Patologia Oral y Cirugia Bucal, 20, e715–e722.
Setzer, F.C., Kohli, M.R., Shah, S.B., Karabucak, B. & Kim, S. (2012) Outcome of endodontic surgery: a meta‐analysis of the literature—part 2: comparison of endodontic microsurgical techniques with and without the use of higher magnification. Journal of Endodontics, 38, 1–10.
Setzer, F.C., Shah, S.B., Kohli, M.R., Karabucak, B. & Kim, S. (2010) Outcome of endodontic surgery: a meta‐analysis of the literature—part 1: comparison of traditional root‐end surgery and endodontic microsurgery. Journal of Endodontics, 36, 1757–1765.
Skoglund, A. & Persson, G. (1985) A follow‐up study of apicoectomized teeth with total loss of the buccal bone plate. Oral Surgery, Oral Medicine, and Oral Pathology, 59, 78–81.
Song, M., Chung, W., Lee, S.J. & Kim, E. (2012) Long‐term outcome of the cases classified as successes based on short‐term follow‐up in endodontic microsurgery. Journal of Endodontics, 38, 1192–1196.
Song, M., Jung, I.Y., Lee, S.J., Lee, C.Y. & Kim, E. (2011) Prognostic factors for clinical outcomes in endodontic microsurgery: a retrospective study. Journal of Endodontics, 37, 927–933.
Song, M., Kim, S.G., Shin, S.J., Kim, H.C. & Kim, E. (2013) The influence of bone tissue deficiency on the outcome of endodontic microsurgery: a prospective study. Journal of Endodontics, 39, 1341–1345.
Song, M., Nam, T., Shin, S.J. & Kim, E. (2014) Comparison of clinical outcomes of endodontic microsurgery: 1 year versus long‐term follow‐up. Journal of Endodontics, 40, 490–494.
Tanomaru‐FIlho, M., Jorge, É.G., Guerreiro‐Tanomaru, J.M., Reis, J.M., Spin‐Neto, R. & Gonçalves, M. (2015) Two‐ and tridimensional analysis of periapical repair after endodontic surgery. Clinical Oral Investigations, 19, 17–25.
Taschieri, S., Corbella, S., Tsesis, I., Bortolin, M. & Del Fabbro, M. (2011) Effect of guided tissue regeneration on the outcome of surgical endodontic treatment of through‐and‐through lesions: a retrospective study at 4‐year follow‐up. Oral and Maxillofacial Surgery, 15, 153–159.
Taschieri, S., Del Fabbro, M., Testori, T., Saita, M. & Weinstein, R. (2008) Efficacy of guided tissue regeneration in the management of through‐and‐through lesions following surgical endodontics: a preliminary study. The International Journal of Periodontics & Restorative Dentistry, 28, 265–271.
Taschieri, S., Del Fabbro, M., Testori, T. & Weinstein, R. (2007) Efficacy of xenogeneic bone grafting with guided tissue regeneration in the management of bone defects after surgical endodontics. Journal of Oral and Maxillofacial Surgery, 65, 1121–1127.
Tawil, P.Z., Saraiya, V.M., Galicia, J.C. & Duggan, D.J. (2015) Periapical microsurgery: the effect of root dentinal defects on short‐ and long‐term outcome. Journal of Endodontics, 41, 22–27.
Tortorici, S., Difalco, P., Caradonna, L. & Tetè, S. (2014) Traditional endodontic surgery versus modern technique: a 5‐year controlled clinical trial. The Journal of Craniofacial Surgery, 25, 804–807.
Truschnegg, A., Rugani, P., Kirnbauer, B., Kqiku, L., Jakse, N. & Kirmeier, R. (2020) Long‐term follow‐up for apical microsurgery of teeth with core and post restorations. Journal of Endodontics, 46, 178–183.
Tsesis, I., Rosen, E., Schwartz‐Arad, D. & Fuss, Z. (2006) Retrospective evaluation of surgical endodontic treatment: traditional versus modern technique. Journal of Endodontics, 32, 412–416.
Tsesis, I., Rosen, E., Taschieri, S., Telishevsky Strauss, Y., Ceresoli, V. & Del Fabbro, M. (2013) Outcomes of surgical endodontic treatment performed by a modern technique: an updated meta‐analysis of the literature. Journal of Endodontics, 39, 332–339.
von Arx, T., Hänni, S. & Jensen, S.S. (2014) 5‐year results comparing mineral trioxide aggregate and adhesive resin composite for root‐end sealing in apical surgery. Journal of Endodontics, 40, 1077–1081.
von Arx, T., Janner, S.F., Hänni, S. & Bornstein, M.M. (2016a) Agreement between 2D and 3D radiographic outcome assessment one year after periapical surgery. International Endodontic Journal, 49, 915–925.
von Arx, T., Janner, S.F., Hänni, S. & Bornstein, M.M. (2016b) Evaluation of new cone‐beam computed tomographic criteria for radiographic healing evaluation after apical surgery: assessment of repeatability and reproducibility. Journal of Endodontics, 42, 236–242.
von Arx, T., Janner, S.F.M., Hänni, S. & Bornstein, M.M. (2019) Radiographic assessment of bone healing using cone‐beam computed tomographic scans 1 and 5 years after apical surgery. Journal of Endodontics, 45, 1307–1313.
von Arx, T., Jensen, S.S. & Hänni, S. (2007) Clinical and radiographic assessment of various predictors for healing outcome 1 year after periapical surgery. Journal of Endodontics, 33, 123–128.
von Arx, T., Jensen, S.S., Hänni, S. & Friedman, S. (2012) Five‐year longitudinal assessment of the prognosis of apical microsurgery. Journal of Endodontics, 38, 570–579.
von Arx, T., Jensen, S.S., Janner, S.F.M., Hänni, S. & Bornstein, M.M. (2019) A 10‐year follow‐up study of 119 teeth treated with apical surgery and root‐end filling with mineral trioxide aggregate. Journal of Endodontics, 45, 394–401.
von Arx, T., Peñarrocha, M. & Jensen, S. (2010) Prognostic factors in apical surgery with root‐end filling: a meta‐analysis. Journal of Endodontics, 36, 957–973.
Wang, Q., Cheung, G.S. & Ng, R.P. (2004) Survival of surgical endodontic treatment performed in a dental teaching hospital: a cohort study. International Endodontic Journal, 37, 764–775.
World Medical Association. (2013) World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA, 310, 2191–2194.
Yazdi, P.M., Schou, S., Jensen, S.S., Stoltze, K., Kenrad, B. & Sewerin, I. (2007) Dentine‐bonded resin composite (Retroplast) for root‐end filling: a prospective clinical and radiographic study with a mean follow‐up period of 8 years. International Endodontic Journal, 40, 493–503.
Yoo, Y.J., Kim, D.W., Perinpanayagam, H., Baek, S.H., Zhu, Q., Safavi, K. et al. (2020) Prognostic factors of long‐term outcomes in endodontic microsurgery: a retrospective cohort study over five years. Journal of Clinical Medicine, 9, 2210.
Zhou, W., Zheng, Q., Tan, X., Song, D., Zhang, L. & Huang, D. (2017) Comparison of mineral trioxide aggregate and iRoot BP plus root repair material as root‐end filling materials in endodontic microsurgery: a prospective randomized controlled study. Journal of Endodontics, 43, 1–6.