Antimalarial Activity of Aqueous Extracts of Nasturtium (

Antimalarials / pharmacology Plant Extracts / pharmacology Isothiocyanates / pharmacology Plasmodium falciparum / drug effects Nasturtium / chemistry Humans Plant Leaves / chemistry Seeds / chemistry Chloroquine / pharmacology
Plasmodium falciparum Tropaeolum majus L. antimalarials benzyl isothiocyanate

Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
15 May 2024
Historique:
received: 08 03 2024
revised: 04 05 2024
accepted: 10 05 2024
medline: 25 5 2024
pubmed: 25 5 2024
entrez: 25 5 2024
Statut: epublish

Résumé

Malaria remains an important and challenging infectious disease, and novel antimalarials are required. Benzyl isothiocyanate (BITC), the main breakdown product of benzyl glucosinolate, is present in all parts of

Identifiants

DOI: 10.3390/molecules29102316 PMID: 38792178
pubmed: 38792178
pii: molecules29102316
doi: 10.3390/molecules29102316
pii:
doi:

Substances chimiques

Antimalarials 0
Plant Extracts 0
Isothiocyanates 0
benzyl isothiocyanate 871J6YOR8Q
Chloroquine 886U3H6UFF

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Fundação para a Ciência e Tecnologia
ID : GHTMUID/04413/2020
Organisme : Fundação para a Ciência e Tecnologia
ID : LA-REAL - LA/P/0117/2020

Auteurs

Ana Maria Pintão (AM)

Egas Moniz School of Health & Science, University Campus, Quinta da Granja Monte da Caparica, 2829-511 Caparica, Portugal.
Egas Moniz Center for Interdisciplinary Research (CiiEM), Egas Moniz School of Health & Science, University Campus, Quinta da Granja Monte da Caparica, 2829-511 Caparica, Portugal.
ORCID: 0000-0002-2301-5358

Tiago Santos (T)

Instituto de Higiene e Medicina Tropical (IHMT), Universidade NOVA de Lisboa, Rua da Junqueira 100, 1349-008 Lisboa, Portugal.
Global Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade NOVA de Lisboa, UNL, Rua da Junqueira 100, 1349-008 Lisboa, Portugal.
ORCID: 0000-0003-3945-1880

Fátima Nogueira (F)

Instituto de Higiene e Medicina Tropical (IHMT), Universidade NOVA de Lisboa, Rua da Junqueira 100, 1349-008 Lisboa, Portugal.
Global Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade NOVA de Lisboa, UNL, Rua da Junqueira 100, 1349-008 Lisboa, Portugal.
LAQV-REQUIMTE, MolSyn, IHMT, Universidade NOVA de Lisboa, UNL, Rua da Junqueira 100, 1349-008 Lisboa, Portugal.
ORCID: 0000-0003-0313-0778

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiparasitaires › Antiprotozoaires › Antipaludiques › Antimalarial Activity of Aqueous Extracts of...
questionsmedicales.fr › Préparations pharmaceutiques › Extraits de plantes › Antimalarial Activity of Aqueous Extracts of...
questionsmedicales.fr › Composés chimiques organiques › Composés du soufre › Isothiocyanates › Antimalarial Activity of Aqueous Extracts of...
questionsmedicales.fr › Eucaryotes › Alveolata › Apicomplexa › Haemosporida › Plasmodium › Plasmodium falciparum › Antimalarial Activity of Aqueous Extracts of...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Brassicaceae › Nasturtium › Antimalarial Activity of Aqueous Extracts of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Antimalarial Activity of Aqueous Extracts of...
questionsmedicales.fr › Structures de plante › Parties aériennes de plante › Feuilles de plante › Antimalarial Activity of Aqueous Extracts of...
questionsmedicales.fr › Aliments et boissons › Aliments › Graines › Antimalarial Activity of Aqueous Extracts of...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Quinoléines › Aminoquinoléines › Chloroquine › Antimalarial Activity of Aqueous Extracts of...