Immunological and microbial shifts in the aging rhesus macaque lung during nontuberculous mycobacterial infection.

M. avium complex aging lung lung immunology microbiome rhesus macaque single-cell RNA sequencing

Journal

mBio
ISSN: 2150-7511
Titre abrégé: mBio
Pays: United States
ID NLM: 101519231

Informations de publication

Date de publication:
21 May 2024
Historique:
medline: 21 5 2024
pubmed: 21 5 2024
entrez: 21 5 2024
Statut: aheadofprint

Résumé

Nontuberculous mycobacteria (NTM) are environmentally ubiquitous organisms that predominately cause NTM pulmonary disease (NTMPD) in individuals over the age of 65. The incidence of NTMPD has increased in the U.S., exceeding that of Nontuberculous mycobacteria (NTM) are emerging as pathogens of high consequence, as cases of NTM pulmonary disease (NTMPD) have exceeded those of

Identifiants

DOI: 10.1128/mbio.00829-24 PMID: 38771046
pubmed: 38771046
doi: 10.1128/mbio.00829-24
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0082924

Auteurs

Isaac R Cinco (IR)

Department of Microbiology, Immunology, and Molecular Genetics, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.

Ethan G Napier (EG)

Department of Microbiology, Immunology, and Molecular Genetics, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.

Nicholas S Rhoades (NS)

Department of Microbiology, Immunology, and Molecular Genetics, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.

Michael H Davies (MH)

Division of Neuroscience, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.

Derek B Allison (DB)

Department of Pathology and Laboratory Medicine, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.

Steven G Kohama (SG)

Division of Neuroscience, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.

Luiz Bermudez (L)

Department of Microbiology, College of Sciences, Oregon State University, Corvallis, Oregon, USA.

Kevin Winthrop (K)

Division of Infectious Diseases, School of Medicine, Oregon Health and Science University, Portland, Oregon, USA.
Division of Infectious Diseases, School of Public Health, Oregon Health and Science University, Portland, Oregon, USA.

Cristina Fuss (C)

Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut, USA.

Eliot R Spindel (ER)

Division of Neuroscience, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.

Ilhem Messaoudi (I)

Department of Microbiology, Immunology, and Molecular Genetics, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.
ORCID: 0000-0003-3203-2405

Classifications MeSH