Challenges of Robust RNAi-Mediated Gene Silencing in

Animals Aedes / genetics RNA Interference RNA, Small Interfering / genetics Mosquito Vectors / genetics Larva / genetics RNA, Double-Stranded / genetics Gene Silencing Gene Knockdown Techniques / methods
Aedes aegypti Aedes albopictus RNA interference RNAi delivery methods RNAi-based pest control reproducibility of RNAi protocols

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
10 May 2024
Historique:
received: 20 03 2024
revised: 03 05 2024
accepted: 05 05 2024
medline: 25 5 2024
pubmed: 25 5 2024
entrez: 25 5 2024
Statut: epublish

Résumé

In this study, we report the complexities and challenges associated with achieving robust RNA interference (RNAi)-mediated gene knockdown in the mosquitoes

Identifiants

DOI: 10.3390/ijms25105218 PMID: 38791257
pubmed: 38791257
pii: ijms25105218
doi: 10.3390/ijms25105218
pii:
doi:

Substances chimiques

RNA, Small Interfering 0
RNA, Double-Stranded 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : German Academic Exchange Service
ID : 57507871

Auteurs

Lucas Henrique Figueiredo Prates (LH)

Department of Insect Biotechnology in Plant Protection, Justus Liebig University Giessen, 35394 Giessen, Germany.
ORCID: 0000-0003-0739-5597

Jakob Fiebig (J)

Department of Insect Biotechnology in Plant Protection, Justus Liebig University Giessen, 35394 Giessen, Germany.

Henrik Schlosser (H)

Department of Insect Biotechnology in Plant Protection, Justus Liebig University Giessen, 35394 Giessen, Germany.
ORCID: 0009-0009-1217-0692

Eleni Liapi (E)

Department of Biochemistry and Biotechnology, University of Thessaly, 41500 Larissa, Greece.
ORCID: 0009-0000-7175-8618

Tanja Rehling (T)

Department of Insect Biotechnology in Plant Protection, Justus Liebig University Giessen, 35394 Giessen, Germany.
ORCID: 0000-0003-4173-9816

Célia Lutrat (C)

ASTRE, CIRAD, 34398 Montpellier, France.
ORCID: 0000-0003-3440-8939

Jeremy Bouyer (J)

ASTRE, CIRAD, 34398 Montpellier, France.
ASTRE, CIRAD, INRAE, Univ. Montpellier, Plateforme Technologique CYROI, 97491 Sainte-Clotilde, La Réunion, France.
ORCID: 0000-0002-1913-416X

Qiang Sun (Q)

Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 48824, USA.

Han Wen (H)

Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 48824, USA.
ORCID: 0000-0003-1820-3220

Zhiyong Xi (Z)

Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 48824, USA.
ORCID: 0000-0001-7786-012X

Marc F Schetelig (MF)

Department of Insect Biotechnology in Plant Protection, Justus Liebig University Giessen, 35394 Giessen, Germany.
ORCID: 0000-0002-9217-394X

Irina Häcker (I)

Department of Insect Biotechnology in Plant Protection, Justus Liebig University Giessen, 35394 Giessen, Germany.
ORCID: 0000-0003-4022-4853

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Challenges of Robust RNAi-Mediated Gene Silencing in
questionsmedicales.fr › Eucaryotes › Animaux › Invertébrés › Arthropodes › Insectes › Pterygota › Neoptera › Holometabola › Diptera › Nematocera › Culicomorpha › Culicidae › Aedes › Challenges of Robust RNAi-Mediated Gene Silencing in
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Épigenèse génétique › Extinction de l'expression des gènes › Interférence par ARN › Challenges of Robust RNAi-Mediated Gene Silencing in
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN non traduit › Petit ARN non traduit › Petit ARN interférent › Challenges of Robust RNAi-Mediated Gene Silencing in
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Chaîne d'infection › Vecteurs de maladies › Vecteurs arthropodes › Vecteurs insectes › Vecteurs moustiques › Challenges of Robust RNAi-Mediated Gene Silencing in
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Morphogenèse › Métamorphose biologique › Étapes du cycle de vie › Larve › Challenges of Robust RNAi-Mediated Gene Silencing in
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Conformation d'acide nucléique › ARN double brin › Challenges of Robust RNAi-Mediated Gene Silencing in
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Épigenèse génétique › Extinction de l'expression des gènes › Challenges of Robust RNAi-Mediated Gene Silencing in
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Ciblage de gène › Techniques de knock-down de gènes › Challenges of Robust RNAi-Mediated Gene Silencing in