The state of health in the European Union (EU-27) in 2019: a systematic analysis for the Global Burden of Disease study 2019.
European Burden of Disease Network
European Union
Global Burden of Diseases
Health status
Population health
Journal
BMC public health
ISSN: 1471-2458
Titre abrégé: BMC Public Health
Pays: England
ID NLM: 100968562
Informations de publication
Date de publication:
22 May 2024
22 May 2024
Historique:
received:
31
05
2023
accepted:
05
04
2024
medline:
23
5
2024
pubmed:
23
5
2024
entrez:
22
5
2024
Statut:
epublish
Résumé
The European Union (EU) faces many health-related challenges. Burden of diseases information and the resulting trends over time are essential for health planning. This paper reports estimates of disease burden in the EU and individual 27 EU countries in 2019, and compares them with those in 2010. We used the Global Burden of Disease 2019 study estimates and 95% uncertainty intervals for the whole EU and each country to evaluate age-standardised death, years of life lost (YLLs), years lived with disability (YLDs) and disability-adjusted life years (DALYs) rates for Level 2 causes, as well as life expectancy and healthy life expectancy (HALE). In 2019, the age-standardised death and DALY rates in the EU were 465.8 deaths and 20,251.0 DALYs per 100,000 inhabitants, respectively. Between 2010 and 2019, there were significant decreases in age-standardised death and YLL rates across EU countries. However, YLD rates remained mainly unchanged. The largest decreases in age-standardised DALY rates were observed for "HIV/AIDS and sexually transmitted diseases" and "transport injuries" (each -19%). "Diabetes and kidney diseases" showed a significant increase for age-standardised DALY rates across the EU (3.5%). In addition, "mental disorders" showed an increasing age-standardised YLL rate (14.5%). There was a clear trend towards improvement in the overall health status of the EU but with differences between countries. EU health policymakers need to address the burden of diseases, paying specific attention to causes such as mental disorders. There are many opportunities for mutual learning among otherwise similar countries with different patterns of disease.
Sections du résumé
BACKGROUND
BACKGROUND
The European Union (EU) faces many health-related challenges. Burden of diseases information and the resulting trends over time are essential for health planning. This paper reports estimates of disease burden in the EU and individual 27 EU countries in 2019, and compares them with those in 2010.
METHODS
METHODS
We used the Global Burden of Disease 2019 study estimates and 95% uncertainty intervals for the whole EU and each country to evaluate age-standardised death, years of life lost (YLLs), years lived with disability (YLDs) and disability-adjusted life years (DALYs) rates for Level 2 causes, as well as life expectancy and healthy life expectancy (HALE).
RESULTS
RESULTS
In 2019, the age-standardised death and DALY rates in the EU were 465.8 deaths and 20,251.0 DALYs per 100,000 inhabitants, respectively. Between 2010 and 2019, there were significant decreases in age-standardised death and YLL rates across EU countries. However, YLD rates remained mainly unchanged. The largest decreases in age-standardised DALY rates were observed for "HIV/AIDS and sexually transmitted diseases" and "transport injuries" (each -19%). "Diabetes and kidney diseases" showed a significant increase for age-standardised DALY rates across the EU (3.5%). In addition, "mental disorders" showed an increasing age-standardised YLL rate (14.5%).
CONCLUSIONS
CONCLUSIONS
There was a clear trend towards improvement in the overall health status of the EU but with differences between countries. EU health policymakers need to address the burden of diseases, paying specific attention to causes such as mental disorders. There are many opportunities for mutual learning among otherwise similar countries with different patterns of disease.
Identifiants
pubmed: 38778362
doi: 10.1186/s12889-024-18529-3
pii: 10.1186/s12889-024-18529-3
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1374Investigateurs
Cristiana Abbafati
(C)
Hassan Abolhassani
(H)
Victor Adekanmbi
(V)
Keivan Ahmadi
(K)
Sepideh Ahmadi
(S)
Adel Al-Jumaily
(A)
François Alla
(F)
Jordi Alonso
(J)
Robert Ancuceanu
(R)
Catalina Liliana Andrei
(CL)
Tudorel Andrei
(T)
Sofia Androudi
(S)
Josep M Antó
(JM)
Seth Christopher Yaw Appiah
(SCY)
Olatunde Aremu
(O)
Benedetta Armocida
(B)
Johan Ärnlöv
(J)
Ashokan Arumugam
(A)
Sameh Attia
(S)
Avinash Aujayeb
(A)
Marcel Ausloos
(M)
Jose L Ayuso-Mateos
(JL)
Maciej Banach
(M)
Till Winfried Bärnighausen
(TW)
Francesco Barone-Adesi
(F)
Sandra Barteit
(S)
Sanjay Basu
(S)
Bernhard T Baune
(BT)
Massimiliano Beghi
(M)
Luis Belo
(L)
Derrick A Bennett
(DA)
Antonio Biondi
(A)
Mahdi Bohluli
(M)
Israel Júnior Borges do Nascimento
(IJB)
Nicola Luigi Bragazzi
(NL)
Tasanee Braithwaite
(T)
Hermann Brenner
(H)
Danilo Buonsenso
(D)
Reinhard Busse
(R)
Daniela Calina
(D)
Giulia Carreras
(G)
Márcia Carvalho
(M)
Giulio Castelpietra
(G)
Alberico L Catapano
(AL)
Maria Sofia Cattaruzza
(MS)
Joht Singh Chandan
(JS)
Periklis Charalampous
(P)
Vijay Kumar Chattu
(VK)
Simiao Chen
(S)
Rajiv Chowdhury
(R)
Hanne Christensen
(H)
Sheng-Chia Chung
(SC)
Joao Conde
(J)
Barbara Corso
(B)
Natália Cruz-Martins
(N)
Giovanni Damiani
(G)
Alejandro de la Torre-Luque
(A)
Andreas K Demetriades
(AK)
Nikolaos Dervenis
(N)
Mostafa Dianatinasab
(M)
Diana Dias da Silva
(DD)
Abdel Douiri
(A)
David Edvardsson
(D)
Luchuo Engelbert Bain
(LE)
Francesco Esposito
(F)
Adeniyi Francis Fagbamigbe
(AF)
Carla Sofia eSá Farinha
(CSE)
Seyed-Mohammad Fereshtehnejad
(SM)
João C Fernandes
(JC)
Pietro Ferrara
(P)
Peter Andras Gaal
(PA)
Silvano Gallus
(S)
Lucia Galluzzo
(L)
Mariana Gaspar Fonseca
(MG)
Gus Gazzard
(G)
Alessandro Gialluisi
(A)
Simona Giampaoli
(S)
Paramjit Singh Gill
(PS)
James C Glasbey
(JC)
Giuseppe Gorini
(G)
Michal Grivna
(M)
Abdul Hafiz
(A)
Josep Maria Haro
(JM)
Jan Hartvigsen
(J)
Simon I Hay
(SI)
Behzad Heibati
(B)
David Hillus
(D)
Mehdi Hosseinzadeh
(M)
Mihaela Hostiuc
(M)
Sorin Hostiuc
(S)
Salman Hussain
(S)
Gaetano Isola
(G)
Olatunji Johnson
(O)
Jost B Jonas
(JB)
Tamas Joo
(T)
Jacek Jerzy Jozwiak
(JJ)
Mikk Jürisson
(M)
Marina Karanikolos
(M)
Joonas H Kauppila
(JH)
Moien A B Khan
(MAB)
Khaled Khatab
(K)
Miloslav Klugar
(M)
Ai Koyanagi
(A)
Om P Kurmi
(OP)
Dian Kusuma
(D)
Carlo La Vecchia
(C)
Ben Lacey
(B)
Demetris Lamnisos
(D)
Heidi Jane Larson
(HJ)
Anders O Larsson
(AO)
Savita Lasrado
(S)
Paolo Lauriola
(P)
Jeffrey V Lazarus
(JV)
Caterina Ledda
(C)
Paul H Lee
(PH)
Mall Leinsalu
(M)
Matilde Leonardi
(M)
Miriam Levi
(M)
An Li
(A)
Christine Linehan
(C)
Giancarlo Logroscino
(G)
Stefan Lorkowski
(S)
Joana A Loureiro
(JA)
Ronan A Lyons
(RA)
Áurea M Madureira-Carvalho
(ÁM)
Azeem Majeed
(A)
Alexander G Mathioudakis
(AG)
Colm McAlinden
(C)
John J McGrath
(JJ)
Ritesh G Menezes
(RG)
Alexios-Fotios A Mentis
(AA)
Atte Meretoja
(A)
Tuomo J Meretoja
(TJ)
Tomislav Mestrovic
(T)
Junmei Miao Jonasson
(JM)
Bartosz Miazgowski
(B)
Tomasz Miazgowski
(T)
Andreea Mirica
(A)
Shafiu Mohammed
(S)
Ali H Mokdad
(AH)
Ute Mons
(U)
Joana Morgado-da-Costa
(J)
Francesk Mulita
(F)
Christopher J L Murray
(CJL)
Ionut Negoi
(I)
Ruxandra Irina Negoi
(RI)
Serban Mircea Negru
(SM)
Evangelia Nena
(E)
Nurulamin M Noor
(NM)
George Ntaios
(G)
Bogdan Oancea
(B)
Frank B Osei
(FB)
Adrian Otoiu
(A)
Raffaele Palladino
(R)
Songhomitra Panda-Jonas
(S)
Shahina Pardhan
(S)
Jay Patel
(J)
Mihaela Paun
(M)
Paolo Pedersini
(P)
Umberto Pensato
(U)
Renato B Pereira
(RB)
Jorge Pérez-Gómez
(J)
Norberto Perico
(N)
Ionela-Roxana Petcu
(IR)
Carrie B Peterson
(CB)
Marina Pinheiro
(M)
Maarten J Postma
(MJ)
Alberto Raggi
(A)
Amir Masoud Rahmani
(AM)
Chythra R Rao
(CR)
Salman Rawaf
(S)
Reza Rawassizadeh
(R)
Giuseppe Remuzzi
(G)
Abanoub Riad
(A)
Simona Sacco
(S)
Mohammad Reza Saeb
(MR)
Brijesh Sathian
(B)
Davide Sattin
(D)
Nikolaos Scarmeas
(N)
Falk Schwendicke
(F)
Rahman Shiri
(R)
Velizar Shivarov
(V)
Kibrom T Sibhatu
(KT)
Biagio Simonetti
(B)
Søren T Skou
(ST)
Joan B Soriano
(JB)
Ireneous N Soyiri
(IN)
Nicholas Steel
(N)
Simona Cătălina Stefan
(SC)
Fridolin Steinbeis
(F)
Paschalis Steiropoulos
(P)
Leo Stockfelt
(L)
Saverio Stranges
(S)
Johan Sundström
(J)
Rafael Tabarés-Seisdedos
(R)
Arulmani Thiyagarajan
(A)
Roman Topor-Madry
(R)
Marcos Roberto Tovani-Palone
(MR)
Nikolaos Tsilimparis
(N)
Brigid Unim
(B)
Marco Vacante
(M)
Jef Van den Eynde
(J)
Tommi Juhani Vasankari
(TJ)
Massimiliano Veroux
(M)
Jorge Hugo Villafañe
(JH)
Francesco S Violante
(FS)
Yanzhong Wang
(Y)
Ronny Westerman
(R)
Charles D A Wolfe
(CDA)
Grant M A Wyper
(GMA)
Sanni Yaya
(S)
Vesna Zadnik
(V)
Jean-David Zeitoun
(JD)
Alimuddin Zumla
(A)
Informations de copyright
© 2024. The Author(s).
Références
Nicole Scholz, Members’ Research Service. Addressing health inequalities in the European Union, Concepts, action, state of play. Eur Parliamentary Res Serv. 2020. https://doi.org/10.2861/567478 .
Jutz R. Health inequalities in Europe: Does minimum income protection make a difference? Curr Sociol. 2021;69:99–118.
doi: 10.1177/0011392119890657
Costantini AS, Seniori Costantini A, Gallo F, et al. Population health and status of epidemiology in Western European, Balkan and Baltic countries. Int J Epidemiol. 2015;44:300–23.
doi: 10.1093/ije/dyu256
Health at a glance: Europe 2020: State of health in the EU cycle. URL https://www.oecd-ilibrary.org/social-issues-migration-health/health-at-a-glance-europe-2020_82129230-en . Accessed 30 Apr 2021.
European Commission. The health status of the European Union narrowing the health gap. Luxembourg: Office for Official Publications of the European Communities; 2003. https://openlibrary.org/books/OL16254528M/The_health_status_of_the_European_Union .
Nuyts PAW, Hewer RMF, Kuipers MAG, et al. Youth Access to Cigarettes Across Seven European Countries: A Mixed-Methods Study. Nicotine Tob Res. 2020;22:1989–96.
doi: 10.1093/ntr/ntz180
pubmed: 31535686
Garin N, Koyanagi A, Chatterji S, et al. Global Multimorbidity Patterns: A Cross-Sectional, Population-Based, Multi-Country Study. J Gerontol A Biol Sci Med Sci. 2016;71:205–14.
doi: 10.1093/gerona/glv128
pubmed: 26419978
O’Caoimh R, Galluzzo L, Rodríguez-Laso Á, et al. Prevalence of frailty at population level in European ADVANTAGE Joint Action Member States: a systematic review and meta-analysis. Ann Ist Super Sanita. 2018;54:226–38.
pubmed: 30284550
Colombo F, García-Goñi M, Schwierz C. Addressing multimorbidity to improve healthcare and economic sustainability. J Comorb. 2016;6:21–7.
doi: 10.15256/joc.2016.6.74
pubmed: 29090168
pmcid: 5556464
Quality of life indicators - health. URL https://ec.europa.eu/eurostat/statistics-explained/index.php?title=Quality_of_life_indicators_-_health&oldid=566497 Accessed 5 July 2022.
Santos JV, Lobo M, Neiva RM, et al. European Union state of health from 1990 to 2017: time trends and its enlargements’ effects. Int J Public Health. 2020;65:175–86.
doi: 10.1007/s00038-020-01335-0
pubmed: 32067062
Boncz I, Vajda R, Ágoston I, Endrei D, Sebestyén A. Changes in the health status of the population of Central and Eastern European countries between 1990 and 2010. Eur J Health Econ. 2014;15(Suppl 1):S137–41.
doi: 10.1007/s10198-014-0602-8
pubmed: 24832844
Santos JV, Souza J, Valente J, et al. The state of health in the European Union (EU-28) in 2017: an analysis of the burden of diseases and injuries. Eur J Public Health. 2020;30:573–8.
doi: 10.1093/eurpub/ckz203
pubmed: 31821479
GBD 2019 Demographics Collaborators. Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019. Lancet. 2020;396:1160–203.
doi: 10.1016/S0140-6736(20)30977-6
Vos T, Lim SS, Abbafati C, et al. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020;396:1204–22.
doi: 10.1016/S0140-6736(20)30925-9
GBD 2019 Risk Factors Collaborators. Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020;396:1223–49.
doi: 10.1016/S0140-6736(20)30752-2
GBD 2019 Viewpoint Collaborators. Five insights from the Global Burden of Disease Study 2019. Lancet. 2020;396:1135–59.
doi: 10.1016/S0140-6736(20)31404-5
Foreman KJ, Lozano R, Lopez AD, Murray CJ. Modeling causes of death: an integrated approach using CODEm. Popul Health Metr. 2012;10:1.
doi: 10.1186/1478-7954-10-1
pubmed: 22226226
pmcid: 3315398
Martinez R, Soliz P, Caixeta R, Ordunez P. Reflection on modern methods: years of life lost due to premature mortality—a versatile and comprehensive measure for monitoring non-communicable disease mortality. Int J Epidemiol. 2019;48:1367–76.
doi: 10.1093/ije/dyy254
pubmed: 30629192
pmcid: 6693813
Global Health Data Exchange (GHDx). 2014.URL http://www.healthdata.org/about/ghdx . Accessed 30 Apr 2021.
GBD Compare. 2014.URL http://www.healthdata.org/data-visualization/gbd-compare . Accessed 30 Apr 2021.
R Core Team. R: A language and environment for statistical computing. Vienna: R Foundation for Statistical Computing; 2021. https://www.R-project.org/ .
Stevens GA, Alkema L, Black RE, et al. Guidelines for Accurate and Transparent Health Estimates Reporting: the GATHER statement. Lancet. 2016;388:e19-23.
doi: 10.1016/S0140-6736(16)30388-9
pubmed: 27371184
Vandenberghe D, Albrecht J. The financial burden of non-communicable diseases in the European Union: a systematic review. Eur J Public Health. 2020;30:833–9.
doi: 10.1093/eurpub/ckz073
pubmed: 31220862
Wang Y, Wang J. Modelling and prediction of global non-communicable diseases. BMC Public Health. 2020;20:822.
doi: 10.1186/s12889-020-08890-4
pubmed: 32487173
pmcid: 7268487
Iburg KM, Charalampous P, Allebeck P, et al. Burden of disease among older adults in Europe-trends in mortality and disability, 1990–2019. Eur J Public Health. 2023;33(1):121–6.
doi: 10.1093/eurpub/ckac160
pubmed: 36421036
Yang X, Chen H, Sang S, Chen H, Li L, Yang X, Burden of All Cancers Along With Attributable Risk Factors in China From,. to 2019: Comparison With Japan, European Union, and USA. Front Public Health. 1990;2022:10. https://doi.org/10.3389/fpubh.2022.862165 .
doi: 10.3389/fpubh.2022.862165
Dyba T, Randi G, Bray F, Martos C, Giusti F, Nicholson N, Gavin A, Flego M, Neamtiu L, Dimitrova N, Negrão Carvalho R, Ferlay J, Bettio M. The European cancer burden in 2020: Incidence and mortality estimates for 40 countries and 25 major cancers. Eur J Cancer. 2021;157:308–47.
doi: 10.1016/j.ejca.2021.07.039
pubmed: 34560371
pmcid: 8568058
Bozhar H, McKee M, Spadea T, Veerus P, Heinävaara S, Anttila A, Senore C, Zielonke N, van Ravesteyn NT, Lansdorp-Vogelaar I, de Koning HJ, Heijnsdijk EAM. EU-TOPIA consortium. Socio-economic inequality of utilization of cancer testing in Europe: A cross-sectional study. Prev Med Rep. 2022;26:101733.
doi: 10.1016/j.pmedr.2022.101733
pubmed: 35198362
pmcid: 8850331
Sørensen HT, Bredahl Kristensen FP. Cardiovascular diseases and health inequalities in Europe-a pressing public health challenge. Lancet Reg Health Eur. 2023;4(33):100722.
doi: 10.1016/j.lanepe.2023.100722
Castelpietra G, Knudsen AKS, Agardh EE, et al. The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990–2019: Findings from the Global Burden of Disease Study 2019. Lancet Reg Health Eur. 2022;1(16):100341.
doi: 10.1016/j.lanepe.2022.100341
Stumbrys D, Jasilionis D, Pūras D. The burden of mental health-related mortality in the Baltic States in 2007–2018. BMC Public Health. 2022;22(1):1776.
doi: 10.1186/s12889-022-14175-9
pubmed: 36123665
pmcid: 9487037
van de Laar MJ, Likatavicius G. HIV and AIDS in the European Union, 2008. Euro Surveill. 2009;14(47):19422.
pubmed: 19941809
GBD 2017 HIV collaborators. Global, regional, and national incidence, prevalence, and mortality of HIV, 1980–2017, and forecasts to 2030, for 195 countries and territories: a systematic analysis for the Global Burden of Diseases, Injuries, and Risk Factors Study 2017. Lancet HIV. 2019;6:e831-59.
doi: 10.1016/S2352-3018(19)30196-1
Taquet M, Geddes JR, Husain M, Luciano S, Harrison PJ. 6-month neurological and psychiatric outcomes in 236 379 survivors of COVID-19: a retrospective cohort study using electronic health records. Lancet Psychiatry. 2021;8:416–27.
doi: 10.1016/S2215-0366(21)00084-5
pubmed: 33836148
pmcid: 8023694
COVID-19 Mental Disorders Collaborators. Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic. Lancet. 2021;398:1700–12.
doi: 10.1016/S0140-6736(21)02143-7
Launch of new WHO Mental Health Report: Transforming mental health for all. https://www.who.int/news-room/events/detail/2022/06/17/default-calendar/launch-of-new-who-mental-health-report--transforming-mental-health-for-all . Accessed 2 Jun 2022.
Wyper GMA, Grant I, Fletcher E, Chalmers N, McCartney G, Stockton DL. Prioritising the development of severity distributions in burden of disease studies for countries in the European region. Arch Public Health. 2020;78:3.
doi: 10.1186/s13690-019-0385-6
pubmed: 31921418
pmcid: 6950931
Fahy N, Hervey T, Greer S, et al. How will Brexit affect health services in the UK? An updated evaluation. Lancet. 2019;393:949–58.
doi: 10.1016/S0140-6736(19)30425-8
pubmed: 30819519
Wyper GMA, Grant I, Fletcher E, McCartney G, Fischbacher C, Stockton DL. How do world and European standard populations impact burden of disease studies? A case study of disability-adjusted life years (DALYs) in Scotland. Arch Public Health. 2020;78:1.
doi: 10.1186/s13690-019-0383-8
pubmed: 31908777
pmcid: 6941317
Park J-H, Eum J-H, Bold B, Cheong H-K. Burden of disease due to dementia in the elderly population of Korea: present and future. BMC Public Health. 2013;13:293.
doi: 10.1186/1471-2458-13-293
pubmed: 23552095
pmcid: 3626581