Assessment of fluence- and dose-averaged linear energy transfer with passive luminescence detectors in clinical proton beams.

FNTD LET Linear energy transfer Luminescence detectors OSLD TLD

Journal

Physics in medicine and biology
ISSN: 1361-6560
Titre abrégé: Phys Med Biol
Pays: England
ID NLM: 0401220

Informations de publication

Date de publication:
21 May 2024
Historique:
medline: 22 5 2024
pubmed: 22 5 2024
entrez: 22 5 2024
Statut: aheadofprint

Résumé

This work investigates the use of passive luminescence detectors to determine different types of averaged linear energy transfer (\overline{LET}) for the energies relevant to proton therapy. The experimental results are compared to reference values obtained from Monte Carlo simulations. Optically stimulated luminescence detectors (OSLDs), fluorescent nuclear track detectors (FNTDs), and two different groups of thermoluminescence detectors (TLDs) were irradiated at four different radiation qualities. For each irradiation, the fluence- (\overline{LET} All types of \overline{LET} could be assessed with the detectors. The experimental determination of \overline{LET} OSLDs, TLDs, and FNTDs can be used to determine \overline{LET} and RBE in proton therapy. With the capability to determine dose through ionization quenching corrections derived from \overline{LET}, OSLDs and TLDs can simultaneously ascertain dose, \overline{LET}, and RBE. This makes passive detectors appealing for measurements in phantoms, facilitating the validation of clinical treatment plans or experiments related to proton therapy.

Identifiants

pubmed: 38774985
doi: 10.1088/1361-6560/ad4e8e
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Creative Commons Attribution license.

Auteurs

Iván Domingo Muñoz (ID)

Heidelberg Institute for Radiation Oncology (HIRO), National Center for Radiation Research in Oncology, Im Neuenheimer Feld 280, Heidelberg, Heidelberg, 69120, GERMANY.

Olivier Van Hoey (O)

Radiation protection Dosimetry and Calibration Expert Group, Belgian Nuclear Research Centre (SCK•CEN) , Boeretang 200, Mol, 2400, BELGIUM.

Alessio Parisi (A)

Radiation Oncology, Mayo Clinic, 4500 San Pablo Rd S, Jacksonville, Florida, 32224, UNITED STATES.

Niels Bassler (N)

Department of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 99, Aarhus N, 8250, DENMARK.

Leszek Grzanka (L)

Institute of Nuclear Physics, Polish Academy of Sciences (IFJ PAN), ul. Radzikowskiego 152, Kraków, 31-342, POLAND.

Marijke De Saint-Hubert (M)

Radiation protection Dosimetry and Calibration Expert Group, Belgian Nuclear Research Centre (SCK•CEN), Boeretang 200, Mol, 2400, BELGIUM.

Ana Vaniqui (A)

Radiation protection Dosimetry and Calibration Expert Group, Belgian Nuclear Research Centre (SCK•CEN), Boeretang 200, Mol, 2400, BELGIUM.

Pawel Olko (P)

PAN, Polish Academy of Sciences, ul Radzikowskiego 152, Krakow, Kraków, 31-342, POLAND.

Michał Sądel (M)

Institute of Nuclear Physics, Polish Academy of Sciences (IFJ PAN), ul. Radzikowskiego 152, Kraków, 31-342, POLAND.

Liliana Stolarczyk (L)

Dansk Center for Partikelterapi, Aarhus University Hospital Skejby, Palle Juul-Jensens Boulevard 25, Aarhus, 8200, DENMARK.

Anne Vestergaard (A)

Danish Center for Particle Therapy, Aarhus University, Palle Juul-Jensens Blvd. 25, Aarhus, 8200, DENMARK.

Oliver Jaekel (O)

Division for Medical Physics in Radiotherapy (E040), Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120 Heidelberg, Heidelberg, 69120, GERMANY.

Eduardo G Yukihara (EG)

Department of Radiation Safety and Security, Paul Scherrer Institut PSI, Forschungsstrasse 111, OFLD/006, Villigen, Aargau, 5232, SWITZERLAND.

Jeppe Brage Christensen (JB)

Department of Radiation Safety and Security, Paul Scherrer Institut PSI, Forschungsstrasse 111, Villigen, Aargau, 5232, SWITZERLAND.

Classifications MeSH