Clinicopathological and Molecular Analysis of Aqueous Humor for the Diagnosis of Feline Infectious Peritonitis.
FCoV PCR
FIP
cytology
diagnostic accuracy
feline coronavirus
ocular fluids
ocular proteins
Journal
Veterinary sciences
ISSN: 2306-7381
Titre abrégé: Vet Sci
Pays: Switzerland
ID NLM: 101680127
Informations de publication
Date de publication:
09 May 2024
09 May 2024
Historique:
received:
12
03
2024
revised:
05
05
2024
accepted:
07
05
2024
medline:
24
5
2024
pubmed:
24
5
2024
entrez:
24
5
2024
Statut:
epublish
Résumé
This study was designed to assess the diagnostic utility for FIP of cytology, protein measurement and RT-PCR for feline coronaviruses (FCoV) on aqueous humor (AH), since little information is currently available. AH samples ( The proportion of RT-PCR positive samples did not differ among groups, while positive cytology was more frequent in samples with FIP ( Based on the LR+, cytology and/or RT-PCR may support the diagnosis when the pre-test probability of FIP is high. The concentration of intraocular protein is a promising marker, especially in NE-FIP.
Sections du résumé
BACKGROUND
BACKGROUND
This study was designed to assess the diagnostic utility for FIP of cytology, protein measurement and RT-PCR for feline coronaviruses (FCoV) on aqueous humor (AH), since little information is currently available.
METHODS
METHODS
AH samples (
RESULTS
RESULTS
The proportion of RT-PCR positive samples did not differ among groups, while positive cytology was more frequent in samples with FIP (
CONCLUSIONS
CONCLUSIONS
Based on the LR+, cytology and/or RT-PCR may support the diagnosis when the pre-test probability of FIP is high. The concentration of intraocular protein is a promising marker, especially in NE-FIP.
Identifiants
pubmed: 38787179
pii: vetsci11050207
doi: 10.3390/vetsci11050207
pii:
doi:
Types de publication
Journal Article
Langues
eng