Anomalous origin of the coronary artery: prevalence and coronary artery disease in adults undergoing coronary tomographic angiography.
Humans
Coronary Vessel Anomalies
/ diagnostic imaging
Prevalence
Male
Female
Middle Aged
Coronary Angiography
Computed Tomography Angiography
Coronary Artery Disease
/ diagnostic imaging
Aged
Retrospective Studies
Predictive Value of Tests
Adult
Risk Factors
Risk Assessment
Severity of Illness Index
Anomalous aortic origin of coronary artery
Coronary artery disease
Coronary computed tomographic angiography
Journal
BMC cardiovascular disorders
ISSN: 1471-2261
Titre abrégé: BMC Cardiovasc Disord
Pays: England
ID NLM: 100968539
Informations de publication
Date de publication:
23 May 2024
23 May 2024
Historique:
received:
15
05
2023
accepted:
15
05
2024
medline:
24
5
2024
pubmed:
24
5
2024
entrez:
23
5
2024
Statut:
epublish
Résumé
Anomalous aortic origin of a coronary artery (AAOCA) is a rare congenital coronary anomaly with the potential to cause adverse cardiac events. However, there is limited data on the association between AAOCA and coronary artery disease (CAD). Therefore, the aim of this study is to determine the prevalence and symptoms of patients with AAOCA, as well as investigate the correlation between AAOCA and CAD in a population referred for coronary computed tomographic angiography (CTA). All consecutive patients who underwent CTA from 2010 to 2021 were included. Characteristics, symptoms, coronary related adverse events and CTA information were reviewed by medical records. Separate multivariable cumulative logistic regressions were performed, using the stenosis severity in each of the four coronaries as individual responses and as a combined patient clustered response. Finally, we identified 207 adult patients with AAOCA, the prevalence of AAOCA is 0.23% (207/90,501). Moreover, this study found no significant association between AAOCA and CAD. AAOCA did not contribute to higher rates of hospitalization or adverse cardiac events, including calcification. AAOCA is a rare congenital disease that is not associated with increased presence of obstructive CAD in adults.
Sections du résumé
BACKGROUND
BACKGROUND
Anomalous aortic origin of a coronary artery (AAOCA) is a rare congenital coronary anomaly with the potential to cause adverse cardiac events. However, there is limited data on the association between AAOCA and coronary artery disease (CAD). Therefore, the aim of this study is to determine the prevalence and symptoms of patients with AAOCA, as well as investigate the correlation between AAOCA and CAD in a population referred for coronary computed tomographic angiography (CTA).
METHODS AND RESULTS
RESULTS
All consecutive patients who underwent CTA from 2010 to 2021 were included. Characteristics, symptoms, coronary related adverse events and CTA information were reviewed by medical records. Separate multivariable cumulative logistic regressions were performed, using the stenosis severity in each of the four coronaries as individual responses and as a combined patient clustered response. Finally, we identified 207 adult patients with AAOCA, the prevalence of AAOCA is 0.23% (207/90,501). Moreover, this study found no significant association between AAOCA and CAD. AAOCA did not contribute to higher rates of hospitalization or adverse cardiac events, including calcification.
CONCLUSION
CONCLUSIONS
AAOCA is a rare congenital disease that is not associated with increased presence of obstructive CAD in adults.
Identifiants
pubmed: 38783173
doi: 10.1186/s12872-024-03942-8
pii: 10.1186/s12872-024-03942-8
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
271Subventions
Organisme : Chongqing Key Laboratory of Cardiovascular Disease Research Project
ID : No. 2021YZZ07
Organisme : Chongqing Medical Scientific Research Project (Joint Project of Chongqing Health Commission and Science and Technology Bureau)
ID : No.2024ZDXM019
Informations de copyright
© 2024. The Author(s).
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