New Thiazolidine-4-One Derivatives as SARS-CoV-2 Main Protease Inhibitors.

COVID-19 SARS-CoV-2 docking studies main protease small molecules thiazolidinone derivatives

Journal

Pharmaceuticals (Basel, Switzerland)
ISSN: 1424-8247
Titre abrégé: Pharmaceuticals (Basel)
Pays: Switzerland
ID NLM: 101238453

Informations de publication

Date de publication:
17 May 2024
Historique:
received: 15 04 2024
revised: 10 05 2024
accepted: 15 05 2024
medline: 25 5 2024
pubmed: 25 5 2024
entrez: 25 5 2024
Statut: epublish

Résumé

It has been more than four years since the first report of SARS-CoV-2, and humankind has experienced a pandemic with an unprecedented impact. Moreover, the new variants have made the situation even worse. Among viral enzymes, the SARS-CoV-2 main protease (M

Identifiants

DOI: 10.3390/ph17050650 PMID: 38794220
pubmed: 38794220
pii: ph17050650
doi: 10.3390/ph17050650
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : MUR PNRR Extended Partnership initiative on Emerging Infectious Diseases
ID : Project no. PE00000007, INF-ACT, Spoke 5

Auteurs

Antonella Messore (A)

Istituto Pasteur-Fondazione Cenci Bolognetti, Dipartimento di Chimica e Tecnologie del Farmaco, "Sapienza" Università di Roma, p.le Aldo Moro 5, 00185 Rome, Italy.

Paolo Malune (P)

Department of Life and Environmental Sciences, Faculty of Biology and Pharmacy, University of Cagliari, Cittadella Universitaria di Monserrato, ss554 Km 4500, 09045 Monserrato, Cagliari, Italy.
ORCID: 0000-0003-2946-2412

Elisa Patacchini (E)

Istituto Pasteur-Fondazione Cenci Bolognetti, Dipartimento di Chimica e Tecnologie del Farmaco, "Sapienza" Università di Roma, p.le Aldo Moro 5, 00185 Rome, Italy.
ORCID: 0000-0002-4531-3612

Valentina Noemi Madia (VN)

Istituto Pasteur-Fondazione Cenci Bolognetti, Dipartimento di Chimica e Tecnologie del Farmaco, "Sapienza" Università di Roma, p.le Aldo Moro 5, 00185 Rome, Italy.
ORCID: 0000-0002-5724-612X

Davide Ialongo (D)

Istituto Pasteur-Fondazione Cenci Bolognetti, Dipartimento di Chimica e Tecnologie del Farmaco, "Sapienza" Università di Roma, p.le Aldo Moro 5, 00185 Rome, Italy.
ORCID: 0000-0002-4672-2936

Merve Arpacioglu (M)

Istituto Pasteur-Fondazione Cenci Bolognetti, Dipartimento di Chimica e Tecnologie del Farmaco, "Sapienza" Università di Roma, p.le Aldo Moro 5, 00185 Rome, Italy.

Aurora Albano (A)

Istituto Pasteur-Fondazione Cenci Bolognetti, Dipartimento di Chimica e Tecnologie del Farmaco, "Sapienza" Università di Roma, p.le Aldo Moro 5, 00185 Rome, Italy.

Giuseppe Ruggieri (G)

Istituto Pasteur-Fondazione Cenci Bolognetti, Dipartimento di Chimica e Tecnologie del Farmaco, "Sapienza" Università di Roma, p.le Aldo Moro 5, 00185 Rome, Italy.

Francesco Saccoliti (F)

Istituto Pasteur-Fondazione Cenci Bolognetti, Dipartimento di Chimica e Tecnologie del Farmaco, "Sapienza" Università di Roma, p.le Aldo Moro 5, 00185 Rome, Italy.
ORCID: 0000-0002-2907-5503

Luigi Scipione (L)

Istituto Pasteur-Fondazione Cenci Bolognetti, Dipartimento di Chimica e Tecnologie del Farmaco, "Sapienza" Università di Roma, p.le Aldo Moro 5, 00185 Rome, Italy.
ORCID: 0000-0002-2006-7005

Enzo Tramontano (E)

Department of Life and Environmental Sciences, Faculty of Biology and Pharmacy, University of Cagliari, Cittadella Universitaria di Monserrato, ss554 Km 4500, 09045 Monserrato, Cagliari, Italy.
ORCID: 0000-0002-4849-0980

Serena Canton (S)

Department of Life and Environmental Sciences, Faculty of Biology and Pharmacy, University of Cagliari, Cittadella Universitaria di Monserrato, ss554 Km 4500, 09045 Monserrato, Cagliari, Italy.

Angela Corona (A)

Department of Life and Environmental Sciences, Faculty of Biology and Pharmacy, University of Cagliari, Cittadella Universitaria di Monserrato, ss554 Km 4500, 09045 Monserrato, Cagliari, Italy.
ORCID: 0000-0002-6630-8636

Sante Scognamiglio (S)

Department of Life and Environmental Sciences, Faculty of Biology and Pharmacy, University of Cagliari, Cittadella Universitaria di Monserrato, ss554 Km 4500, 09045 Monserrato, Cagliari, Italy.
ORCID: 0000-0003-3076-1823

Annalaura Paulis (A)

Department of Life and Environmental Sciences, Faculty of Biology and Pharmacy, University of Cagliari, Cittadella Universitaria di Monserrato, ss554 Km 4500, 09045 Monserrato, Cagliari, Italy.
ORCID: 0000-0001-6403-8639

Mustapha Suleiman (M)

Department of Chemistry, Sokoto State University, Sokoto 852101, Nigeria.

Helmi Mohammed Al-Maqtari (HM)

Department of Chemistry, College of Education, Hodeidah University, Hodeidah 207416, Yemen.

Fatma Mohamed A Abid (FMA)

Department of Chemistry, Faculty of Science, Al-Azzaytuna University, Tarhuna 537622224, Libya.

Sarkar M A Kawsar (SMA)

Laboratory of Carbohydrate and Nucleoside Chemistry, Department of Chemistry, University of Chittagong, Chittagong 4331, Bangladesh.
ORCID: 0000-0001-7964-9117

Murugesan Sankaranarayanan (M)

Medicinal Chemistry Research Laboratory, Birla Institute of Technology and Science Pilani, Pilani Campus, Pilani 333031, Rajasthan, India.
ORCID: 0000-0002-3680-1577

Roberto Di Santo (R)

Istituto Pasteur-Fondazione Cenci Bolognetti, Dipartimento di Chimica e Tecnologie del Farmaco, "Sapienza" Università di Roma, p.le Aldo Moro 5, 00185 Rome, Italy.
ORCID: 0000-0002-4279-7666

Francesca Esposito (F)

Department of Life and Environmental Sciences, Faculty of Biology and Pharmacy, University of Cagliari, Cittadella Universitaria di Monserrato, ss554 Km 4500, 09045 Monserrato, Cagliari, Italy.
ORCID: 0000-0001-9725-7977

Roberta Costi (R)

Istituto Pasteur-Fondazione Cenci Bolognetti, Dipartimento di Chimica e Tecnologie del Farmaco, "Sapienza" Università di Roma, p.le Aldo Moro 5, 00185 Rome, Italy.

Classifications MeSH