Steroid-Resistant Nephrotic Syndrome due to

NPHS2 gene glomerular disease hereditary nephrotic syndrome kidney transplantation posttransplant recurrence steroid-resistant nephrotic syndrome

Journal

Kidney international reports
ISSN: 2468-0249
Titre abrégé: Kidney Int Rep
Pays: United States
ID NLM: 101684752

Informations de publication

Date de publication:
Apr 2024
Historique:
received: 28 09 2023
revised: 07 12 2023
accepted: 02 01 2024
medline: 20 5 2024
pubmed: 20 5 2024
entrez: 20 5 2024
Statut: epublish

Résumé

Unlike idiopathic nephrotic syndrome (NS), hereditary podocytopathies are not expected to recur after kidney transplantation. However, some reports of posttransplant recurrence of NS in patients carrying variants in the Since January 2010, 61 patients identified at Necker-Enfants Malades Hospital and 56 enrolled in the PodoNet Registry with biallelic variants in the Of the 117 patients, 23 carried the p.Arg138Gln variant in the homozygous state and 16 in the compound heterozygous state. The other 78 patients carried different variants in the homozygous ( In this large cohort, the risk of patients with causative variants in the

Identifiants

DOI: 10.1016/j.ekir.2024.01.005 PMID: 38765578 PMC: PMC11101709
pubmed: 38765578
doi: 10.1016/j.ekir.2024.01.005
pii: S2468-0249(24)00005-6
pmc: PMC11101709
doi:

Types de publication

Journal Article

Langues

eng

Pagination

973-981

Investigateurs

Mounia Boutaba (M)
Dagmar Csaiscich (D)
Sergay Baiko (S)
Marta Azocar (M)
Lily Quiroz (L)
Lina Maria Serna Higuita (LM)
Jiří Dušek (J)
Bruno Ranchin (B)
Adriane Zaloszyc (A)
Tinatin Davitaia (T)
Jutta Gellermann (J)
Jun Oh (J)
Anette Melk (A)
Franz Schaefer (F)
Hagen Staude (H)
Nikoleta Printza (N)
Kalman Tory (K)
Alaleh Gheissari (A)
Giuseppe Remuzzi (G)
Andrea Pasini (A)
Gian Marco Ghiggeri (GM)
Gianluigi Ardissino (G)
Elisa Benetti (E)
Francesco Emma (F)
Roberta Camilla (R)
Nazym Nigmatullina (N)
Bilal Aoun (B)
Chebl Mourani (C)
Pauline Abou-Jaoudé (P)
Augustina Jankauskiene (A)
Anna Wasilewska (A)
Lidia Hyla Klekot (LH)
Aleksandra Zurowska (A)
Dorota Drozdz (D)
Marcin Tkaczyk (M)
Przemysław Sikora (P)
Danuta Ostalska (D)
Andrzej Brodkiewicz (A)
Mieczyslaw Litwin (M)
Małgorzata Panczyk-Tomaszewska (M)
Anna Medyńska (A)
Maria Szczepanska (M)
Alberto Caldas Afonso (AC)
Helena Jardim (H)
Adrian Lungu (A)
Alexej Tsygin (A)
Larisa Prikhodina (L)
Dusan Paripovic (D)
Radovan Bogdanovic (R)
Rafael T Krmar (RT)
Bassam Saeed (B)
Ali Anarat (A)
Ayse Balat (A)
Z Esra Baskin (ZE)
Nilgun Cakar (N)
Ozlem Erdogan (O)
Birsin Özcakar (B)
Fatih Ozaltin (F)
Onur Sakallioglu (O)
Oguz Soylemezoglu (O)
Sema Akman (S)
Faysal Gok (F)
Salim Caliskan (S)
Cengiz Candan (C)
Alev Yilmaz (A)
Betul Sozeri (B)
Ipek Akil (I)
Pelin Ertan (P)
Ozan Özkaya (O)
Mukaddes Kalyoncu (M)
Martin Bitzan (M)
Svitlana Formina (S)
Roman Sobko (R)

Informations de copyright

© 2024 International Society of Nephrology. Published by Elsevier Inc.

Auteurs

Jessica Kachmar (J)

Laboratoire des Maladies Rénales Héréditaires, Inserm UMR 1163, Imagine Institute for Genetic Diseases, Université Paris Cité, Paris, France.

Olivia Boyer (O)

Laboratoire des Maladies Rénales Héréditaires, Inserm UMR 1163, Imagine Institute for Genetic Diseases, Université Paris Cité, Paris, France.
Service de néphrologie pédiatrique Centre de Référence MARHEA, Hôpital Necker-Enfants Malades, Assistance publique, Hôpitaux de Paris (AP-HP), Paris, France.

Beata Lipska-Ziętkiewicz (B)

Centre for Rare Diseases and Clinical Genetics Unit, Medical University of Gdansk, Gdansk, Poland.

Vincent Morinière (V)

Service de Médecine Génomique des Maladies Rares, Hôpital Necker-Enfants Malades, Assistance publique, Hôpitaux de Paris (AP-HP), Paris, France.

Olivier Gribouval (O)

Laboratoire des Maladies Rénales Héréditaires, Inserm UMR 1163, Imagine Institute for Genetic Diseases, Université Paris Cité, Paris, France.

Laurence Heidet (L)

Laboratoire des Maladies Rénales Héréditaires, Inserm UMR 1163, Imagine Institute for Genetic Diseases, Université Paris Cité, Paris, France.
Service de néphrologie pédiatrique Centre de Référence MARHEA, Hôpital Necker-Enfants Malades, Assistance publique, Hôpitaux de Paris (AP-HP), Paris, France.

Irena Balasz-Chmielewska (I)

Department of Pediatrics, Nephrology and Hypertension, Medical University of Gdansk, Gdansk, Poland.

Elisa Benetti (E)

Pediatric Nephrology Unit, Padua University Hospital, Padua, Italy.

Sylvie Cloarec (S)

Service de Néphrologie-Hémodialyse pédiatrique, Centre de compétence Maladies Rénales Rares, CHRU Tours-Clocheville, Tours, France.

Dagmar Csaicsich (D)

Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.

Stéphane Decramer (S)

Pediatric Nephrology Unit, Toulouse University Hospital; Centre De Référence Des Maladies Rénales Rares du Sud-Ouest, SoRare; INSERM U1048, Institute of Cardiovascular and Metabolic Diseases, Toulouse, France.

Jutta Gellermann (J)

Klinik für Pädiatrie/Nephrologie, Charité Campus Virchox-Klinikum, Berlin, Germany.

Vincent Guigonis (V)

Pediatrics, Hôpital de la mère et de l'enfant, Limoges, France.

Julien Hogan (J)

Pediatric Nephrology, Hôpital Universitaire Robert-Debré; Paris Translational Research Center for Organ Transplantation, Inserm UMR-S970, Université Paris Cité, Paris, France.

Aysun Karabay Bayazit (AK)

Division of Pediatric Nephrology, Cukurova University, Adana, Türkiye.

Anette Melk (A)

Children's Hospital, Hannover Medical School, Hannover, Germany.

Nazym Nigmatullina (N)

National Research Center for Maternal and Child Heatlh, Astana, Kazakhstan.

Jun Oh (J)

Pediatric Nephrology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Fatih Ozaltin (F)

Department of Pediatric Nephrology, Hacettepe University, Faculty of Medicine, Sihhiye, Ankara, Türkiye.

Bruno Ranchin (B)

Pediatric Nephrology Unit, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, Université de Lyon, Lyon, France.

Michel Tsimaratos (M)

Faculté de médecine de Marseille, Université de la Méditerranée, Marseille, France.

Agnes Trautmann (A)

Department of Pediatric Nephrology, Center for Pediatric and Adolescent Medicine, University of Heidelberg, Germany.

Corinne Antignac (C)

Laboratoire des Maladies Rénales Héréditaires, Inserm UMR 1163, Imagine Institute for Genetic Diseases, Université Paris Cité, Paris, France.

Franz Schaefer (F)

Department of Pediatric Nephrology, Center for Pediatric and Adolescent Medicine, University of Heidelberg, Germany.

Guillaume Dorval (G)

Laboratoire des Maladies Rénales Héréditaires, Inserm UMR 1163, Imagine Institute for Genetic Diseases, Université Paris Cité, Paris, France.
Service de Médecine Génomique des Maladies Rares, Hôpital Necker-Enfants Malades, Assistance publique, Hôpitaux de Paris (AP-HP), Paris, France.

Classifications MeSH