A case series of non-small cell lung cancer patients with

Germline pathogenic mutations in We report three cases of patients affected by Li Fraumeni syndrome who developed non-small cell lung cancer with Young patients affected by oncogene-addicted non-small cell lung cancer and with a positive familial cancer history should be referred for an accurate genetic counselling to look for Li Fraumeni syndrome. The underlying molecular connection between

Déclaration de conflit d'intérêts

Declaration of conflicting interestThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: M.T. received speakers’ and consultants’ fee from Astra-Zeneca, Pfizer, Eli-Lilly, BMS, Novartis, Roche, MSD, Boehringer Ingelheim, Otsuka, Takeda, Pierre Fabre, Amgen, Merck, Sanofi. M.T. received institutional research grants from Astra-Zeneca, Boehringer Ingelheim.F. G. received honoraria or personal fees for the advisory role or consulting from Eli Lilly, Novartis, AstraZeneca, and Bristol-Myers Squibb outside the submitted work.The other authors declare that there is no conflict of interest.