Associations between fruit and vegetable intakes and incident depression in middle-aged and older adults from 10 diverse international longitudinal cohorts.

Depression Fruit Longitudinal study Older adults Vegetables

Journal

Journal of affective disorders
ISSN: 1573-2517
Titre abrégé: J Affect Disord
Pays: Netherlands
ID NLM: 7906073

Informations de publication

Date de publication:
22 May 2024
Historique:
received: 04 02 2024
revised: 26 04 2024
accepted: 18 05 2024
medline: 25 5 2024
pubmed: 25 5 2024
entrez: 24 5 2024
Statut: aheadofprint

Résumé

Emerging observational evidence supports a role for higher fruit and vegetable intake in protecting against the development of depression. However, there is a scarcity of research in older adults or in low- to middle-income countries (LMICs). Participants were 7801 community-based adults (mean age 68.6 ± 8.0 years, 55.8 % female) without depression, from 10 diverse cohorts, including four cohorts from LMICs. Fruit and vegetable intake was self-reported via comprehensive food frequency questionnaire, short food questionnaire or diet history. Depressive symptoms were assessed using validated measures, and depression defined applying validated cut-offs. The associations between baseline fruit and vegetable intakes and incident depression over a follow-up period of three to nine years were examined using Cox regression. Analyses were performed by cohort with results meta-analysed. There were 1630 cases of incident depression (21 % of participants) over 40,258 person-years of follow-up. Higher intake of fruit was associated with a lower risk of incident depression (HR 0.87, 95%CI [0.77, 0.99], I Diverse measures used across the different cohorts and the modest sample size of our study compared with prior studies may have prevented an association being detected for vegetable intake. Our study supports a role for fruit, but not vegetable intake in protecting against depression. Research investigating different types of fruits and vegetables using standardised measures in larger cohorts of older adults from low- and middle-income countries is warranted.

Sections du résumé

BACKGROUND BACKGROUND
Emerging observational evidence supports a role for higher fruit and vegetable intake in protecting against the development of depression. However, there is a scarcity of research in older adults or in low- to middle-income countries (LMICs).
METHODS METHODS
Participants were 7801 community-based adults (mean age 68.6 ± 8.0 years, 55.8 % female) without depression, from 10 diverse cohorts, including four cohorts from LMICs. Fruit and vegetable intake was self-reported via comprehensive food frequency questionnaire, short food questionnaire or diet history. Depressive symptoms were assessed using validated measures, and depression defined applying validated cut-offs. The associations between baseline fruit and vegetable intakes and incident depression over a follow-up period of three to nine years were examined using Cox regression. Analyses were performed by cohort with results meta-analysed.
RESULTS RESULTS
There were 1630 cases of incident depression (21 % of participants) over 40,258 person-years of follow-up. Higher intake of fruit was associated with a lower risk of incident depression (HR 0.87, 95%CI [0.77, 0.99], I
LIMITATIONS CONCLUSIONS
Diverse measures used across the different cohorts and the modest sample size of our study compared with prior studies may have prevented an association being detected for vegetable intake.
CONCLUSIONS CONCLUSIONS
Our study supports a role for fruit, but not vegetable intake in protecting against depression. Research investigating different types of fruits and vegetables using standardised measures in larger cohorts of older adults from low- and middle-income countries is warranted.

Identifiants

DOI: 10.1016/j.jad.2024.05.096 PMID: 38788860
pubmed: 38788860
pii: S0165-0327(24)00832-2
doi: 10.1016/j.jad.2024.05.096
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024. Published by Elsevier B.V.

Déclaration de conflit d'intérêts

Declaration of competing interest Henry Brodaty is or has been an advisory board member or consultant to Biogen, Eisai, Eli Lilly, Roche and Skin2Neuron. He is a Medical/Clinical Advisory Board member for Montefiore Homes and Cranbrook Care.

Auteurs

Annabel P Matison (AP)

Centre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, New South Wales, Australia. Electronic address: a.matison@unsw.edu.au.

Victoria M Flood (VM)

The University of Sydney, Faculty of Medicine and Health, New South Wales, Australia; University Centre for Rural Health, Northern Rivers, Lismore, University of Sydney, New South Wales, Australia.

Ben C P Lam (BCP)

School of Psychology and Public Health, La Trobe University, Victoria, Australia.

Darren M Lipnicki (DM)

Centre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, New South Wales, Australia.

Katherine L Tucker (KL)

Department of Biomedical & Nutritional Sciences, Center for Population Health, University of Massachusetts Lowell, Lowell, USA.

Pierre-Marie Preux (PM)

Inserm U1094, IRD UMR270, Univ. Limoges, CHU Limoges, EpiMaCT - Epidemiology of Chronic Diseases in Tropical Zone, Institute of Epidemiology and Tropical Neurology, OmegaHealth, Limoges, France.

Maëlenn Guerchet (M)

Inserm U1094, IRD UMR270, Univ. Limoges, CHU Limoges, EpiMaCT - Epidemiology of Chronic Diseases in Tropical Zone, Institute of Epidemiology and Tropical Neurology, OmegaHealth, Limoges, France.

Eleonora d'Orsi (E)

Federal University of Santa Catarina, Trindade University Campus, Florianópolis, Santa Catarina, Brazil.

Anna Quialheiro (A)

Federal University of Santa Catarina, Trindade University Campus, Florianópolis, Santa Catarina, Brazil; IA&Saúde - The Artificial Intelligence and Health Research Unit, Instituto Politécnico de Saúde do Norte, CESPU, Vila Nova de Famalicão, Portugal.

Cassiano R Rech (CR)

Federal University of Santa Catarina, Program in Postgraduate Physical Education, Santa Catarina, Brazil.

Ingmar Skoog (I)

Section of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden.

Jenna Najar (J)

Section of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden; Department of Human Genetics, Genomics of Neurodegenerative Diseases and Aging at the Amsterdam University Medical Center, Amsterdam, Netherlands.

Therese Rydberg Sterner (TR)

Section of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden; Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

Nikolaos Scarmeas (N)

Department of Neurology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece; Department of Neurology, Columbia University, New York, NY, USA.

Mary H Kosmidis (MH)

Lab of Neuropsychology & Behavioral Neuroscience, School of Psychology, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Mary Yannakoulia (M)

Department of Nutrition and Dietetics, School of Health Sciences and Education, Harokopio University, Athens, Greece.

Oye Gureje (O)

University of Ibadan, World Health Organization Collaborating Centre for Research and Training in Mental Health, Neurosciences and Substance Abuse, Department of Psychiatry, Ibadan, Nigeria.

Akin Ojagbemi (A)

University of Ibadan, World Health Organization Collaborating Centre for Research and Training in Mental Health, Neurosciences and Substance Abuse, Department of Psychiatry, Ibadan, Nigeria.

Toyin Bello (T)

University of Ibadan, World Health Organization Collaborating Centre for Research and Training in Mental Health, Neurosciences and Substance Abuse, Department of Psychiatry, Ibadan, Nigeria.

Suzana Shahar (S)

Center for Healthy Ageing & Wellness (H-CARE), Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur, Malaysia.

Nik N N Fakhruddin (NNN)

Jeffrey Cheah School of Medicine & Health Sciences, Monash University Malaysia, Jalan Lagoon Selatan, 47500 Bandar Sunway, Selangor, Malaysia.

Nurul F M Rivan (NFM)

Center for Healthy Ageing & Wellness (H-CARE), Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur, Malaysia.

Kaarin J Anstey (KJ)

UNSW Ageing Futures Institute, University of New South Wales, Sydney, Australia; Neuroscience Research Australia, Sydney, Australia.

Nicolas Cherbuin (N)

National Centre for Epidemiology and Population Health, Australian National University, Canberra, Australia.

Moyra Mortby (M)

UNSW Ageing Futures Institute, University of New South Wales, Sydney, Australia.

Roger Ho (R)

Department of Psychological Medicine, National University of Singapore, Singapore.

Henry Brodaty (H)

Centre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, New South Wales, Australia.

Perminder S Sachdev (PS)

Centre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, New South Wales, Australia; Neuropsychiatric Institute, Prince of Wales Hospital, New South Wales, Australia.

Simone Reppermund (S)

Centre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, New South Wales, Australia; Department of Developmental Disability Neuropsychiatry (3DN), Discipline of Psychiatry and Mental Health, Faculty of Medicine and Health, UNSW Sydney, New South Wales, Australia.

Karen A Mather (KA)

Centre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, New South Wales, Australia.

Classifications MeSH