Histological evaluation of osseointegration between conventional and novel bone-level tapered implants in healed bone-A preclinical study.

animal model crestal bone formation histology histometry implant geometry osseointegration

Journal

Journal of periodontal research
ISSN: 1600-0765
Titre abrégé: J Periodontal Res
Pays: United States
ID NLM: 0055107

Informations de publication

Date de publication:
19 May 2024
Historique:
revised: 10 04 2024
received: 13 03 2024
accepted: 24 04 2024
medline: 20 5 2024
pubmed: 20 5 2024
entrez: 20 5 2024
Statut: aheadofprint

Résumé

To histologically compare osseointegration and crestal bone healing between newly introduced tapered, self-cutting bone-level test implants and tapered bone-level control implants in sites with fully healed sites. Sixty-six implants (33 test, 33 control) were placed 1 mm subcrestally in a minipig model and underwent qualitative histologic and quantitative histometric analyses after 3, 6 and 12 weeks of submerged healing. The primary and secondary outcomes were the bone-to-implant contact (BIC) and first bone-to-implant contact (fBIC). Outcomes between the test and control implants were statistically compared. The BIC values of the test implants were comparable and non-inferior over the time points studied, except for the 12 weeks time point which showed statistically significantly higher BIC values of the test (88.07 ± 5.35%) compared to the control implants (80.88 ± 7.51%) (p = .010). Similarly comparable and non-inferior were the fBIC values, except for the 6-week outcome, which showed statistically higher values for the test (-546.5 ± 450.80 μm) compared to the control implants (-75.7 ± 100.59 μm). fBIC results for the test implants were qualitatively more stable and consistent between test time points. Novel self-cutting bone-level test implants demonstrated superior osseointegration and similar bone levels compared to conventional bone-level implants after a healing period of 12 weeks in healed ridges.

Identifiants

pubmed: 38764144
doi: 10.1111/jre.13285
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Straumann AG

Informations de copyright

© 2024 The Authors. Journal of Periodontal Research published by John Wiley & Sons Ltd.

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Auteurs

Jean-Claude Imber (JC)

Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.

Andrea Roccuzzo (A)

Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.

Delia R Irani (DR)

Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.

Benjamin Bellón (B)

Department of Preclinical Research, Institut Straumann, Basel, Switzerland.
Faculty of Medicine and Health Technology, University of Tampere, Tampere, Finland.
Department of Periodontology, Faculty of Dentistry, University of Zurich, Zurich, Switzerland.

Dieter D Bosshardt (DD)

Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.

Anton Sculean (A)

Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.

Benjamin E Pippenger (BE)

Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.
Department of Preclinical Research, Institut Straumann, Basel, Switzerland.

Classifications MeSH