Near-Infrared Ratiometric Fluorescent Probe for Detecting Endogenous Cu

Arabidopsis Lewy body disease activity-based sensing copper cyanine fluorescent probe neuroblastoma photoacoustic imaging

Journal

ACS sensors
ISSN: 2379-3694
Titre abrégé: ACS Sens
Pays: United States
ID NLM: 101669031

Informations de publication

Date de publication:
24 May 2024
Historique:
medline: 24 5 2024
pubmed: 24 5 2024
entrez: 24 5 2024
Statut: aheadofprint

Résumé

Copper participates in a range of critical functions in the nervous system and human brain. Disturbances in brain copper content is strongly associated with neurological diseases. For example, changes in the level and distribution of copper are reported in neuroblastoma, Alzheimer's disease, and Lewy body disorders, such as Parkinson disease and dementia with Lewy bodies (DLB). There is a need for more sensitive techniques to measure intracellular copper levels to have a better understanding of the role of copper homeostasis in neuronal disorders. Here, we report a reaction-based near-infrared (NIR) ratiometric fluorescent probe

Identifiants

DOI: 10.1021/acssensors.3c02549 PMID: 38787339
pubmed: 38787339
doi: 10.1021/acssensors.3c02549
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Jianping Zhu (J)

School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.

Marcus E Graziotto (ME)

School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.

Veronica Cottam (V)

Brain and Mind Centre and School of Medical Sciences (Neuroscience), The University of Sydney, Sydney, NSW 2006, Australia.

Tom Hawtrey (T)

School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.
Sydney Nano Institute, The University of Sydney, Sydney, NSW 2006, Australia.
Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Sydney, Sydney, NSW 2006, Australia.

Liam D Adair (LD)

School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.
Sydney Nano Institute, The University of Sydney, Sydney, NSW 2006, Australia.
Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Sydney, Sydney, NSW 2006, Australia.
ORCID: 0000-0002-9527-4869

Benjamin G Trist (BG)

Brain and Mind Centre and School of Medical Sciences (Neuroscience), The University of Sydney, Sydney, NSW 2006, Australia.
ORCID: 0000-0002-0712-399X

Nguyen T H Pham (NTH)

Sydney Imaging, Core Research Facility, The University of Sydney, Sydney, NSW 2006, Australia.

Jourdin R C Rouaen (JRC)

Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, Randwick, NSW 2052, Australia.
ORCID: 0000-0002-6206-9463

Carolyn Ohno (C)

School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW 2006, Australia.

Marcus Heisler (M)

School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW 2006, Australia.

Orazio Vittorio (O)

Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, Randwick, NSW 2052, Australia.
School of Biomedical Sciences, University of New South Wales, Kensington, NSW 2031, Australia.

Kay L Double (KL)

Brain and Mind Centre and School of Medical Sciences (Neuroscience), The University of Sydney, Sydney, NSW 2006, Australia.

Elizabeth J New (EJ)

School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.
Sydney Nano Institute, The University of Sydney, Sydney, NSW 2006, Australia.
Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Sydney, Sydney, NSW 2006, Australia.
ORCID: 0000-0002-2310-254X

Classifications MeSH