Interim 2023/2024 Season Influenza Vaccine Effectiveness in Primary and Secondary Care in the United Kingdom.


Journal

Influenza and other respiratory viruses
ISSN: 1750-2659
Titre abrégé: Influenza Other Respir Viruses
Pays: England
ID NLM: 101304007

Informations de publication

Date de publication:
May 2024
Historique:
revised: 12 03 2024
received: 28 02 2024
accepted: 13 03 2024
medline: 22 5 2024
pubmed: 22 5 2024
entrez: 22 5 2024
Statut: ppublish

Résumé

We report 2023/2024 season interim influenza vaccine effectiveness for three studies, namely, primary care in Great Britain, hospital settings in Scotland and hospital settings in England. A test negative design was used to estimate vaccine effectiveness. Estimated vaccine effectiveness against all influenzas ranged from 63% (95% confidence interval 46 to 75%) to 65% (41 to 79%) among children aged 2-17, from 36% (20 to 49%) to 55% (43 to 65%) among adults 18-64 and from 40% (29 to 50%) to 55% (32 to 70%) among adults aged 65 and over. During a period of co-circulation of influenza A(H1N1)pdm09 and A(H3N2) in the United Kingdom, evidence for effectiveness of the influenza vaccine in both children and adults was found.

Sections du résumé

BACKGROUND BACKGROUND
We report 2023/2024 season interim influenza vaccine effectiveness for three studies, namely, primary care in Great Britain, hospital settings in Scotland and hospital settings in England.
METHODS METHODS
A test negative design was used to estimate vaccine effectiveness.
RESULTS RESULTS
Estimated vaccine effectiveness against all influenzas ranged from 63% (95% confidence interval 46 to 75%) to 65% (41 to 79%) among children aged 2-17, from 36% (20 to 49%) to 55% (43 to 65%) among adults 18-64 and from 40% (29 to 50%) to 55% (32 to 70%) among adults aged 65 and over.
CONCLUSIONS CONCLUSIONS
During a period of co-circulation of influenza A(H1N1)pdm09 and A(H3N2) in the United Kingdom, evidence for effectiveness of the influenza vaccine in both children and adults was found.

Identifiants

pubmed: 38773753
doi: 10.1111/irv.13284
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e13284

Subventions

Organisme : UK Health Security Agency, Public Health Scotland and Public Health Wales

Informations de copyright

© 2024 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.

Références

UK Health Security Agency, “The Green Book; Chapter 19: Influenza. UKHSA Gateway Number 2020296,” accessed 15 Feb 2024, https://www.gov.uk/government/publications/influenza‐the‐green‐book‐chapter‐19.
G. Smith, A. McMahon, and A. Strath, “Seasonal Flu Immunisation Programme 2023/24: Confirmation of Adult Cohorts. 18 April 2023,” Letter, The Scottish Government, accessed February 15, 2024, https://www.sehd.scot.nhs.uk/cmo/CMO(2023)05.pdf.
World Health Organization (WHO), “Recommended Composition of Influenza Virus Vaccines for Use in the 2023–2024 Northern Hemisphere Influenza Season,” 24 February 2023, Meeting report, Geneva: WHO, accessed February 6, 2023, https://www.who.int/publications/m/item/recommended‐composition‐of‐influenza‐virus‐vaccines‐for‐use‐in‐the‐2023‐2024‐northern‐hemisphere‐influenza‐season.
Public Health Wales, “Public Health Wales Influenza Surveillance Report: Week 4 2024,” accessed February 6, 2024, https://phw.nhs.wales/topics/immunisation‐and‐vaccines/fluvaccine/weekly‐influenza‐and‐acute‐respiratory‐infection‐report/.
Public Health Scotland, “Viral Respiratory Diseases (Including Influenza and COVID‐19) in Scotland Surveillance Report: 01 February 2024,” accessed February 6, 2024, https://www.publichealthscotland.scot/publications/viral‐respiratory‐diseases‐including‐influenza‐and‐covid‐19‐in‐scotland‐surveillance‐report/viral‐respiratory‐diseases‐including‐influenza‐and‐covid‐19‐in‐scotland‐surveillance‐report‐1‐february‐2024/.
UK Health Security Agency, “National Influenza and COVID‐19 Surveillance Report. Week 5 Report (up to Week 4 2024 Data), 1 February 2024,” accessed February 6, 2024, https://www.gov.uk/government/statistics/national‐flu‐and‐covid‐19‐surveillance‐reports‐2023‐to‐2024‐season.
A. K. Clift, C. A. C. Coupland, R. H. Keogh, et al., “Living Risk Prediction Algorithm (QCOVID) for Risk of Hospital Admission and Mortality from Coronavirus 19 in Adults: National Derivation and Validation Cohort Study,” BMJ 371 (2020): m3731, https://doi.org/10.1136/bmj.m3731.
R. G. Pebody, H. Whitaker, J. Ellis, et al., “End of Season Influenza Vaccine Effectiveness in Primary Care in Adults and Children in the United Kingdom in 2018/19,” Vaccine 38, no. 3 (2020): 489–497, https://doi.org/10.1016/j.vaccine.2019.10.071.
H. Whitaker, K. Hassell, K. Hoschler, et al., “Influenza Vaccination During the 2021/22 Season: A Data‐Linkage Test‐Negative Case‐Control Study of Effectiveness Against Influenza Requiring Emergency Care in England and Serological Analysis of Primary Care Patients,” Vaccine 42 (2024): 1656–1664, https://doi.org/10.1016/j.vaccine.2024.02.006.
E. Kissling, M. Maurel, H. D. Emborg, et al., “Interim 2022/23 Influenza Vaccine Effectiveness: Six European Studies, October 2022 to January 2023,” Eurosurveillance 28, no. 21 (2023): pii=2300116, https://doi.org/10.2807/1560‐7917.ES.2023.28.21.2300116.
Public Health Scotland, “Community Acute Respiratory Infection (CARI) Surveillance in Primary Care,” 2023, https://publichealthscotland.scot/media/23330/cari‐surveillance‐in‐primary‐care‐english‐november2023.pdf.
M. K. Doll, S. M. Pettigrew, J. Ma, and A. Verma, “Effects of Confounding Bias in Coronavirus Disease 2019 (COVID‐19) and Influenza Vaccine Effectiveness Test‐Negative Designs Due to Correlated Influenza and COVID‐19 Vaccination Behaviors,” Clinical Infectious Diseases 75, no. 1 (2022): e564–e571, https://doi.org/10.1093/cid/ciac234.
C. Smolarchuk, C. Ickert, N. Zelyas, J. C. Kwong, and S. A. Buchan, “Early Influenza Vaccine Effectiveness Estimates Using Routinely Collected Data, Alberta, Canada, 2023/24 Season,” Eurosurveillance 29, no. 2 (2024): 2300709, https://doi.org/10.2807/1560‐7917.ES.2024.29.2.2300709.
World Health Organization (WHO), “Recommended Composition of Influenza Virus Vaccines for Use in the 2024 Southern Hemisphere Influenza Season,” 29 September 2023, Meeting report, Geneva: WHO, accessed February 15, 2023, https://www.who.int/publications/m/item/recommended‐composition‐of‐influenza‐virus‐vaccines‐for‐use‐in‐the‐2024‐southern‐hemisphere‐influenza‐season.

Auteurs

Heather Whitaker (H)

Statistics, Modelling and Economics Department, UK Health Security Agency, London, UK.

Beth Findlay (B)

Clinical and Protecting Health, Public Health Scotland, Glasgow, UK.

Jana Zitha (J)

Public Health Wales Communicable Disease Surveillance Centre and Vaccine Preventable Disease Programme, Public Health Wales NHS Trust, Cardiff, UK.

Rosalind Goudie (R)

Nuffield Department of Primary Care, University of Oxford, Oxford, UK.

Katie Hassell (K)

Immunisation and Vaccine Preventable Diseases Division, UK Health Security Agency, London, UK.

Josie Evans (J)

Clinical and Protecting Health, Public Health Scotland, Glasgow, UK.

Panoraia Kalapotharakou (P)

Public Health Wales Communicable Disease Surveillance Centre and Vaccine Preventable Disease Programme, Public Health Wales NHS Trust, Cardiff, UK.

Utkarsh Agrawal (U)

Nuffield Department of Primary Care, University of Oxford, Oxford, UK.

Beatrix Kele (B)

Respiratory Virus Unit, UK Health Security Agency, London, UK.

Mark Hamilton (M)

Clinical and Protecting Health, Public Health Scotland, Glasgow, UK.

Catherine Moore (C)

Wales Specialist Virology Centre, Public Health Wales Microbiology, Cardiff, UHW, Cardiff, UK.

Rachel Byford (R)

Nuffield Department of Primary Care, University of Oxford, Oxford, UK.

Julia Stowe (J)

Immunisation and Vaccine Preventable Diseases Division, UK Health Security Agency, London, UK.

Chris Robertson (C)

Clinical and Protecting Health, Public Health Scotland, Glasgow, UK.
Department of Mathematics and Statistics, University of Strathclyde, Glasgow, UK.

Anastasia Couzens (A)

Wales Specialist Virology Centre, Public Health Wales Microbiology, Cardiff, UHW, Cardiff, UK.

Gavin Jamie (G)

Nuffield Department of Primary Care, University of Oxford, Oxford, UK.

Katja Hoschler (K)

Respiratory Virus Unit, UK Health Security Agency, London, UK.

Kathleen Pheasant (K)

Wales Specialist Virology Centre, Public Health Wales Microbiology, Cardiff, UHW, Cardiff, UK.

Elizabeth Button (E)

Nuffield Department of Primary Care, University of Oxford, Oxford, UK.

Catherine Quinot (C)

Immunisation and Vaccine Preventable Diseases Division, UK Health Security Agency, London, UK.

Tim Jones (T)

Wales Specialist Virology Centre, Public Health Wales Microbiology, Cardiff, UHW, Cardiff, UK.

Sneha Anand (S)

Nuffield Department of Primary Care, University of Oxford, Oxford, UK.

Conall Watson (C)

Immunisation and Vaccine Preventable Diseases Division, UK Health Security Agency, London, UK.

Nick Andrews (N)

Immunisation and Vaccine Preventable Diseases Division, UK Health Security Agency, London, UK.

Simon de Lusignan (S)

Nuffield Department of Primary Care, University of Oxford, Oxford, UK.
Research and Surveillance Centre, Royal College of General Practitioners, London, UK.

Maria Zambon (M)

Respiratory Virus Unit, UK Health Security Agency, London, UK.

Christopher Williams (C)

Public Health Wales Communicable Disease Surveillance Centre, Public Health Wales NHS Trust, Cardiff, UK.

Simon Cottrell (S)

Public Health Wales Communicable Disease Surveillance Centre and Vaccine Preventable Disease Programme, Public Health Wales NHS Trust, Cardiff, UK.

Kimberly Marsh (K)

Clinical and Protecting Health, Public Health Scotland, Glasgow, UK.

Jim McMenamin (J)

Clinical and Protecting Health, Public Health Scotland, Glasgow, UK.

Jamie Lopez Bernal (J)

Immunisation and Vaccine Preventable Diseases Division, UK Health Security Agency, London, UK.

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