Reversible male contraception by targeted inhibition of serine/threonine kinase 33.

Male Animals Mice Contraceptive Agents, Male / pharmacology Protein Serine-Threonine Kinases / antagonists & inhibitors Humans Protein Kinase Inhibitors / pharmacology Testis / drug effects Blood-Testis Barrier / drug effects Small Molecule Libraries / chemistry

Journal

Science (New York, N.Y.)
ISSN: 1095-9203
Titre abrégé: Science
Pays: United States
ID NLM: 0404511

Informations de publication

Date de publication:
24 May 2024
Historique:
medline: 23 5 2024
pubmed: 23 5 2024
entrez: 23 5 2024
Statut: ppublish

Résumé

Men or mice with homozygous serine/threonine kinase 33 (

Identifiants

DOI: 10.1126/science.adl2688 PMID: 38781365
pubmed: 38781365
doi: 10.1126/science.adl2688
doi:

Substances chimiques

Contraceptive Agents, Male 0
Protein Serine-Threonine Kinases EC 2.7.11.1
Protein Kinase Inhibitors 0
Small Molecule Libraries 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

885-890

Commentaires et corrections

Type : CommentIn

Auteurs

Angela F Ku (AF)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
ORCID: 0000-0003-1768-9345

Kiran L Sharma (KL)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
ORCID: 0000-0002-1988-389X

Hai Minh Ta (HM)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX 77030, USA.
ORCID: 0000-0002-7298-6177

Courtney M Sutton (CM)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
ORCID: 0000-0001-9994-990X

Kurt M Bohren (KM)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
ORCID: 0000-0002-3183-4118

Yong Wang (Y)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.

Srinivas Chamakuri (S)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
ORCID: 0000-0002-7586-4992

Ruihong Chen (R)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.

John M Hakenjos (JM)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
ORCID: 0009-0008-4047-6923

Ravikumar Jimmidi (R)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
ORCID: 0000-0003-3819-0092

Katarzyna Kent (K)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
ORCID: 0000-0002-4528-3425

Feng Li (F)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX 77030, USA.
ORCID: 0000-0002-9680-4614

Jian-Yuan Li (JY)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
ORCID: 0000-0003-4733-1010

Lang Ma (L)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.

Chandrashekhar Madasu (C)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
ORCID: 0000-0002-2152-9689

Murugesan Palaniappan (M)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
ORCID: 0000-0003-4916-6565

Stephen S Palmer (SS)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.

Xuan Qin (X)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
ORCID: 0000-0003-3728-5911

Matthew B Robers (MB)

Promega Corporation, Madison, WI 53711, USA.

Banumathi Sankaran (B)

Molecular Biophysics and Integrated Bioimaging, Berkeley Center for Structural Biology, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
ORCID: 0000-0002-3266-8131

Zhi Tan (Z)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX 77030, USA.

Yasmin M Vasquez (YM)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
ORCID: 0000-0003-4255-9761

Jian Wang (J)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
ORCID: 0009-0000-9178-1225

Jennifer Wilkinson (J)

Promega Corporation, Madison, WI 53711, USA.
ORCID: 0009-0002-1994-715X

Zhifeng Yu (Z)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
ORCID: 0000-0002-3130-6438

Qiuji Ye (Q)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
ORCID: 0000-0002-3812-3001

Damian W Young (DW)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX 77030, USA.

Mingxing Teng (M)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX 77030, USA.
ORCID: 0000-0001-6574-1764

Choel Kim (C)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX 77030, USA.
ORCID: 0000-0002-3152-0020

Martin M Matzuk (MM)

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX 77030, USA.
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
ORCID: 0000-0002-1445-8632

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Reversible male contraception by targeted...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Reversible male contraception by targeted...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents régulateurs de la reproduction › Contraceptifs › Contraceptifs masculins › Reversible male contraception by targeted...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protein-Serine-Threonine Kinases › Reversible male contraception by targeted...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Reversible male contraception by targeted...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Antienzymes › Inhibiteurs de protéines kinases › Reversible male contraception by targeted...
questionsmedicales.fr › Système endocrine › Glandes endocrines › Gonades › Testicule › Reversible male contraception by targeted...
questionsmedicales.fr › Système cardiovasculaire › Barrière hématotesticulaire › Reversible male contraception by targeted...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Bibliothèques de petites molécules › Reversible male contraception by targeted...